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3HXU
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BU of 3hxu by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
2M38
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BU of 2m38 by Molmil
PTB domain of AIDA1
Descriptor: Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Authors:Donaldson, L.
Deposit date:2013-01-14
Release date:2013-01-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein.
Plos One, 8, 2013
3HXX
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BU of 3hxx by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP
Descriptor: Alanyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXW
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BU of 3hxw by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with SerSA
Descriptor: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
Authors:Guo, M, Yang, X.-L, Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
4EWH
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BU of 4ewh by Molmil
Co-crystal structure of ACK1 with inhibitor
Descriptor: 6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Activated CDC42 kinase 1
Authors:Liu, J, Walker, N, Wang, Z.
Deposit date:2012-04-27
Release date:2012-09-19
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
8EDO
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BU of 8edo by Molmil
Cryo-EM structure of the full-length human NF1 dimer
Descriptor: Neurofibromin
Authors:Darling, J.E, Merk, A, Grisshammer, R, Ognjenovic, J.
Deposit date:2022-09-05
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the full-length human NF1 dimer
To Be Published
8EDN
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BU of 8edn by Molmil
Cryo-EM structure of the full-length human NF1 dimer
Descriptor: Isoform I of Neurofibromin
Authors:Darling, J.E, Merk, A, Grisshammer, R, Ognjenovic, J.
Deposit date:2022-09-05
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the full-length human NF1 dimer
To Be Published
8EDL
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BU of 8edl by Molmil
Cryo-EM structure of the full-length human NF1 dimer
Descriptor: Isoform I of Neurofibromin
Authors:Darling, J.E, Merk, A, Grisshammer, R, Ognjenovic, J.
Deposit date:2022-09-05
Release date:2023-09-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the full-length human NF1 dimer
To Be Published
6SAI
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BU of 6sai by Molmil
NMR solution structure of Hml-2 C-terminal dimer domain
Descriptor: Gag protein
Authors:Nicastro, G, Taylor, I.A, Ball, N.J, Ramos, A.
Deposit date:2019-07-16
Release date:2020-01-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for Fullerene geometry in a human endogenous retrovirus capsid.
Nat Commun, 10, 2019
3RJZ
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BU of 3rjz by Molmil
X-ray crystal structure of the putative n-type atp pyrophosphatase from pyrococcus furiosus, the northeast structural genomics target pfr23
Descriptor: N-type ATP pyrophosphatase superfamily
Authors:Forouhar, F, Lee, I, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-04-16
Release date:2011-05-11
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Acta Crystallogr.,Sect.F, 67, 2011
1QIL
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BU of 1qil by Molmil
INACTIVE MUTANT TOXIC SHOCK SYNDROME TOXIN-1 AT 2.5 A
Descriptor: TOXIC SHOCK SYNDROME TOXIN-1
Authors:Acharya, K.R, Papageorgiou, A.C.
Deposit date:1997-03-27
Release date:1997-08-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a biologically inactive mutant of toxic shock syndrome toxin-1 at 2.5 A resolution.
Protein Sci., 5, 1996
5U5S
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BU of 5u5s by Molmil
Solution structures of Brd2 second bromodomain in complex with stat3 peptide
Descriptor: Bromodomain-containing protein 2, Stat3 peptide
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2016-12-07
Release date:2017-03-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Mol. Cell, 65, 2017
6B42
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BU of 6b42 by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) 2'-deoxy-AMP complex at 1.13A resolution
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
Authors:Maize, K.M, Finzel, B.C.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14, 2017
6B4C
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BU of 6b4c by Molmil
Structure of Viperin from Trichoderma virens
Descriptor: CITRATE ANION, SULFATE ION, Viperin
Authors:Huang, R.H, Selvadurai, K.
Deposit date:2017-09-26
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin.
J.Biol.Chem., 293, 2018
7W22
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BU of 7w22 by Molmil
Structure of the M. tuberculosis HtrA K436A mutant
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W23
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BU of 7w23 by Molmil
Structure of the M. tuberculosis HtrA S363A mutant
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W24
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BU of 7w24 by Molmil
Structure of the M. tuberculosis HtrA N383A mutant
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W25
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BU of 7w25 by Molmil
Structure of the M. tuberculosis HtrA S413A mutant
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W21
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BU of 7w21 by Molmil
Structure of the M. tuberculosis HtrA N269A mutant
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4R
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BU of 7w4r by Molmil
Structure of the M. tuberculosis HtrA N269A mutant at room-temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4W
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BU of 7w4w by Molmil
Structure of the M. tuberculosis HtrA K436A mutant at room-temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4T
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BU of 7w4t by Molmil
Structure of the M. tuberculosis HtrA S367A mutant at room-temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4S
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BU of 7w4s by Molmil
Structure of the M. tuberculosis HtrA S363A mutant at room-temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4U
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BU of 7w4u by Molmil
Structure of the M. tuberculosis HtrA S407A mutant at room-temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023
7W4V
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BU of 7w4v by Molmil
Structure of the M. tuberculosis HtrA S413A mutant at room temperature
Descriptor: Probable serine protease HtrA1
Authors:Gupta, A.K, Gopal, B.
Deposit date:2021-11-29
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allosteric Determinants in High Temperature Requirement A Enzymes Are Conserved and Regulate the Population of Active Conformations.
Acs Chem.Biol., 18, 2023

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數據於2024-07-24公開中

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