4ONG
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![BU of 4ong by Molmil](/molmil-images/mine/4ong) | Fab fragment of 3D6 in complex with amyloid beta 1-40 | Descriptor: | 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ... | Authors: | Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S. | Deposit date: | 2014-01-28 | Release date: | 2014-06-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab. Alzheimers Res Ther, 6, 2014
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4JFI
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![BU of 4jfi by Molmil](/molmil-images/mine/4jfi) | Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione | Descriptor: | 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Wang, Y, Kirschner, A, Fabian, A, Gopalakrishnan, R, Kress, C, Hoogeland, B, Koch, U, Kozany, C, Bracher, A, Hausch, F. | Deposit date: | 2013-02-28 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J.Med.Chem., 56, 2013
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4OHZ
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![BU of 4ohz by Molmil](/molmil-images/mine/4ohz) | bound to ssRNA tetranucleotide GAAA, ADP, and Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | Deposit date: | 2014-01-18 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
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3A9K
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![BU of 3a9k by Molmil](/molmil-images/mine/3a9k) | Crystal structure of the mouse TAB3-NZF in complex with Lys63-linked di-ubiquitin | Descriptor: | Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, Ubiquitin, ZINC ION | Authors: | Sato, Y, Yoshikawa, A, Yamashita, M, Yamagata, A, Fukai, S. | Deposit date: | 2009-10-29 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3 Embo J., 28, 2009
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3AEF
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![BU of 3aef by Molmil](/molmil-images/mine/3aef) | Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | Deposit date: | 2010-02-04 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket To be Published
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3TIN
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![BU of 3tin by Molmil](/molmil-images/mine/3tin) | Tubulin tyrosine ligase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ttl protein | Authors: | Roll-Mecak, A, Szyk, A, Deaconescu, A, Piszczek, G. | Deposit date: | 2011-08-20 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin. Nat.Struct.Mol.Biol., 18, 2011
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2QFD
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![BU of 2qfd by Molmil](/molmil-images/mine/2qfd) | Crystal structure of the regulatory domain of human RIG-I with bound Hg | Descriptor: | MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58 | Authors: | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | Deposit date: | 2007-06-27 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29, 2008
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1PKY
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![BU of 1pky by Molmil](/molmil-images/mine/1pky) | PYRUVATE KINASE FROM E. COLI IN THE T-STATE | Descriptor: | PYRUVATE KINASE | Authors: | Mattevi, A. | Deposit date: | 1995-04-27 | Release date: | 1995-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition. Structure, 3, 1995
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3AE6
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![BU of 3ae6 by Molmil](/molmil-images/mine/3ae6) | Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid | Descriptor: | 2-{[3-(1-methylethoxy)phenyl]carbamoyl}benzoic acid, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | Deposit date: | 2010-02-04 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid To be Published
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4TY7
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![BU of 4ty7 by Molmil](/molmil-images/mine/4ty7) | |
3D1P
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![BU of 3d1p by Molmil](/molmil-images/mine/3d1p) | Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae | Descriptor: | ACETATE ION, CHLORIDE ION, Putative thiosulfate sulfurtransferase YOR285W | Authors: | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-05-06 | Release date: | 2008-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae. To be Published
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1WKX
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![BU of 1wkx by Molmil](/molmil-images/mine/1wkx) | |
2G5X
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![BU of 2g5x by Molmil](/molmil-images/mine/2g5x) | Crystal structure of lychnin a type 1 Ribosome Inactivating Protein (RIP) | Descriptor: | Ribosome-inactivating protein | Authors: | Fermani, S, Falini, G, Tosi, G, Ripamonti, A, Polito, L, Bolognesi, A, Stirpe, F. | Deposit date: | 2006-02-23 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of lychnin a type 1 Ribosome Inactivating Protein (RIP) To be Published
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2YAW
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![BU of 2yaw by Molmil](/molmil-images/mine/2yaw) | HG INHIBITED SULFUR OXYGENASE REDUCTASE | Descriptor: | ACETATE ION, FE (III) ION, MERCURY (II) ION, ... | Authors: | Veith, A, Urich, T, Seyfarth, K, Protze, J, Frazao, C, Kletzin, A. | Deposit date: | 2011-02-25 | Release date: | 2011-12-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Substrate Pathways and Mechanisms of Inhibition in the Sulfur Oxygenase Reductase of Acidianus Ambivalens. Front.Microbiol., 2, 2011
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3PWB
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![BU of 3pwb by Molmil](/molmil-images/mine/3pwb) | Bovine trypsin variant X(tripleGlu217Ile227) in complex with small molecule inhibitor | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | Deposit date: | 2010-12-08 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
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3D6W
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![BU of 3d6w by Molmil](/molmil-images/mine/3d6w) | LytTr DNA-binding domain of putative methyl-accepting/DNA response regulator from Bacillus cereus. | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Osipiuk, J, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-05-20 | Release date: | 2008-07-15 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray crystal structure of LytTr DNA-binding domain of putative methyl-accepting/DNA response regulator from Bacillus cereus. To be Published
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3CG9
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![BU of 3cg9 by Molmil](/molmil-images/mine/3cg9) | Crystal structure of the complex of peptidoglycan recognition protein with methyloxane-2,3,4,5-tetrol at 2.9 A resolution | Descriptor: | L(+)-TARTARIC ACID, Peptidoglycan recognition protein, alpha-L-rhamnopyranose | Authors: | Sharma, P, Kaur, A, Singh, N, Sharma, S, Bhushan, A, Pathak, K.M.L, Kaur, P, Singh, T.P. | Deposit date: | 2008-03-05 | Release date: | 2008-04-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the complex of peptidoglycan recognition protein with methyoxane-2,3,4,5-tetrol at 2.9 A resolution To be Published
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3CNG
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![BU of 3cng by Molmil](/molmil-images/mine/3cng) | Crystal structure of NUDIX hydrolase from Nitrosomonas europaea | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Osipiuk, J, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-25 | Release date: | 2008-04-08 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of NUDIX hydrolase from Nitrosomonas europaea. To be Published
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3CP8
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![BU of 3cp8 by Molmil](/molmil-images/mine/3cp8) | Crystal structure of GidA from Chlorobium tepidum | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA | Authors: | Meyer, S, Scrima, A, Versees, W, Wittinghofer, A. | Deposit date: | 2008-03-31 | Release date: | 2008-06-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate J.Mol.Biol., 380, 2008
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4B1L
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![BU of 4b1l by Molmil](/molmil-images/mine/4b1l) | CARBOHYDRATE BINDING MODULE CBM66 FROM BACILLUS SUBTILIS | Descriptor: | LEVANASE, SODIUM ION, beta-D-fructofuranose | Authors: | Cuskin, F, Flint, J.E, Morland, C, Basle, A, Henrissat, B, Countinho, P.M, Strazzulli, A, Solzehinkin, A, Davies, G.J, Gilbert, H.J, Gloster, T.M. | Deposit date: | 2012-07-11 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | How Nature Can Exploit Nonspecific Catalytic and Carbohydrate Binding Modules to Create Enzymatic Specificity Proc.Natl.Acad.Sci.USA, 109, 2012
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2EFL
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![BU of 2efl by Molmil](/molmil-images/mine/2efl) | Crystal structure of the EFC domain of formin-binding protein 17 | Descriptor: | Formin-binding protein 1 | Authors: | Shimada, A, Niwa, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2007-05-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis Cell(Cambridge,Mass.), 129, 2007
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3CEI
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![BU of 3cei by Molmil](/molmil-images/mine/3cei) | Crystal Structure of Superoxide Dismutase from Helicobacter pylori | Descriptor: | FE (III) ION, SULFATE ION, Superoxide dismutase | Authors: | Esposito, L, Seydel, A, Aiello, R, Sorrentino, G, Cendron, L, Zanotti, G, Zagari, A. | Deposit date: | 2008-02-29 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension Biochim.Biophys.Acta, 1784, 2008
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2PDH
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![BU of 2pdh by Molmil](/molmil-images/mine/2pdh) | Human aldose reductase mutant L300P complexed with uracil-type inhibitor at 1.45 A. | Descriptor: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID | Authors: | Steuber, H, Heine, A, Klebe, G. | Deposit date: | 2007-03-31 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J.Mol.Biol., 379, 2008
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3CPI
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![BU of 3cpi by Molmil](/molmil-images/mine/3cpi) | Crystal structure of yeast Rab-GDI | Descriptor: | Rab GDP-dissociation inhibitor | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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1QM7
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![BU of 1qm7 by Molmil](/molmil-images/mine/1qm7) | X-ray structure of a three-fingered chimeric protein, stability of a structural scaffold | Descriptor: | R-CHII | Authors: | Le Du, M.H, Ricciardi, A, Khayati, M, Menez, R, Boulain, J.C, Menez, A, Ducancel, F. | Deposit date: | 1999-09-21 | Release date: | 2000-03-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Stability of a Structural Scaffold Upon Activity Transfer : X-Ray Structure of a Three Fingers Chimeric Protein. J.Mol.Biol., 296, 2000
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