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8D6W
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BU of 8d6w by Molmil
Structure of the Mycobacterium tuberculosis 20S proteasome bound to the C-terminal GQYL motif of the ADP-bound Mpa ATPase
Descriptor: Proteasome subunit alpha, Proteasome subunit beta, Proteasome-associated ATPase
Authors:Xiao, X, Li, H.
Deposit date:2022-06-06
Release date:2022-08-03
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation.
Msphere, 7, 2022
8D6V
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BU of 8d6v by Molmil
Structure of the Mycobacterium tuberculosis 20S proteasome bound to the C-terminal GQYL motif of the ATP-bound Mpa ATPase
Descriptor: Proteasome subunit alpha, Proteasome subunit beta, Proteasome-associated ATPase
Authors:Xiao, X, Li, H.
Deposit date:2022-06-06
Release date:2022-08-03
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation.
Msphere, 7, 2022
8D6X
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BU of 8d6x by Molmil
Structure of the Mycobacterium tuberculosis 20S proteasome bound to the ATP-bound Mpa ATPase
Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta, ...
Authors:Xiao, X, Li, H.
Deposit date:2022-06-06
Release date:2022-08-03
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation.
Msphere, 7, 2022
5K83
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BU of 5k83 by Molmil
Crystal Structure of a Primate APOBEC3G N-Domain, in Complex with ssDNA
Descriptor: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G,Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ...
Authors:Xiao, X, Li, S.-X, Yang, H, Chen, X.S.
Deposit date:2016-05-27
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Nat Commun, 7, 2016
5K81
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BU of 5k81 by Molmil
Crystal Structure of a Primate APOBEC3G N-Terminal Domain
Descriptor: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G,Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ...
Authors:Xiao, X, Li, S.-X, Yang, H, Chen, X.S.
Deposit date:2016-05-27
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Nat Commun, 7, 2016
5K82
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BU of 5k82 by Molmil
Crystal Structure of a Primate APOBEC3G N-Terminal Domain
Descriptor: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G,Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ...
Authors:Xiao, X, Li, S.-X, Yang, H, Chen, X.S.
Deposit date:2016-05-27
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Nat Commun, 7, 2016
8GB3
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BU of 8gb3 by Molmil
Structure of the Mycobacterium tuberculosis Hsp70 protein DnaK bound to the nucleotide exchange factor GrpE
Descriptor: Chaperone protein DnaK, Protein GrpE
Authors:Xiao, X, Li, H.
Deposit date:2023-02-24
Release date:2024-01-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the M. tuberculosis DnaK-GrpE complex reveals how key DnaK roles are controlled.
Nat Commun, 15, 2024
5HZR
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BU of 5hzr by Molmil
Crystal structure of MtSnf2
Descriptor: 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, SNF2-family ATP dependent chromatin remodeling factor like protein, SODIUM ION, ...
Authors:Chen, Z.C, Xia, X.
Deposit date:2016-02-02
Release date:2016-07-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure of chromatin remodeler Swi2/Snf2 in the resting state
Nat.Struct.Mol.Biol., 23, 2016
4QAL
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BU of 4qal by Molmil
Crystal structure of C117A mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4Q9G
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BU of 4q9g by Molmil
Crystal structure of K12V/C16S/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-01
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.554 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBC
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BU of 4qbc by Molmil
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer
Descriptor: FORMIC ACID, Fibroblast growth factor 1, SULFATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-07
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.519 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBV
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BU of 4qbv by Molmil
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QC4
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BU of 4qc4 by Molmil
Crystal structure of C117S mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE, ...
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-09
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4Q9P
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BU of 4q9p by Molmil
Crystal structure of C16T/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-01
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
7AZN
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BU of 7azn by Molmil
Structure of mouse AsterC (GramD1c) with a new cholesterol-derived compound
Descriptor: 20alpha-hydroxy-20-(5-methylhexyl)cholesterol, ETHANOL, GLYCEROL, ...
Authors:Romartinez-Alonso, B, Sirvydis, K, Kim, Y, Xiao, X, Jung, M, Tontonoz, P, Schwabe, J.
Deposit date:2020-11-16
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms.
Proc.Natl.Acad.Sci.USA, 118, 2021
2XUT
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BU of 2xut by Molmil
Crystal structure of a proton dependent oligopeptide (POT) family transporter.
Descriptor: PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
Authors:Newstead, S, Drew, D, Cameron, A.D, Postis, V.L, Xia, X, Fowler, P.W, Ingram, J.C, Carpenter, E.P, Sansom, M.S.P, McPherson, M.J, Baldwin, S.A, Iwata, S.
Deposit date:2010-10-21
Release date:2010-12-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
7L8K
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BU of 7l8k by Molmil
Crystal structure of human GPX4-U46C
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ...
Authors:Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R.
Deposit date:2020-12-31
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism
Nat.Chem.Biol., 2021
7L8Q
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BU of 7l8q by Molmil
Crystal structure of human GPX4-U46C with oxidized Cys-46
Descriptor: ACETATE ION, Phospholipid hydroperoxide glutathione peroxidase
Authors:Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R.
Deposit date:2020-12-31
Release date:2021-12-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism
Nat.Chem.Biol., 2021
7L8R
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BU of 7l8r by Molmil
Crystal structure of human GPX4-U46C mutant K48A
Descriptor: Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION
Authors:Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R.
Deposit date:2020-12-31
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism
Nat.Chem.Biol., 2021
7L8L
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BU of 7l8l by Molmil
Crystal structure of human R152H GPX4-U46C
Descriptor: Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION
Authors:Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R.
Deposit date:2020-12-31
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism
Nat.Chem.Biol., 2021
7L8M
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BU of 7l8m by Molmil
Crystal structure of human GPX4-U46C mutant K48L
Descriptor: Phospholipid hydroperoxide glutathione peroxidase
Authors:Forouhar, F, Liu, H, Seibt, T, Saneto, R, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R.
Deposit date:2020-12-31
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism
Nat.Chem.Biol., 2021
5X0X
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BU of 5x0x by Molmil
Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome
Descriptor: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Li, M, Liu, X, Xia, X, Chen, Z, Li, X.
Deposit date:2017-01-23
Release date:2017-04-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
5X0Y
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BU of 5x0y by Molmil
Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome
Descriptor: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Li, M, Liu, X, Xia, X, Chen, Z, Li, X.
Deposit date:2017-01-23
Release date:2017-04-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
8FJP
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BU of 8fjp by Molmil
Cryo-EM structure of native mosquito salivary gland surface protein 1 (SGS1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, salivary gland surface protein 1
Authors:Liu, S, Xia, X, Calvo, E, Zhou, Z.H.
Deposit date:2022-12-20
Release date:2023-03-01
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Native structure of mosquito salivary protein uncovers domains relevant to pathogen transmission.
Nat Commun, 14, 2023
5C65
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BU of 5c65 by Molmil
Structure of the human glucose transporter GLUT3 / SLC2A3
Descriptor: CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ...
Authors:Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2015-06-22
Release date:2015-07-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the human glucose transporter GLUT3 / SLC2A3
To Be Published

227111

數據於2024-11-06公開中

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