1LNT
 
 | | Crystal Structure of the Highly Conserved RNA Internal Loop of SRP | | Descriptor: | 5'-R(*CP*GP*GP*AP*AP*GP*CP*AP*GP*(CBV)P*GP*C)-3', 5'-R(*GP*CP*GP*UP*CP*AP*GP*GP*UP*CP*(CBV)P*G)-3', CALCIUM ION, ... | | Authors: | Deng, J, Xiong, Y, Pan, B, Sundaralingam, M. | | Deposit date: | 2002-05-03 | | Release date: | 2003-06-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of an RNA dodecamer containing a fragment from SRP domain IV of Escherichia coli.
Acta Crystallogr.,Sect.D, 59, 2003
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1MIW
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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1MDG
 | | An Alternating Antiparallel Octaplex in an RNA Crystal Structure | | Descriptor: | 5'-R(*UP*(BGM)GP*AP*GP*GP*U)-3', COBALT HEXAMMINE(III), SODIUM ION | | Authors: | Pan, B.C, Xiong, Y, Shi, K, Sundaralingam, M. | | Deposit date: | 2002-08-07 | | Release date: | 2003-08-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | An Eight-Stranded Helical Fragment in RNA Crystal Structure: Implications for Tetraplex Interaction
Structure, 11, 2003
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1MIY
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with CTP | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.52 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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7LUG
 | | Crystal structure of the pnRFP B30Y mutant | | Descriptor: | PHOSPHATE ION, Red Fluorescent pnRFP B30Y mutant | | Authors: | Huang, M, Ng, H.L, Pang, Y, Zhang, S, Fan, Y, Yeh, H, Xiong, Y, Li, X, Ai, H. | | Deposit date: | 2021-02-22 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Development, Characterization, and Structural Analysis of a Genetically Encoded Red Fluorescent Peroxynitrite Biosensor
To Be Published
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7LQO
 | | Crystal structure of a genetically encoded red fluorescent peroxynitrite biosensor, pnRFP | | Descriptor: | PHOSPHATE ION, red fluorescent peroxynitrite biosensor pnRFP | | Authors: | Huang, M, Ng, H.L, Pang, Y, Zhang, S, Fan, Y, Yeh, H, Xiong, Y, Li, X, Ai, H. | | Deposit date: | 2021-02-14 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Development, Characterization, and Structural Analysis of a Genetically Encoded Red Fluorescent Peroxynitrite Biosensor
To Be Published
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1NA3
 | | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | | Authors: | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | | Deposit date: | 2002-11-26 | | Release date: | 2003-06-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
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1NA0
 | | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, ACETATE ION, CHLORIDE ION, ... | | Authors: | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | | Deposit date: | 2002-11-26 | | Release date: | 2003-06-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
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1MIV
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme | | Descriptor: | MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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1P79
 | | Crystal structure of a bulged RNA tetraplex: implications for a novel binding site in RNA tetraplex | | Descriptor: | 5'-R(*UP*GP*UP*GP*GP*U)-3', POTASSIUM ION | | Authors: | Pan, B, Xiong, Y, Shi, K, Sundaralingam, M. | | Deposit date: | 2003-04-30 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Crystal Structure of a Bulged RNA Tetraplex at 1.1 A Resolution: Implications for a Novel Binding Site in RNA Tetraplex
STRUCTURE, 11, 2003
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9D6E
 | | Gag CA-SP1 immature lattice bound with Bevirimat from enveloped virus like particles | | Descriptor: | 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | | Authors: | Wu, C, Meuser, M.E, Xiong, Y. | | Deposit date: | 2024-08-14 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM.
Biorxiv, 2024
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9DWD
 | | Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles (T8I) | | Descriptor: | Gag, INOSITOL HEXAKISPHOSPHATE, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide | | Authors: | Wu, C, Meuser, M.E, Xiong, Y. | | Deposit date: | 2024-10-09 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM.
Biorxiv, 2024
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9D6C
 | | Gag CA-SP1 immature lattice bound with Lenacapavir and Bevirimat from enveloped virus like particles | | Descriptor: | 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Wu, C, Meuser, M.E, Xiong, Y. | | Deposit date: | 2024-08-14 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM.
Biorxiv, 2024
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9CWV
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9D6D
 | | Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles | | Descriptor: | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide | | Authors: | Wu, C, Meuser, M.E, Xiong, Y. | | Deposit date: | 2024-08-14 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.18 Å) | | Cite: | Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM.
Biorxiv, 2024
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9D88
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1YQY
 | | Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor | | Descriptor: | (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE, Lethal factor, ZINC ION | | Authors: | Shoop, W.L, Xiong, Y, Wiltsie, J, Woods, A, Guo, J, Pivnichny, J.V, Felcetto, T, Michael, B.F, Bansal, A. | | Deposit date: | 2005-02-02 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Anthrax lethal factor inhibition.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ZR2
 | | Structure of a Synaptic gamma-delta Resolvase Tetramer Covalently Linked to two Cleaved DNAs | | Descriptor: | AAA, TCAGTGTCCGATAATTTAT, TTATCGGACACTG, ... | | Authors: | Li, W, Kamtekar, S, Xiong, Y, Sarkis, G.J, Grindley, N.D, Steitz, T.A. | | Deposit date: | 2005-05-18 | | Release date: | 2005-08-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structure of a synaptic gamma delta resolvase tetramer covalently linked to two cleaved DNAs.
Science, 309, 2005
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1ZR4
 | | Structure of a Synaptic gamma-delta Resolvase Tetramer Covalently linked to two Cleaved DNAs | | Descriptor: | AAA, TCAGTGTCCGATAATTTAT, TTATCGGACACTG, ... | | Authors: | Li, W, Kamtekar, S, Xiong, Y, Sarkis, G.J, Grindley, N.D, Steitz, T.A. | | Deposit date: | 2005-05-19 | | Release date: | 2005-08-30 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure of a synaptic gamma delta resolvase tetramer covalently linked to two cleaved DNAs.
Science, 309, 2005
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4EMZ
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4EN2
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7UKN
 | | Crystal Structure of DDB1 in Complex with the H-Box Motif of pUL145 | | Descriptor: | DNA damage-binding protein 1, H-Box Motif of pUL145 | | Authors: | Wick, E.T, Treadway, C.J, Nicely, N.I, Li, Z, Ren, Z, Baldwin, A.S, Xiong, Y, Harrison, J.S, Brown, N.G. | | Deposit date: | 2022-04-01 | | Release date: | 2022-08-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex.
J.Virol., 96, 2022
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4NE6
 | | Human MHF1-MHF2 complex | | Descriptor: | Centromere protein S, Centromere protein X | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2013-12-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.1001 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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4NE5
 | | Human MHF1-MHF2 complex | | Descriptor: | Centromere protein S, Centromere protein X | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2013-12-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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4NE1
 | | Human MHF1 MHF2 DNA complexes | | Descriptor: | Centromere protein S, Centromere protein X, DNA (26-MER) | | Authors: | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | | Deposit date: | 2013-10-28 | | Release date: | 2014-01-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (6.499 Å) | | Cite: | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
Nat Commun, 5, 2014
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