Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4QXC
DownloadVisualize
BU of 4qxc by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME2 with NOG
Descriptor: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2014-07-19
Release date:2014-11-05
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXB
DownloadVisualize
BU of 4qxb by Molmil
crystal structure of histone demethylase KDM2A-H3K36ME3 with NOG
Descriptor: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2014-07-19
Release date:2014-11-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QWN
DownloadVisualize
BU of 4qwn by Molmil
Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure
Descriptor: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2014-07-16
Release date:2014-11-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
6OP6
DownloadVisualize
BU of 6op6 by Molmil
Structure of VIM-20 in the reduced state
Descriptor: Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION
Authors:Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
Deposit date:2019-04-24
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
6OP7
DownloadVisualize
BU of 6op7 by Molmil
Structure of oxidized VIM-20
Descriptor: ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION
Authors:Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
Deposit date:2019-04-24
Release date:2019-10-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
6CDX
DownloadVisualize
BU of 6cdx by Molmil
High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin
Descriptor: cystine knot (fluoropropylated)
Authors:Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V.
Deposit date:2018-02-09
Release date:2019-08-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1 Å)
Cite:Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.
Nat Commun, 10, 2019
6J6M
DownloadVisualize
BU of 6j6m by Molmil
Co-crystal structure of BTK kinase domain with Zanubrutinib
Descriptor: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK
Authors:Zhou, X, Hong, Y.
Deposit date:2019-01-15
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
2XUE
DownloadVisualize
BU of 2xue by Molmil
CRYSTAL STRUCTURE OF JMJD3
Descriptor: 2-OXOGLUTARIC ACID, FE (III) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
Authors:Chung, C, Rowland, P, Mosley, J, Thomas, P.J.
Deposit date:2010-10-19
Release date:2011-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488, 2012
4EZH
DownloadVisualize
BU of 4ezh by Molmil
the crystal structure of KDM6B bound with H3K27me3 peptide
Descriptor: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2012-05-02
Release date:2012-08-08
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
4EYU
DownloadVisualize
BU of 4eyu by Molmil
The free structure of the mouse C-terminal domain of KDM6B
Descriptor: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2012-05-01
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
4EZ4
DownloadVisualize
BU of 4ez4 by Molmil
free KDM6B structure
Descriptor: Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2012-05-02
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
1YFK
DownloadVisualize
BU of 1yfk by Molmil
Crystal structure of human B type phosphoglycerate mutase
Descriptor: CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1
Authors:Wang, Y, Wei, Z, Liu, L, Gong, W.
Deposit date:2005-01-02
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human B-type phosphoglycerate mutase bound with citrate.
Biochem.Biophys.Res.Commun., 331, 2005
1RZ4
DownloadVisualize
BU of 1rz4 by Molmil
Crystal Structure of Human eIF3k
Descriptor: Eukaryotic translation initiation factor 3 subunit 11, SULFATE ION
Authors:Wei, Z, Zhang, P, Zhou, Z, Gong, W.
Deposit date:2003-12-23
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human eIF3k, the first structure of eIF3 subunits
J.Biol.Chem., 279, 2004
4ASK
DownloadVisualize
BU of 4ask by Molmil
CRYSTAL STRUCTURE OF JMJD3 WITH GSK-J1
Descriptor: 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, COBALT (II) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
Authors:Chung, C, Mosley, J, Liddle, J.
Deposit date:2012-05-01
Release date:2012-07-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488, 2012
4A3N
DownloadVisualize
BU of 4a3n by Molmil
Crystal Structure of HMG-BOX of Human SOX17
Descriptor: TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N, Gao, H, Qian, H, Si, S, Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
1YJX
DownloadVisualize
BU of 1yjx by Molmil
Crystal structure of human B type phosphoglycerate mutase
Descriptor: CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1
Authors:Wang, Y, Wei, Z, Liu, L, Gong, W.
Deposit date:2005-01-16
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human B-type phosphoglycerate mutase bound with citrate.
Biochem.Biophys.Res.Commun., 331, 2005
1T2L
DownloadVisualize
BU of 1t2l by Molmil
Three Crystal Structures of Human Coactosin-like Protein
Descriptor: Coactosin-like protein
Authors:Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W.
Deposit date:2004-04-22
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Coactosin-like Protein
J.Mol.Biol., 344, 2004
2O0F
DownloadVisualize
BU of 2o0f by Molmil
Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3
Descriptor: Peptide chain release factor 3
Authors:Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H.
Deposit date:2006-11-27
Release date:2007-07-24
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2A9J
DownloadVisualize
BU of 2a9j by Molmil
Human bisphosphoglycerate mutase complexed with 3-phosphoglycerate (17 days)
Descriptor: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase
Authors:Wang, Y, Gong, W.
Deposit date:2005-07-11
Release date:2006-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
2KBE
DownloadVisualize
BU of 2kbe by Molmil
solution structure of amino-terminal domain of Dbp5p
Descriptor: ATP-dependent RNA helicase DBP5
Authors:Fan, J.S, Zhang, J, Yang, D.
Deposit date:2008-11-27
Release date:2009-10-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
2KBF
DownloadVisualize
BU of 2kbf by Molmil
solution structure of carboxyl-terminal domain of Dbp5p
Descriptor: ATP-dependent RNA helicase DBP5
Authors:Fan, J.S, Zhang, J, Yang, D.
Deposit date:2008-11-28
Release date:2009-10-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
2F90
DownloadVisualize
BU of 2f90 by Molmil
Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4-
Descriptor: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION
Authors:Wang, Y, Liu, L, Wei, Z, Gong, W.
Deposit date:2005-12-05
Release date:2006-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
8YLC
DownloadVisualize
BU of 8ylc by Molmil
The crystal structure of PDE4D with Amentoflavone
Descriptor: 3',5'-cyclic-AMP phosphodiesterase 4D, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ...
Authors:Huang, Y.-Y, Luo, H.-B.
Deposit date:2024-03-06
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.30003715 Å)
Cite:Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects
Chin.Chem.Lett., 2024
4XT9
DownloadVisualize
BU of 4xt9 by Molmil
RORgamma (263-509) complexed with GSK2435341A and SRC2
Descriptor: LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ...
Authors:Wang, Y, Ma, Y.
Deposit date:2015-01-23
Release date:2015-08-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
2H4Z
DownloadVisualize
BU of 2h4z by Molmil
Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate
Descriptor: (2R)-2,3-diphosphoglyceric acid, Bisphosphoglycerate mutase
Authors:Wang, Y, Gong, W.
Deposit date:2006-05-25
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase.
J.Biol.Chem., 281, 2006

221716

數據於2024-06-26公開中

PDB statisticsPDBj update infoContact PDBjnumon