1IRX
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![BU of 1irx by Molmil](/molmil-images/mine/1irx) | Crystal structure of class I lysyl-tRNA synthetase | Descriptor: | ZINC ION, lysyl-tRNA synthetase | Authors: | Nureki, O, Terada, T, Ishitani, R, Ambrogelly, A, Ibba, M, Soll, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-10-25 | Release date: | 2002-04-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Functional convergence of two lysyl-tRNA synthetases with unrelated topologies. Nat.Struct.Biol., 9, 2002
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2ZIN
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![BU of 2zin by Molmil](/molmil-images/mine/2zin) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and an ATP analogue | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, ... | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-02-19 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification Chem.Biol., 15, 2008
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2ZCE
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![BU of 2zce by Molmil](/molmil-images/mine/2zce) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with pyrrolysine and an ATP analogue | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYRROLYSINE, ... | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-11-08 | Release date: | 2008-04-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase J.Mol.Biol., 378, 2008
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5ZSU
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![BU of 5zsu by Molmil](/molmil-images/mine/5zsu) | Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms | Descriptor: | Volume-regulated anion channel subunit LRRC8A | Authors: | Kasuya, G, Nakane, T, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | Deposit date: | 2018-04-29 | Release date: | 2018-08-15 | Last modified: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Cryo-EM structures of the human volume-regulated anion channel LRRC8. Nat. Struct. Mol. Biol., 25, 2018
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2CYX
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![BU of 2cyx by Molmil](/molmil-images/mine/2cyx) | Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) | Descriptor: | Ubiquitin-conjugating enzyme E2 G2 | Authors: | Yoshikawa, S, Arai, R, Murayama, K, Imai, Y, Takahashi, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-08 | Release date: | 2006-04-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) Acta Crystallogr.,Sect.F, 62, 2006
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2ZIO
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![BU of 2zio by Molmil](/molmil-images/mine/2zio) | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AlocLys-AMP and PNP | Descriptor: | 5'-O-[(S)-({(2S)-2-amino-6-[(propoxycarbonyl)amino]hexanoyl}oxy)(hydroxy)phosphoryl]adenosine, IMIDODIPHOSPHORIC ACID, Pyrrolysyl-tRNA synthetase | Authors: | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-02-19 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification Chem.Biol., 15, 2008
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2LHI
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![BU of 2lhi by Molmil](/molmil-images/mine/2lhi) | Solution structure of Ca2+/CNA1 peptide-bound yCaM | Descriptor: | CALCIUM ION, Calmodulin,Serine/threonine-protein phosphatase 2B catalytic subunit A1 | Authors: | Ogura, K, Takahashi, K, Kobashigawa, Y, Yoshida, R, Itoh, H, Yazawa, M, Inagaki, F. | Deposit date: | 2011-08-10 | Release date: | 2012-08-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin. Genes Cells, 17, 2012
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2LHH
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![BU of 2lhh by Molmil](/molmil-images/mine/2lhh) | Solution structure of Ca2+-bound yCaM | Descriptor: | CALCIUM ION, Calmodulin | Authors: | Ogura, K, Takahashi, K, Kobashigawa, Y, Yoshida, R, Itoh, H, Yazawa, M, Inagaki, F. | Deposit date: | 2011-08-10 | Release date: | 2012-08-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin. Genes Cells, 17, 2012
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2E21
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![BU of 2e21 by Molmil](/molmil-images/mine/2e21) | Crystal structure of TilS in a complex with AMPPNP from Aquifex aeolicus. | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, tRNA(Ile)-lysidine synthase | Authors: | Kuratani, M, Yoshikawa, Y, Sekine, S, Ishii, T, Shibata, R, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-11-06 | Release date: | 2007-11-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine To be Published
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2MX2
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![BU of 2mx2 by Molmil](/molmil-images/mine/2mx2) | UBX-L domain of VCIP135 | Descriptor: | Deubiquitinating protein VCIP135 | Authors: | Iwazu, T, Murayama, S, Igarashi, R, Hrioaki, H, Shirakawa, M, Tochio, H. | Deposit date: | 2014-12-07 | Release date: | 2016-07-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and interaction mode of the UBX-L domain of VCIP135 determined by solution NMR spectroscopy To be Published
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3AGK
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![BU of 3agk by Molmil](/molmil-images/mine/3agk) | Crystal structure of archaeal translation termination factor, aRF1 | Descriptor: | Peptide chain release factor subunit 1 | Authors: | Kobayashi, K, Kikuno, I, Ishitani, R, Ito, K, Nureki, O. | Deposit date: | 2010-04-01 | Release date: | 2010-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Omnipotent role of archaeal elongation factor 1 alpha (EF1{alpha}) in translational elongation and termination, and quality control of protein synthesis Proc.Natl.Acad.Sci.USA, 107, 2010
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3X3B
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![BU of 3x3b by Molmil](/molmil-images/mine/3x3b) | Crystal structure of the light-driven sodium pump KR2 in acidic state | Descriptor: | DI(HYDROXYETHYL)ETHER, OLEIC ACID, RETINAL, ... | Authors: | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | Deposit date: | 2015-01-18 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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3X3C
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![BU of 3x3c by Molmil](/molmil-images/mine/3x3c) | Crystal structure of the light-driven sodium pump KR2 in neutral state | Descriptor: | OLEIC ACID, RETINAL, Sodium pumping rhodopsin | Authors: | Kato, H.E, Inoue, K, Abe-Yoshizumi, R, Kato, Y, Ono, H, Konno, M, Ishizuka, T, Hoque, M.R, Hososhima, S, Kunitomo, H, Ito, J, Yoshizawa, S, Yamashita, K, Takemoto, M, Nishizawa, T, Taniguchi, R, Kogure, K, Maturana, A.D, Iino, Y, Yawo, H, Ishitani, R, Kandori, H, Nureki, O. | Deposit date: | 2015-01-18 | Release date: | 2015-04-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for Na(+) transport mechanism by a light-driven Na(+) pump Nature, 521, 2015
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1WWR
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![BU of 1wwr by Molmil](/molmil-images/mine/1wwr) | Crystal structure of tRNA adenosine deaminase TadA from Aquifex aeolicus | Descriptor: | ZINC ION, tRNA adenosine deaminase TadA | Authors: | Kuratani, M, Ishii, R, Bessho, Y, Fukunaga, R, Sengoku, T, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-12 | Release date: | 2005-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of tRNA Adenosine Deaminase (TadA) from Aquifex aeolicus J.Biol.Chem., 280, 2005
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2DBO
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![BU of 2dbo by Molmil](/molmil-images/mine/2dbo) | Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Aquifex aeolicus | Descriptor: | D-tyrosyl-tRNA(Tyr) deacylase | Authors: | Ishii, T, Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-15 | Release date: | 2006-06-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Aquifex aeolicus To be Published
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2DRD
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![BU of 2drd by Molmil](/molmil-images/mine/2drd) | Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, ACRB | Authors: | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | Deposit date: | 2006-06-08 | Release date: | 2006-08-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2DR6
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![BU of 2dr6 by Molmil](/molmil-images/mine/2dr6) | Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | Descriptor: | ACRB, DOXORUBICIN | Authors: | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | Deposit date: | 2006-06-08 | Release date: | 2006-08-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2DHH
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![BU of 2dhh by Molmil](/molmil-images/mine/2dhh) | |
1WPX
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![BU of 1wpx by Molmil](/molmil-images/mine/1wpx) | Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase Y, Carboxypeptidase Y inhibitor, ... | Authors: | Mima, J, Hayashida, M, Fujii, T, Narita, Y, Hayashi, R, Ueda, M, Hata, Y. | Deposit date: | 2004-09-14 | Release date: | 2005-03-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the carboxypeptidase y inhibitor i(c) in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction J.Mol.Biol., 346, 2005
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1WJX
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![BU of 1wjx by Molmil](/molmil-images/mine/1wjx) | Crystal sturucture of TT0801 from Thermus thermophilus | Descriptor: | POTASSIUM ION, SsrA-binding protein | Authors: | Bessho, Y, Shibata, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-29 | Release date: | 2004-11-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA. Proc.Natl.Acad.Sci.Usa, 104, 2007
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5YIL
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![BU of 5yil by Molmil](/molmil-images/mine/5yil) | Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains | Descriptor: | Multidrug efflux pump subunit AcrB | Authors: | Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. | Deposit date: | 2017-10-05 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains. Front Microbiol, 8, 2017
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2CZJ
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![BU of 2czj by Molmil](/molmil-images/mine/2czj) | Crystal structure of the tRNA domain of tmRNA from Thermus thermophilus HB8 | Descriptor: | SsrA-binding protein, tmRNA (63-MER) | Authors: | Bessho, Y, Shibata, R, Sekine, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-13 | Release date: | 2006-10-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E88
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![BU of 2e88 by Molmil](/molmil-images/mine/2e88) | Crystal structure of the human Hsp70 ATPase domain in the apo form | Descriptor: | Heat shock 70kDa protein 1A, ZINC ION | Authors: | Shida, M, Ishii, R, Takagi, T, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-19 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66, 2010
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5XUZ
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![BU of 5xuz by Molmil](/molmil-images/mine/5xuz) | Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (CCCA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*CP*CP*CP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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5XUT
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![BU of 5xut by Molmil](/molmil-images/mine/5xut) | Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCTA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*CP*TP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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