8EDN

Cryo-EM structure of the full-length human NF1 dimer

Summary for 8EDN

• Entry DOI: 10.2210/pdb8edn/pdb
• EMDB information: 28037
• Descriptor: Isoform I of Neurofibromin (1 entity in total)
• Functional Keywords: gtpase activating protein, ras signaling, cancer, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 317410.81

Authors

Darling, J.E.,Merk, A.,Grisshammer, R.,Ognjenovic, J. (deposition date: 2022-09-05, release date: 2023-09-20, Last modification date: 2025-05-28)

• Primary citation: Ognjenovic, J.,Merk, A.; Cryo-EM structure of the full-length human NF1 dimer; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)