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7MXP
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BU of 7mxp by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Reddem, E.R, Casner, R.G, Shapiro, L.
Deposit date:2021-05-19
Release date:2022-05-25
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2.
Aiche J, 67, 2021
5K6Z
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BU of 5k6z by Molmil
Sidekick chimera containing sidekick-2 immunoglobulin domains 1-2 and sidekick-1 immunoglobulin domains 3-4
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
Deposit date:2016-05-25
Release date:2016-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of sidekick-mediated cell-cell adhesion and specificity.
Elife, 5, 2016
5K6W
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BU of 5k6w by Molmil
Sidekick-1 immunoglobulin domains 1-5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
Deposit date:2016-05-25
Release date:2016-09-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular basis of sidekick-mediated cell-cell adhesion and specificity.
Elife, 5, 2016
1L3W
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BU of 1l3w by Molmil
C-cadherin Ectodomain
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L.
Deposit date:2002-03-01
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:C-cadherin ectodomain structure and implications for cell adhesion mechanisms
Science, 296, 2002
1XXL
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BU of 1xxl by Molmil
The crystal structure of YcgJ protein from Bacillus subitilis at 2.1 A resolution
Descriptor: SULFATE ION, YcgJ protein
Authors:Burke, T.A, Gorman, J, Shaprio, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-11-05
Release date:2004-11-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of YcgJ protein from Bacillus subitilis at 2.1 A resolution
To be Published
1JVK
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BU of 1jvk by Molmil
THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR
Descriptor: IMMUNOGLOBULIN LAMBDA LIGHT CHAIN
Authors:Bourne, P.C, Ramsland, P.A, Shan, L, Fan, Z.-C, DeWitt, C.R, Shultz, B.B, Terzyan, S.S, Edmundson, A.B.
Deposit date:2001-08-30
Release date:2002-05-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties.
Acta Crystallogr.,Sect.D, 58, 2002
2AWD
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BU of 2awd by Molmil
Crystal structure of LacC from Enterococcus faecalis
Descriptor: BROMIDE ION, tagatose-6-phosphate kinase
Authors:Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-08-31
Release date:2005-09-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of LacC from Enterococcus faecalis
To be Published
1M0T
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BU of 1m0t by Molmil
Yeast Glutathione Synthase
Descriptor: SULFATE ION, glutathione synthetase
Authors:Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-06-14
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase
Structure, 10, 2002
2F3W
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BU of 2f3w by Molmil
solution structure of 1-110 fragment of staphylococcal nuclease in 2M TMAO
Descriptor: Thermonuclease
Authors:Liu, D, Xie, T, Feng, Y, Shan, L, Ye, K, Wang, J.
Deposit date:2005-11-22
Release date:2006-12-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2ESR
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BU of 2esr by Molmil
conserved hypothetical protein- streptococcus pyogenes
Descriptor: Methyltransferase, alpha-D-glucopyranose
Authors:Jiang, J, Min, T, Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-10-26
Release date:2006-02-07
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of hypothetical protein of Streptococcus Pygenes
To be Published
1DQL
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BU of 1dql by Molmil
CRYSTAL STRUCTURE OF AN UNLIGANDED (NATIVE) FV FROM A HUMAN IGM ANTI-PEPTIDE ANTIBODY
Descriptor: IGM MEZ IMMUNOGLOBULIN
Authors:Ramsland, P.A, Shan, L, Moomaw, C.R, Slaughter, C.A, Guddat, L.W, Edmundson, A.B.
Deposit date:2000-01-04
Release date:2000-10-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An unusual human IgM antibody with a protruding HCDR3 and high avidity for its peptide ligands.
Mol.Immunol., 37, 2000
9IY0
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BU of 9iy0 by Molmil
anti-HEV mAb 8H3
Descriptor: Heavy chain of 8H3 Fab, Light chain of 8H3 Fab, MAGNESIUM ION
Authors:Minghua, Z, Lizhi, Z, Yang, H, Ying, G, Shaowei, L.
Deposit date:2024-07-29
Release date:2024-09-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis for the synergetic neutralization of hepatitis E virus by antibody-antibody interaction
To Be Published
8TNL
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BU of 8tnl by Molmil
CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.HK1 Neutralizing Antibody Heavy Chain, Hemagglutinin
Authors:Morano, N.C, Wu, X, Shapiro, L.
Deposit date:2023-08-02
Release date:2024-05-15
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head.
Nat Commun, 15, 2024
8TOA
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BU of 8toa by Molmil
CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.HK2 Neutralizing Antibody Heavy Chain, H7.HK2 Neutralizing Antibody Light Chain, ...
Authors:Morano, N.C, Becker, J.E, Wu, X, Shapiro, L.
Deposit date:2023-08-03
Release date:2024-05-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1
To Be Published
8TJR
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BU of 8tjr by Molmil
CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody HERH-a.01 Heavy Chain, ...
Authors:Morano, N.C, Hoyt, F, Hansen, B, Fischer, E, Shapiro, L.
Deposit date:2023-07-24
Release date:2024-07-31
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB
To Be Published
8TJS
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BU of 8tjs by Molmil
CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO GPZ6-a.01 FAB
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody GPZ6-a.01 Heavy Chain, ...
Authors:Morano, N.C, Becker, J.E, Shapiro, L.
Deposit date:2023-07-24
Release date:2024-07-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO GPZ6-a.01 FAB
To Be Published
8DUL
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BU of 8dul by Molmil
Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ...
Authors:Cerutti, G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-07-27
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DUN
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BU of 8dun by Molmil
Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ...
Authors:Cerutti, G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-07-27
Release date:2023-07-05
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (5.84 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8TXU
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BU of 8txu by Molmil
Fab 3864-10 in complex with influenza HA H3-SING16
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 3864-10 Heavy Chain, Fab 3864-10 Light Chain, ...
Authors:Morano, N.C, Shapiro, L.
Deposit date:2023-08-24
Release date:2024-09-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Fab 3864-6 in complex with influenza HA H3-VIC11
To Be Published
8TX3
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BU of 8tx3 by Molmil
Fab 3864-6 in complex with influenza HA H3-VIC11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 3864-6 Heavy Chain, Fab 3864-6 Light Chain, ...
Authors:Morano, N.C, Shapiro, L.
Deposit date:2023-08-22
Release date:2024-09-11
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Fab 3864-6 in complex with influenza HA H3-VIC11
To Be Published
6WU5
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BU of 6wu5 by Molmil
Human Calcium and Integrin Binding Protein 3
Descriptor: CALCIUM ION, CHLORIDE ION, Calcium and integrin-binding family member 3, ...
Authors:Dionne, G, Shapiro, L.
Deposit date:2020-05-04
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Neuron, 109, 2021
8EYZ
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BU of 8eyz by Molmil
Engineered glutamine binding protein bound to GLN and a cobaloxime ligand
Descriptor: AZIDOBIS (DIMETHYLGLYOXIMATO) PYRIDINECOBALT, Amino acid ABC transporter substrate-binding protein, GLUTAMINE, ...
Authors:Bridwell-Rabb, J, Boggs, D.G, Olshansky, L, Fatima, S, Thompson, P.
Deposit date:2022-10-29
Release date:2022-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Engineering a Conformationally Switchable Artificial Metalloprotein.
J.Am.Chem.Soc., 144, 2022
8EM4
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BU of 8em4 by Molmil
Cryo-EM structure of LRP2 at pH 7.5
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-26
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
8EM7
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BU of 8em7 by Molmil
Cryo-EM structure of LRP2 at pH 5.2
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-27
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
6XSK
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BU of 6xsk by Molmil
Cryo-EM Structure of Vaccine-Elicited Rhesus Antibody 789-203-3C12 in Complex with Stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 789-203-3C12 Fab Heavy Chain, ...
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-07-15
Release date:2021-07-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Immunity, 55, 2022

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數據於2024-10-30公開中

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