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7Z62
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BU of 7z62 by Molmil
Structure of the LecA lectin from Pseudomonas aeruginosa in complex with a biaryl-thiogalactoside
Descriptor: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[4-[1-(4-methoxyphenyl)ethenyl]phenyl]sulfanyl-oxane-3,4,5-triol, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Varrot, A.
Deposit date:2022-03-10
Release date:2023-01-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties.
Eur.J.Med.Chem., 247, 2022
6HTN
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BU of 6htn by Molmil
Structure of a fucose lectin from Kordia zhangzhouensis in complex with methyl-fucoside
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
Authors:Varrot, A.
Deposit date:2018-10-04
Release date:2019-01-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Architecture and Evolution of Blade Assembly in beta-propeller Lectins.
Structure, 27, 2019
5M1Z
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BU of 5m1z by Molmil
STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR
Descriptor: 1,2-ETHANEDIOL, Exo-1,5-alpha-L-arabinofuranobiosidase, GLYCEROL, ...
Authors:Varrot, A.
Deposit date:2016-10-11
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploiting sp(2) -Hybridisation in the Development of Potent 1,5-alpha-l-Arabinanase Inhibitors.
Chembiochem, 18, 2017
8BRO
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BU of 8bro by Molmil
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-fucosylamide
Descriptor: 5-[3-(aminomethyl)phenyl]-~{N}-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]furan-2-carboxamide, Lectin
Authors:Varrot, A, Lunstrom, J.
Deposit date:2022-11-23
Release date:2023-02-08
Last modified:2023-02-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from Burkholderia cenocepacia.
Molecules, 28, 2023
8R8C
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BU of 8r8c by Molmil
Structure of the N-terminal domain of CMA from Cucumis melo in complex with N-acetylgalactosamine
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CADMIUM ION, ...
Authors:Varrot, A.
Deposit date:2023-11-28
Release date:2023-12-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Elucidating the glycan-binding specificity and structure of Cucumis melo agglutinin, a new R-type lectin.
Beilstein J Org Chem, 20, 2024
6TIG
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BU of 6tig by Molmil
Structure of the N terminal domain of Bc2L-C lectin (1-131) in complex with Globo H (H-type 3) antigen
Descriptor: Lectin, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose
Authors:Varrot, A, Bermeo, R.
Deposit date:2019-11-22
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:BC2L-C N-Terminal Lectin Domain Complexed with Histo Blood Group Oligosaccharides Provides New Structural Information.
Molecules, 25, 2020
6TID
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BU of 6tid by Molmil
Structure of the N terminal domain of Bc2L-C lectin (1-131) in complex with H-type 1 antigen
Descriptor: Lectin, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Varrot, A, Bermeo, R.
Deposit date:2019-11-22
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.614 Å)
Cite:BC2L-C N-Terminal Lectin Domain Complexed with Histo Blood Group Oligosaccharides Provides New Structural Information.
Molecules, 25, 2020
7PRP
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BU of 7prp by Molmil
Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in apo form
Descriptor: FORMIC ACID, Heat-labile enterotoxin IIA, B chain, ...
Authors:Varrot, A.
Deposit date:2021-09-22
Release date:2021-12-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.
Glycobiology, 32, 2022
7PRS
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BU of 7prs by Molmil
Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in complex with Sialyl-lacto-N-neotetraose d
Descriptor: Heat-labile enterotoxin IIA, B chain, N-acetyl-alpha-neuraminic acid, ...
Authors:Varrot, A.
Deposit date:2021-09-22
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.
Glycobiology, 32, 2022
6Z6C
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BU of 6z6c by Molmil
Crystal structurel of FleA lectin in complex with a monovalent inhibitor
Descriptor: 4-((1-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl-a-L-thiofucoside, Fucose-specific lectin, GLYCEROL, ...
Authors:Varrot, A.
Deposit date:2020-05-28
Release date:2021-04-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Hexavalent thiofucosides to probe the role of the Aspergillus fumigatus lectin FleA in fungal pathogenicity.
Org.Biomol.Chem., 19, 2021
5O7V
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BU of 5o7v by Molmil
Crystal structure of the 5F-tryptophan RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: CHLORIDE ION, ETHANOL, Fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
5O7U
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BU of 5o7u by Molmil
Crystal structure of the 7-Fluorotryptophan RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: CALCIUM ION, MAGNESIUM ION, Putative fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
5O7W
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BU of 5o7w by Molmil
Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Putative fucose-binding lectin protein, ...
Authors:Varrot, A.
Deposit date:2017-06-09
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.
ACS Chem. Biol., 13, 2018
6ZU2
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BU of 6zu2 by Molmil
CML1 crystal structure in complex with H-type 1 trisaccharide
Descriptor: Mucin-binding lectin 1, SULFATE ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Varrot, A, Bleuler-Martinez, S.
Deposit date:2020-07-21
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity.
Glycobiology, 32, 2022
6ZV5
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BU of 6zv5 by Molmil
CML1 crystal structure in complex with Lewis a tetrasaccharide
Descriptor: Mucin-binding lectin 1, SULFATE ION, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Varrot, A, Bleuler-Martinez, S.
Deposit date:2020-07-24
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity.
Glycobiology, 32, 2022
2W4S
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BU of 2w4s by Molmil
novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution
Descriptor: Ankyrin-repeat protein
Authors:Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S.
Deposit date:2008-12-02
Release date:2009-12-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
1UP6
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BU of 1up6 by Molmil
Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.55 Angstrom resolution in the tetragonal form with manganese, NAD+ and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, MANGANESE (II) ION, ...
Authors:Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J.
Deposit date:2003-09-29
Release date:2004-08-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 Beta-Glycosidase from Thermotoga Maritima.
J.Am.Chem.Soc., 126, 2004
4UT5
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BU of 4ut5 by Molmil
Crystal structure of the LecB lectin from Pseudomonas aeruginosa strain PA7 in complex with lewis a tetrasaccharide
Descriptor: CALCIUM ION, LECB LECTIN, beta-D-galactopyranose, ...
Authors:Boukerb, A.M, Decor, A, Tabaroni, R, Varrot, A, Debentzmann, S, Vidal, S, Imberty, A, Cournoyer, B.
Deposit date:2014-07-18
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Genomic Rearrangements and Functional Diversification of Leca and Lecb Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed Against Pseudomonas Aeruginosa.
Front.Microbiol., 7, 2016
6R35
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BU of 6r35 by Molmil
Structure of the LecB lectin from Pseudomonas aeruginosa strain PAO1 in complex with lewis x tetrasaccharide
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Fucose-binding lectin PA-IIL, ...
Authors:Lepsik, M, Sommer, R, Kuhaudomlarp, S, Lelimousin, M, Varrot, A, Titz, A, Imberty, A.
Deposit date:2019-03-19
Release date:2019-06-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study.
Eur.J.Med.Chem., 177, 2019
5FRA
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BU of 5fra by Molmil
CBM40_CPF0721-6'SL
Descriptor: ACETATE ION, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ...
Authors:Ribeiro, J.P, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A.
Deposit date:2015-12-16
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form.
Biochem.J., 473, 2016
5FSB
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BU of 5fsb by Molmil
Structure of tectonin 2 from laccaria bicolor in complex with 2-o-methyl-methyl-seleno-beta-l-fucopyranoside
Descriptor: BORIC ACID, MAGNESIUM ION, SULFATE ION, ...
Authors:Sommer, R, Bleuer, S, Titz, A, Kunzler, M, Varrot, A.
Deposit date:2016-01-04
Release date:2017-03-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense.
Structure, 26, 2018
5FRE
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BU of 5fre by Molmil
Characterization of a novel CBM from Clostridium perfringens
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, CALCIUM ION, ...
Authors:Ribeiro, J, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A.
Deposit date:2015-12-17
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form.
Biochem.J., 473, 2016
8GUV
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BU of 8guv by Molmil
LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7)
Descriptor: CALCIUM ION, PA-I galactophilic lectin, Tolcapone
Authors:Kuhaudomlarp, S, Siebs, E, Varrot, A, Imberty, A, Titz, A.
Deposit date:2022-09-13
Release date:2023-07-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7)
To Be Published
4I6S
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BU of 4i6s by Molmil
Structure of RSL mutant W76A in complex with L-fucose
Descriptor: 1,2-ETHANEDIOL, Putative fucose-binding lectin protein, TETRAETHYLENE GLYCOL, ...
Authors:Audfray, A, Arnaud, J, Varrot, A, Imberty, A.
Deposit date:2012-11-30
Release date:2013-07-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Reduction of lectin valency drastically changes glycolipid dynamics in membranes but not surface avidity
Acs Chem.Biol., 8, 2013
4UP4
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BU of 4up4 by Molmil
Structure of the recombinant lectin PVL from Psathyrella velutina in complex with GlcNAcb-D-1,3Galactoside
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
Authors:Audfray, A, Beljoudi, M, Hurbin, A, Varrot, A, Breiman, A, Busser, B, Lependu, J, Coll, J.L, Imberty, A.
Deposit date:2014-06-12
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Recombinant Fungal Lectin for Labeling Truncated Glycans on Human Cancer Cells.
Plos One, 10, 2015

221051

數據於2024-06-12公開中

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