1OL5
 
 | | Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ... | | Authors: | Bayliss, R, Conti, E. | | Deposit date: | 2003-08-06 | | Release date: | 2003-10-30 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
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1A0E
 | | XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA | | Descriptor: | COBALT (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1HL6
 | | A novel mode of RBD-protein recognition in the Y14-mago complex | | Descriptor: | CG8781 PROTEIN, MAGO NASHI PROTEIN | | Authors: | Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E. | | Deposit date: | 2003-03-13 | | Release date: | 2003-05-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
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2X1G
 | | Crystal structure of Importin13 - Mago-Y14 complex | | Descriptor: | CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A | | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | | Deposit date: | 2009-12-23 | | Release date: | 2010-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
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2X19
 | | Crystal structure of Importin13 - RanGTP complex | | Descriptor: | GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ... | | Authors: | Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E. | | Deposit date: | 2009-12-23 | | Release date: | 2010-02-16 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | Authors: | Basquin, J, Oezguer, S, Conti, E. | | Deposit date: | 2015-09-08 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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5AOR
 | | Structure of MLE RNA ADP AlF4 complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | Authors: | Prabu, J.R, Conti, E. | | Deposit date: | 2015-09-11 | | Release date: | 2015-11-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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2XB2
 | | Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery | | Descriptor: | EUKARYOTIC INITIATION FACTOR 4A-III, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Buchwald, G, Ebert, J, Basquin, C, Sauliere, J, Jayachandran, U, Bono, F, Le Hir, H, Conti, E. | | Deposit date: | 2010-04-03 | | Release date: | 2010-05-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1JN5
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor | | Descriptor: | FG-repeat, TAP, p15 | | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | Deposit date: | 2001-07-23 | | Release date: | 2001-10-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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1JKG
 | | Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor | | Descriptor: | TAP, p15 | | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | | Deposit date: | 2001-07-12 | | Release date: | 2001-10-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
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2HWX
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2HWW
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2HWY
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2J0U
 | | The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution | | Descriptor: | ATP-DEPENDENT RNA HELICASE DDX48, PROTEIN CASC3 | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2J0S
 | | The crystal structure of the Exon Junction Complex at 2.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2J0Q
 | | The crystal structure of the Exon Junction Complex at 3.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-08-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
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2JEA
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2JEB
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2JE6
 | | Structure of a 9-subunit archaeal exosome | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, EXOSOME COMPLEX EXONUCLEASE 1, ... | | Authors: | Lorentzen, E, Conti, E. | | Deposit date: | 2007-01-15 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | RNA Channelling by the Archaeal Exosome.
Embo Rep., 8, 2007
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2JA9
 | | Structure of the N-terminal deletion of yeast exosome component Rrp40 | | Descriptor: | EXOSOME COMPLEX EXONUCLEASE RRP40 | | Authors: | Oddone, A, Lorentzen, E, Basquin, J, Gasch, A, Rybin, V, Conti, E, Sattler, M. | | Deposit date: | 2006-11-24 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40
Embo Rep., 8, 2007
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4AJ5
 | | Crystal structure of the Ska core complex | | Descriptor: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3 | | Authors: | Jeyaprakash, A.A, Santamaria, A, Jayachandran, U, Chan, Y.W, Benda, C, Nigg, E.A, Conti, E. | | Deposit date: | 2012-02-15 | | Release date: | 2012-05-23 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface.
Mol.Cell, 46, 2012
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4A4K
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4A6Q
 | | Crystal structure of mouse SAP18 residues 6-143 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, ISOPROPYL ALCOHOL | | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | | Deposit date: | 2011-11-08 | | Release date: | 2012-03-07 | | Last modified: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
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4A4Z
 | | CRYSTAL STRUCTURE OF THE S. CEREVISIAE DEXH HELICASE SKI2 BOUND TO AMPPNP | | Descriptor: | 1,2-ETHANEDIOL, ANTIVIRAL HELICASE SKI2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Halbach, F, Rode, M, Conti, E. | | Deposit date: | 2011-10-20 | | Release date: | 2011-12-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Crystal Structure of S. Cerevisiae Ski2, a Dexh Helicase Associated with the Cytoplasmic Functions of the Exosome.
RNA, 18, 2012
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4A90
 | | Crystal structure of mouse SAP18 residues 1-143 | | Descriptor: | GLYCEROL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 | | Authors: | Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E. | | Deposit date: | 2011-11-22 | | Release date: | 2012-03-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
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