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1KPL
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BU of 1kpl by Molmil
Crystal Structure of the ClC Chloride Channel from S. typhimurium
Descriptor: CHLORIDE ION, N-OCTANE, PENTADECANE, ...
Authors:Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R.
Deposit date:2001-12-31
Release date:2002-01-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
6XIS
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BU of 6xis by Molmil
Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in apo form
Descriptor: G protein-activated inward rectifier potassium channel 2
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2020-06-21
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.
Elife, 9, 2020
6PBY
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BU of 6pby by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 1)
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2019-06-14
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Regulation of Eag1 gating by its intracellular domains.
Elife, 8, 2019
6PBX
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BU of 6pbx by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2)
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2019-06-14
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Regulation of Eag1 gating by its intracellular domains.
Elife, 8, 2019
6XIT
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BU of 6xit by Molmil
Cryo-EM structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with PIP2
Descriptor: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2020-06-21
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of PIP 2 regulation in mammalian GIRK channels.
Elife, 9, 2020
1N9P
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BU of 1n9p by Molmil
Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier Potassium Channel 1
Descriptor: G protein-activated inward rectifier potassium channel 1
Authors:Nishida, M, MacKinnon, R.
Deposit date:2002-11-26
Release date:2003-01-07
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Inward Rectification: Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 A Resolution
Cell(Cambridge,Mass.), 111, 2002
1ORS
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BU of 1ors by Molmil
X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab
Descriptor: 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel
Authors:Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
Deposit date:2003-03-14
Release date:2003-05-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
1ORQ
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BU of 1orq by Molmil
X-ray structure of a voltage-dependent potassium channel in complex with an Fab
Descriptor: 6E1 Fab heavy chain, 6E1 Fab light chain, CADMIUM ION, ...
Authors:Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
Deposit date:2003-03-14
Release date:2003-05-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
7S5Y
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BU of 7s5y by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S5Z
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BU of 7s5z by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
1QRQ
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BU of 1qrq by Molmil
STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (KV BETA2 PROTEIN)
Authors:Gulbis, J.M, Mann, S, MacKinnon, R.
Deposit date:1999-06-15
Release date:1999-10-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a voltage-dependent K+ channel beta subunit.
Cell(Cambridge,Mass.), 97, 1999
5VA2
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BU of 5va2 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
5U6O
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BU of 5u6o by Molmil
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel
Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Authors:Lee, C.-H, MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5U6P
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BU of 5u6p by Molmil
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11
Authors:Lee, C.-H, MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5U70
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BU of 5u70 by Molmil
Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl
Descriptor: Potassium channel subfamily T member 1
Authors:Hite, R.K, MacKinnon, R.
Deposit date:2016-12-09
Release date:2017-02-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel.
Cell, 168, 2017
5TR1
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BU of 5tr1 by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
Descriptor: CHOLESTEROL HEMISUCCINATE, Chloride channel protein, Monoclonal antibody, ...
Authors:Park, E, MacKinnon, R.
Deposit date:2016-10-25
Release date:2017-01-11
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
5VA3
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BU of 5va3 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
5U76
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BU of 5u76 by Molmil
Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl
Descriptor: Potassium channel subfamily T member 1
Authors:Hite, R.K, MacKinnon, R.
Deposit date:2016-12-11
Release date:2017-02-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel.
Cell, 168, 2017
5TQQ
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BU of 5tqq by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation
Descriptor: Chloride channel protein, Monoclonal antibody, Fab fragment, ...
Authors:Park, E, MacKinnon, R.
Deposit date:2016-10-24
Release date:2017-01-04
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
5VA1
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BU of 5va1 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
7S5X
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BU of 7s5x by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S5V
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BU of 7s5v by Molmil
Human KATP channel in open conformation, focused on SUR
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S5T
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BU of 7s5t by Molmil
Human KATP channel in open conformation, focused on Kir (C166S G334D double mutant) and SUR TMD0
Descriptor: ATP-sensitive inward rectifier potassium channel 11, POTASSIUM ION
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S61
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BU of 7s61 by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 5
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7S60
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BU of 7s60 by Molmil
Human KATP channel in open conformation, focused on Kir and one SUR, position 4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Zhao, C, MacKinnon, R.
Deposit date:2021-09-12
Release date:2021-12-01
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021

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數據於2024-10-09公開中

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