4ZSE
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6DDM
| Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody | Descriptor: | Anti-MICA Fab fragment heavy chain clone 1D5, Anti-MICA Fab fragment light chain clone 1D5, MHC class I polypeptide-related sequence A | Authors: | Matsumoto, M.L. | Deposit date: | 2018-05-10 | Release date: | 2018-10-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11, 2019
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6DDV
| Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody | Descriptor: | Anti-MICA Fab fragment heavy chain clone 6E1, Anti-MICA Fab fragment light chain clone 6E1, MHC class I chain-related protein A | Authors: | Matsumoto, M.L. | Deposit date: | 2018-05-10 | Release date: | 2018-10-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11, 2019
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5GRD
| Crystal structure of 10-mer peptide from EBV in complex with HLA-A1101. | Descriptor: | Beta-2-microglobulin, Epstein Barr Virus, Latent membrane protein 2 epitope, ... | Authors: | Tadwal, V.S, Xiao, Z, Ren, E.C. | Deposit date: | 2016-08-10 | Release date: | 2017-08-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens Sci Rep, 7, 2017
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5GSD
| Crystal structure of LMP2 peptide from EBV in complex with HLA-A*11:01 | Descriptor: | Beta-2-microglobulin, Epstein Barr Virus, Latent membrane protein-2 epitope, ... | Authors: | Tadwal, V.S, Xiao, Z, Ren, E.C. | Deposit date: | 2016-08-15 | Release date: | 2017-08-09 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens Sci Rep, 7, 2017
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5GRG
| Crystal structure of dual peptide from EBV in complex with HLA-A*11:01 | Descriptor: | Beta-2-microglobulin, Epstein Barr Virus, Latent Membrane Protein 2 epitope, ... | Authors: | Tadwal, V.S, Xiao, Z, Ren, E.C. | Deposit date: | 2016-08-11 | Release date: | 2017-08-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens Sci Rep, 7, 2017
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6TGW
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3QOE
| Crystal Structure of Heterocyst Differentiation Protein, HetR from Fischerella mv11 | Descriptor: | Heterocyst differentiation protein | Authors: | Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-09 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria. Proc.Natl.Acad.Sci.USA, 108, 2011
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5YU9
| Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib | Descriptor: | 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, CHLORIDE ION, Epidermal growth factor receptor | Authors: | Yan, X.E, Yun, C.H. | Deposit date: | 2017-11-21 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation. Oncotarget, 7, 2016
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3QOD
| Crystal Structure of Heterocyst Differentiation Protein, HetR from Fischerella mv11 | Descriptor: | Heterocyst differentiation protein | Authors: | Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-09 | Release date: | 2011-04-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria. Proc.Natl.Acad.Sci.USA, 108, 2011
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1XHN
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4J01
| Crystal Structure of Fischerella Transcription Factor HetR complexed with 29mer DNA target | Descriptor: | DNA (29-MER), SULFATE ION, Transcription Factor HetR | Authors: | Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-01-30 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.246 Å) | Cite: | Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IZZ
| Crystal Structure of Fischerella Transcription Factor HetR complexed with 21mer DNA target | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*TP*GP*AP*GP*GP*GP*GP*TP*TP*AP*AP*AP*CP*CP*CP*CP*TP*CP*AP*C)-3'), SULFATE ION, ... | Authors: | Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-01-30 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets. Proc.Natl.Acad.Sci.USA, 110, 2013
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4J00
| Crystal Structure of Fischerella Transcription Factor HetR complexed with 24mer DNA target | Descriptor: | DNA (5'-D(*TP*GP*GP*TP*GP*AP*GP*GP*GP*GP*TP*TP*AP*AP*AP*CP*CP*CP*CP*TP*CP*AP*CP*C)-3'), MAGNESIUM ION, Transcription Factor HetR | Authors: | Kim, Y, Joachimiak, G, Gornicki, P, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-01-30 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets. Proc.Natl.Acad.Sci.USA, 110, 2013
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8K60
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1O77
| CRYSTAL STRUCTURE OF THE C713S MUTANT OF THE TIR DOMAIN OF HUMAN TLR2 | Descriptor: | TOLL-LIKE RECEPTOR 2 | Authors: | Tao, X, Xu, Y, Ye, Z, Beg, A.A, Tong, L. | Deposit date: | 2002-10-24 | Release date: | 2002-11-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | An Extensively Associated Dimer in the Structure of the C713S Mutant of the Tir Domain of Human Tlr2 Biochem.Biophys.Res.Commun., 299, 2002
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8IP0
| Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution | Descriptor: | CRISPR associated protein Cas11b, DNA (41-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | Deposit date: | 2023-03-13 | Release date: | 2024-03-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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8U32
| Crystal structure of PD-1 in complex with a Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Sun, D, Masureel, M. | Deposit date: | 2023-09-07 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability. Mabs, 16, 2024
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8U31
| Crystal structure of PD-1 in complex with a Fab | Descriptor: | Fab heavy chain, Fab light chain, GLYCEROL, ... | Authors: | Sun, D, Masureel, M. | Deposit date: | 2023-09-07 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability. Mabs, 16, 2024
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8GXF
| Pseudomonas flexibilis GCN5 family acetyltransferase | Descriptor: | COENZYME A, GCN5 family acetyltransferase | Authors: | Song, Y.J, Bao, R. | Deposit date: | 2022-09-20 | Release date: | 2022-10-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022
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8GXJ
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8GXK
| Pseudomonas jinjuensis N-acetyltransferase | Descriptor: | COENZYME A, Protein N-acetyltransferase, RimJ/RimL family | Authors: | Song, Y.J, Bao, R. | Deposit date: | 2022-09-20 | Release date: | 2022-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022
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6N6B
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