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6U2K
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BU of 6u2k by Molmil
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
5CDZ
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BU of 5cdz by Molmil
Crystal structure of conserpin in the latent state
Descriptor: Conserpin in the latent state, GLYCEROL
Authors:Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CE0
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BU of 5ce0 by Molmil
Crystal structure of conserpin with Z-mutation
Descriptor: Native conserpin with Z-variant (E342K)
Authors:Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CDX
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BU of 5cdx by Molmil
Crystal structure of conserpin
Descriptor: Conserpin
Authors:Porebski, B.T, Borg, N.A, McGowan, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
6OKW
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BU of 6okw by Molmil
Solution structure of VEK50
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-15
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OKY
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BU of 6oky by Molmil
Solution structure of truncated peptide from PAMap53
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-15
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OKX
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BU of 6okx by Molmil
Solution structure of VEK50RH1/AA
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-15
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OQ9
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BU of 6oq9 by Molmil
Solution structure of VEK50 in the bound form with plasminogen kringle 2
Descriptor: Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-25
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OQK
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BU of 6oqk by Molmil
SOLUTION STRUCTURE OF THE COMPLEX OF MUTANT VEK50[RH2/AA] AND PLASMINOGEN KRINGLE 2
Descriptor: Plasminogen Kringle 2, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-26
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
6OQJ
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BU of 6oqj by Molmil
SOLUTION STRUCTURE OF THE COMPLEX OF MUTANT VEK50[RH1/AA] AND PLASMINOGEN KRINGLE 2
Descriptor: Plasminogen kringle 2, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Yuan, Y, Castellino, F.J.
Deposit date:2019-04-26
Release date:2019-07-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
2GRV
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BU of 2grv by Molmil
Crystal Structure of LpqW
Descriptor: LpqW
Authors:Marland, Z, Rossjohn, J.
Deposit date:2006-04-25
Release date:2006-07-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis
J.Mol.Biol., 359, 2006
6CXO
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BU of 6cxo by Molmil
Complement component-9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ...
Authors:Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T.
Deposit date:2018-04-03
Release date:2018-09-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6D3Z
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BU of 6d3z by Molmil
Protease SFTI complex
Descriptor: Plasminogen, Trypsin inhibitor 1
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
7MP6
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BU of 7mp6 by Molmil
Neurofibromin homodimer
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-04
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (6.25 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MP5
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BU of 7mp5 by Molmil
Autoinhibited neurofibrobmin
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-04
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MOC
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BU of 7moc by Molmil
Neurofibromin core
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-01
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.56 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
6DLW
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BU of 6dlw by Molmil
Complement component polyC9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose
Authors:Dunstone, M.A, Spicer, B.A, Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6D40
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BU of 6d40 by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: Plasminogen, SULFATE ION, Trypsin inhibitor 1
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
6D3Y
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BU of 6d3y by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: GLYCEROL, Plasminogen, SULFATE ION, ...
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
6D3X
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BU of 6d3x by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: Plasminogen, Trypsin inhibitor 1
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
3BJX
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BU of 3bjx by Molmil
Structure of a Group I haloacid dehalogenase from Pseudomonas putida strain PP3
Descriptor: Halocarboxylic acid dehalogenase DehI, SULFATE ION
Authors:Schmidberger, J.W, Wilce, M.C.J.
Deposit date:2007-12-05
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of DehI reveals a new alpha-haloacid dehalogenase fold and active-site mechanism
J.Mol.Biol., 378, 2008
4ES8
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BU of 4es8 by Molmil
Crystal Structure of the adhesin domain of Epf from Streptococcus pyogenes in P212121
Descriptor: ACETATE ION, Epf, GLYCEROL, ...
Authors:Linke, C, Siemens, N, Kreikemeyer, B, Baker, E.N.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module.
J.Biol.Chem., 287, 2012
4EME
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BU of 4eme by Molmil
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase
Descriptor: M18 aspartyl aminopeptidase, ZINC ION
Authors:McGowan, S.
Deposit date:2012-04-11
Release date:2012-06-27
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.
J.Mol.Biol., 422, 2012
4ES9
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BU of 4es9 by Molmil
Crystal Structure of the adhesin domain of Epf from Streptococcus pyogenes in P21
Descriptor: Epf
Authors:Linke, C, Siemens, N, Kreikemeyer, B, Baker, E.N.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module.
J.Biol.Chem., 287, 2012
4G8R
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BU of 4g8r by Molmil
Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1
Descriptor: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION
Authors:Stuckey, J.A, Lawrence, D.A, Li, S.-H.
Deposit date:2012-07-23
Release date:2013-12-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013

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數據於2024-05-29公開中

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