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7YV8
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BU of 7yv8 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ...
Authors:Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
Deposit date:2022-08-18
Release date:2023-07-19
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
7YVU
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BU of 7yvu by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
Deposit date:2022-08-19
Release date:2023-07-19
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
6TCY
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BU of 6tcy by Molmil
X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with a inhibitor SS555
Descriptor: 1,2-ETHANEDIOL, 2-METHOXYETHANOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ...
Authors:Stransky, J, Barinka, C.
Deposit date:2019-11-06
Release date:2020-11-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
J.Med.Chem., 63, 2020
7BY7
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BU of 7by7 by Molmil
Bacteriophage SPO1 protein Gp46
Descriptor: Putative gene 46 protein
Authors:Liu, B, Zhang, P.
Deposit date:2020-04-22
Release date:2021-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins
Proc.Natl.Acad.Sci.USA, 119, 2022
6LJB
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BU of 6ljb by Molmil
Crystal Structure of ASFV pS273R protease
Descriptor: Cysteine protease S273R
Authors:Li, G.B, Liu, X.X, Chen, C, Guo, Y.
Deposit date:2019-12-13
Release date:2020-02-26
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.487 Å)
Cite:Crystal Structure of African Swine Fever Virus pS273R Protease and Implications for Inhibitor Design.
J.Virol., 94, 2020
8JUN
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BU of 8jun by Molmil
Cryo-EM structure of SIDT1 E555Q mutant
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION
Authors:Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
Deposit date:2023-06-26
Release date:2023-11-15
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
8JUL
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BU of 8jul by Molmil
Cryo-EM structure of SIDT1 in complex with phosphatidic acid
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, SID1 transmembrane family member 1, ZINC ION
Authors:Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
Deposit date:2023-06-26
Release date:2023-11-15
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
4ZIM
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BU of 4zim by Molmil
CRYSTAL STRUCTURE OF JANUS KINASE 2 IN COMPLEX WITH A 9H-CARBAZOLE-1-CARBOXAMIDE INHIBITOR
Descriptor: 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9H-carbazole-1-carboxamide, Tyrosine-protein kinase JAK2
Authors:Sack, J.S.
Deposit date:2015-04-28
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
6OYL
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BU of 6oyl by Molmil
The structure of the PP2A B56 subunit KIF4A complex
Descriptor: Chromosome-associated kinesin KIF4A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Wang, X, Page, R, Peti, W.
Deposit date:2019-05-14
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
8IK3
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BU of 8ik3 by Molmil
Structure of Stimulator of interferon genes/ligand complex
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
8IK0
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BU of 8ik0 by Molmil
Cryo-EM structure of Stimulator of interferon genes
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
7OU3
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BU of 7ou3 by Molmil
Crystal structure of Tga-AGOG, an 8-oxoguanine DNA glycosylase from Thermococcus gammatolerans
Descriptor: CHLORIDE ION, GLYCEROL, N-glycosylase/DNA lyase
Authors:Coste, F, Confalonieri, F, Castaing, B.
Deposit date:2021-06-11
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
7OUE
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BU of 7oue by Molmil
Crystal structure of a trapped Pab-AGOG/single-standed DNA covalent intermediate
Descriptor: DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), N-glycosylase/DNA lyase, PHOSPHATE ION, ...
Authors:Coste, F, Goffinont, S, Flament, D, Castaing, B.
Deposit date:2021-06-11
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
8U77
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BU of 8u77 by Molmil
Crystal structure of Taf14 in complex with Yng1
Descriptor: Protein YNG1, Transcription initiation factor TFIID subunit 14
Authors:Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G.
Deposit date:2023-09-14
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex.
Nat Commun, 15, 2024
7P8L
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BU of 7p8l by Molmil
Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(8OG)P*TP*TP*TP*CP*T)-3'), ...
Authors:Coste, F, Flament, D, Castaing, B.
Deposit date:2021-07-23
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
7P9Z
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BU of 7p9z by Molmil
Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing adenine opposite to lesion)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)*TP*TP*TP*CP*T)-3'), ...
Authors:Coste, F, Goffinont, S, Flament, D, Castaing, B.
Deposit date:2021-07-28
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022
5H5J
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BU of 5h5j by Molmil
Complex between ferredoxin and ferredoxin-NADP+ reductase from maize root
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, ...
Authors:Kurisu, G, Hase, T.
Deposit date:2016-11-05
Release date:2017-02-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the isotype-specific interactions of ferredoxin and ferredoxin: NADP(+) oxidoreductase: an evolutionary switch between photosynthetic and heterotrophic assimilation
Photosyn. Res., 134, 2017
7SGJ
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BU of 7sgj by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with DKFZ-711
Descriptor: 1,2-ETHANEDIOL, 4-[(3-anilino-3-oxopropyl)(methyl)amino]-N-hydroxybutanamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2021-10-05
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
J.Am.Chem.Soc., 144, 2022
7SGI
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BU of 7sgi by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Inhibitor 14
Descriptor: 5-[(2-anilino-2-oxoethyl)(methyl)amino]-N-hydroxypentanamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2021-10-05
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
J.Am.Chem.Soc., 144, 2022
8EN4
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BU of 8en4 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 53
Descriptor: 1,2-ETHANEDIOL, Nanobody 53, VP1
Authors:Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN5
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BU of 8en5 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 56
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GII.4 P domain, ...
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
7SGG
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BU of 7sgg by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with SAHA
Descriptor: DI(HYDROXYETHYL)ETHER, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2021-10-05
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
J.Am.Chem.Soc., 144, 2022
8EMZ
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BU of 8emz by Molmil
Structure of GII.17 norovirus in complex with Nanobody 2
Descriptor: 1,2-ETHANEDIOL, GII.17 P domain, Nanobody 2
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN0
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BU of 8en0 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 7
Descriptor: Capsid protein VP1, Nanobody 7
Authors:Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN1
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BU of 8en1 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 30
Descriptor: GII.4 P domain, Nanobody 30
Authors:Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
Deposit date:2022-09-28
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023

224004

數據於2024-08-21公開中

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