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8XZG
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BU of 8xzg by Molmil
Cryo-EM structure of the [Pyr1]-apelin-13-bound human APLNR-Gi complex
Descriptor: Apelin receptor, Apelin-13, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, W, Ji, S, Zhang, Y.
Deposit date:2024-01-21
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
6AD0
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BU of 6ad0 by Molmil
The structure of CVA10 mature virion in complex with Fab 2G8
Descriptor: SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ...
Authors:Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-28
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AJ0
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BU of 6aj0 by Molmil
The structure of Enterovirus D68 mature virion
Descriptor: Capsid protein VP3, Capsid protein VP4, Viral protein 1, ...
Authors:Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W.
Deposit date:2018-08-25
Release date:2018-11-07
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
8XZF
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BU of 8xzf by Molmil
Cryo-EM structure of the WN561-bound human APLNR-Gi complex
Descriptor: Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, W, Ji, S, Zhang, Y.
Deposit date:2024-01-21
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
8XZJ
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BU of 8xzj by Molmil
Cryo-EM structure of the WN353-bound human APLNR-Gi complex
Descriptor: Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, W, Ji, S, Zhang, Y.
Deposit date:2024-01-21
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
8XZI
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BU of 8xzi by Molmil
Cryo-EM structure of the CMF-019-bound human APLNR-Gi complex
Descriptor: (3~{S})-5-methyl-3-[[1-pentan-3-yl-2-(thiophen-2-ylmethyl)benzimidazol-5-yl]carbonylamino]hexanoic acid, Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, W, Ji, S, Zhang, Y.
Deposit date:2024-01-21
Release date:2024-03-20
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
8XZH
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BU of 8xzh by Molmil
Cryo-EM structure of the MM07-bound human APLNR-Gi complex
Descriptor: Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, W, Ji, S, Zhang, Y.
Deposit date:2024-01-21
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
6AJ9
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BU of 6aj9 by Molmil
The structure of Enterovirus D68 mature virion in complex with Fab 15C5 and 11G1
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W.
Deposit date:2018-08-27
Release date:2018-11-07
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6ACZ
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BU of 6acz by Molmil
The structure of CVA10 virus A-particle from its complex with Fab 2G8
Descriptor: VP1, VP2, VP3
Authors:Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-28
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AJ3
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BU of 6aj3 by Molmil
The structure of Enterovirus D68 procapsid
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
Authors:Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W.
Deposit date:2018-08-26
Release date:2018-11-07
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6AJ7
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BU of 6aj7 by Molmil
The structure of Enterovirus D68 mature virion in complex with Fab 15C5
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W.
Deposit date:2018-08-27
Release date:2018-11-07
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
6ACY
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BU of 6acy by Molmil
The structure of CVA10 virus A-particle
Descriptor: VP1, VP2, VP3
Authors:Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
Deposit date:2018-07-28
Release date:2018-11-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6LGN
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BU of 6lgn by Molmil
The atomic structure of varicella zoster virus C-capsid
Descriptor: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Li, S, Zheng, Q.
Deposit date:2019-12-05
Release date:2020-07-29
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids.
Nat Microbiol, 5, 2020
6OVG
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BU of 6ovg by Molmil
L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism
Descriptor: Cystathionine gamma-lyase, SULFATE ION
Authors:Yan, W, Irani, S, Zhang, J.
Deposit date:2019-05-07
Release date:2020-04-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.719 Å)
Cite:Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LGL
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BU of 6lgl by Molmil
The atomic structure of varicella-zoster virus A-capsid
Descriptor: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
Authors:Zheng, Q, Li, S.
Deposit date:2019-12-05
Release date:2020-07-29
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids.
Nat Microbiol, 5, 2020
8TQD
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BU of 8tqd by Molmil
NF-Kappa-B1 Bound with a Covalent Inhibitor
Descriptor: 1-(2-bromo-4-chlorophenyl)-N-{(3S)-1-[(E)-iminomethyl]pyrrolidin-3-yl}methanesulfonamide, Nuclear factor NF-kappa-B p105 subunit
Authors:Hilbert, B.J.
Deposit date:2023-08-07
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Cell, 187, 2024
6C0B
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BU of 6c0b by Molmil
Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-2, MALONATE ION, ...
Authors:Chen, P, Lam, K, Jin, R.
Deposit date:2017-12-28
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of frizzled proteins byClostridium difficiletoxin B.
Science, 360, 2018
8KHD
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BU of 8khd by Molmil
The interface structure of Omicron RBD binding to 5817 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817, Light chain of 5817, ...
Authors:Cao, L, Wang, X.
Deposit date:2023-08-21
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8KHC
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BU of 8khc by Molmil
SARS-CoV-2 Omicron spike in complex with 5817 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ...
Authors:Cao, L, Wang, X.
Deposit date:2023-08-21
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
6CNA
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BU of 6cna by Molmil
GluN1-GluN2B NMDA receptors with exon 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Furukawa, H, Grant, T, Grigorieff, N.
Deposit date:2018-03-07
Release date:2018-10-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
3B5H
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BU of 3b5h by Molmil
Crystal structure of the extracellular portion of HAb18G/CD147
Descriptor: ACETATE ION, Cervical EMMPRIN
Authors:Yu, X.-L, Chen, Z.-N.
Deposit date:2007-10-26
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion.
J.Biol.Chem., 283, 2008
7VW9
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BU of 7vw9 by Molmil
Helicoverpa armigera pheromone-binding protein PBP1 at pH 5.5
Descriptor: PBP1
Authors:Zheng, J, Chen, Z.
Deposit date:2021-11-10
Release date:2022-02-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7VWA
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BU of 7vwa by Molmil
Helicoverpa armigera pheromone-binding protein PBP1 with Z-9-hexadecenal
Descriptor: (Z)-hexadec-9-enal, PBP1
Authors:Zheng, J, Chen, Z.
Deposit date:2021-11-10
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7VW8
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BU of 7vw8 by Molmil
Helicoverpa armigera pheromone-binding protein PBP1 at pH 7.5
Descriptor: PBP1
Authors:Zheng, J, Chen, Z.
Deposit date:2021-11-09
Release date:2022-02-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
2L83
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BU of 2l83 by Molmil
A protein from Haloferax volcanii
Descriptor: Small archaeal modifier protein 1
Authors:Zhang, W, Liao, S, Fan, K, Tu, X.
Deposit date:2011-01-03
Release date:2012-01-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ionic strength-dependent conformations of a ubiquitin-like small archaeal modifier protein (SAMP1) from Haloferax volcanii.
Protein Sci., 22, 2013

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數據於2024-10-16公開中

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