7XR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xr5 by Molmil](/molmil-images/mine/7xr5) | Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, J, Chen, R.C, Gao, S.S. | Deposit date: | 2022-05-09 | Release date: | 2022-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Actinomycetes-derived imine reductases with a preference towards bulky amine substrates. Commun Chem, 5, 2022
|
|
6GKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gks by Molmil](/molmil-images/mine/6gks) | |
6GKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gkq by Molmil](/molmil-images/mine/6gkq) | |
1KJU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kju by Molmil](/molmil-images/mine/1kju) | Ca2+-ATPase in the E2 State | Descriptor: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1a | Authors: | Xu, C, Rice, W.J, He, W, Stokes, D.L. | Deposit date: | 2001-12-05 | Release date: | 2001-12-19 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | A structural model for the catalytic cycle of Ca(2+)-ATPase. J.Mol.Biol., 316, 2002
|
|
6GKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gku by Molmil](/molmil-images/mine/6gku) | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5 | Descriptor: | CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ... | Authors: | Verstraete, K, Verschueren, K, Savvides, S.N. | Deposit date: | 2018-05-21 | Release date: | 2019-06-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
|
|
5GSK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gsk by Molmil](/molmil-images/mine/5gsk) | Crystal structure of duplex DNA3 in complex with Hg(II) and Sr(II) | Descriptor: | DNA (5'-D(*GP*GP*TP*CP*GP*TP*CP*C)-3'), MERCURY (II) ION, STRONTIUM ION | Authors: | Liu, H.H, Wang, R, Yao, Q.Q, Cheng, Y.Q, Yang, C, Luo, Q, Wu, B.X, Li, J.X, Ma, J.B, Sheng, J, Gan, J.H. | Deposit date: | 2016-08-16 | Release date: | 2017-02-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex Nucleic Acids Res., 45, 2017
|
|
6LXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lxg by Molmil](/molmil-images/mine/6lxg) | NMR solution structure of regulatory ACT domain of the Mycobacterium tuberculosis Rel protein | Descriptor: | GTP pyrophosphokinase | Authors: | Shin, J, Singal, B, Manimekalai, M.S.S, Gruber, G. | Deposit date: | 2020-02-11 | Release date: | 2020-11-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein. Febs J., 288, 2021
|
|
5E1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e1q by Molmil](/molmil-images/mine/5e1q) | Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac | Descriptor: | CALCIUM ION, GLYCEROL, Retaining alpha-galactosidase, ... | Authors: | Matsunaga, K, Yamashita, K, Tagami, T, Yao, M, Okuyama, M, Kimura, A. | Deposit date: | 2015-09-30 | Release date: | 2016-10-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.943 Å) | Cite: | Efficient synthesis of alpha-galactosyl oligosaccharides using a mutant Bacteroides thetaiotaomicron retaining alpha-galactosidase (BtGH97b). FEBS J., 284, 2017
|
|
3QSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qsu by Molmil](/molmil-images/mine/3qsu) | |
5TZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tzb by Molmil](/molmil-images/mine/5tzb) | Burkholderia sp. beta-aminopeptidase | Descriptor: | CALCIUM ION, D-aminopeptidase | Authors: | McGowan, S, Drinkwater, N, John, M, Dumsday, G. | Deposit date: | 2016-11-21 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.977 Å) | Cite: | Crystal structure of a beta-aminopeptidase from an Australian Burkholderia sp. Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
6N1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n1g by Molmil](/molmil-images/mine/6n1g) | |
2ZHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zhx by Molmil](/molmil-images/mine/2zhx) | Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor | Descriptor: | Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor | Authors: | Kaushal, P.S, Talawar, R.K, Krishna, P.D.V, Varshney, U, Vijayan, M. | Deposit date: | 2008-02-11 | Release date: | 2008-05-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources Acta Crystallogr.,Sect.D, 64, 2008
|
|
3NTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nte by Molmil](/molmil-images/mine/3nte) | |
5V5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v5d by Molmil](/molmil-images/mine/5v5d) | Room temperature (280K) crystal structure of Kaposi's sarcoma-associated herpesvirus protease in complex with allosteric inhibitor (compound 250) | Descriptor: | 4-{[6-(cyclohexylmethyl)pyridine-2-carbonyl]amino}-3-(phenylamino)benzoic acid, ORF 17 | Authors: | Thompson, M.C, Acker, T.M, Fraser, J.S, Craik, C.S. | Deposit date: | 2017-03-14 | Release date: | 2017-04-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases. J. Am. Chem. Soc., 139, 2017
|
|
3A7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a7n by Molmil](/molmil-images/mine/3a7n) | Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis | Descriptor: | CITRATE ANION, Uracil-DNA glycosylase | Authors: | Kaushal, P.S, Talawar, R.K, Varshney, U, Vijayan, M. | Deposit date: | 2009-09-29 | Release date: | 2010-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands Acta Crystallogr.,Sect.F, 66, 2010
|
|
5V5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v5e by Molmil](/molmil-images/mine/5v5e) | Room temperature (280K) crystal structure of Kaposi's sarcoma-associated herpesvirus protease in complex with allosteric inhibitor (compound 733) | Descriptor: | 4-{[6-(cyclohexylmethyl)pyridine-2-carbonyl]amino}-3-{[3-(trifluoromethoxy)phenyl]amino}benzoic acid, ORF 17 | Authors: | Thompson, M.C, Acker, T.M, Fraser, J.S, Craik, C.S. | Deposit date: | 2017-03-14 | Release date: | 2017-04-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases. J. Am. Chem. Soc., 139, 2017
|
|
3P8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3p8z by Molmil](/molmil-images/mine/3p8z) | Dengue Methyltransferase bound to a SAM-based inhibitor | Descriptor: | (S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid, Non-structural protein 5, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Noble, C.G, Yap, L.J, Lescar, J. | Deposit date: | 2010-10-15 | Release date: | 2010-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Small molecule inhibitors that selectively block dengue virus methyltransferase J.Biol.Chem., 286, 2011
|
|
3P97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3p97 by Molmil](/molmil-images/mine/3p97) | |
4GAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gax by Molmil](/molmil-images/mine/4gax) | Crystal Structure of an alpha-Bisabolol synthase mutant | Descriptor: | Amorpha-4,11-diene synthase | Authors: | Li, J, Peng, Z. | Deposit date: | 2012-07-26 | Release date: | 2013-03-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9948 Å) | Cite: | Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochem.J., 451, 2013
|
|
3LN9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ln9 by Molmil](/molmil-images/mine/3ln9) | Crystal structure of the fibril-specific B10 antibody fragment | Descriptor: | CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ... | Authors: | Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M. | Deposit date: | 2010-02-02 | Release date: | 2010-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions. J.Mol.Biol., 2010
|
|
3HD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hd3 by Molmil](/molmil-images/mine/3hd3) | High resolution crystal structure of cruzain bound to the vinyl sulfone inhibitor SMDC-256047 | Descriptor: | (1R,2R)-2-[(4-chlorophenyl)carbonyl]-N-{(1S)-1-[2-(phenylsulfonyl)ethyl]pentyl}cyclohexanecarboxamide, 1,2-ETHANEDIOL, Cruzipain, ... | Authors: | Kerr, I.D, Debnath, M, Brinen, L.S. | Deposit date: | 2009-05-06 | Release date: | 2009-10-06 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg.Med.Chem.Lett., 19, 2009
|
|
1L2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1l2e by Molmil](/molmil-images/mine/1l2e) | Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor | Descriptor: | BENZAMIDINE, Kallikrein 6, MAGNESIUM ION | Authors: | Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Blaber, M. | Deposit date: | 2002-02-20 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J.Biol.Chem., 277, 2002
|
|
1GSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gsq by Molmil](/molmil-images/mine/1gsq) | THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS | Descriptor: | GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE | Authors: | Ji, X, Rosenvinge, E.C.V, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1995-01-09 | Release date: | 1995-06-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry, 34, 1995
|
|
4FJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fjq by Molmil](/molmil-images/mine/4fjq) | Crystal Structure of an alpha-Bisabolol synthase | Descriptor: | Amorpha-4,11-diene synthase | Authors: | Jianxu, L, Peng, Z. | Deposit date: | 2012-06-12 | Release date: | 2013-03-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0001 Å) | Cite: | Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochem.J., 451, 2013
|
|
3CC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cc2 by Molmil](/molmil-images/mine/3cc2) | |