6QCX
 
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6QCV
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6QCS
 | | Influenza B polymerase pre-initiation complex | | Descriptor: | 3 end, 5 end, Capped RNA, ... | | Authors: | Cusack, S, Kouba, T. | | Deposit date: | 2018-12-30 | | Release date: | 2019-06-05 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019
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6QCW
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6QCT
 | | Influenza B polymerase elongation complex | | Descriptor: | 3 end, 5 end, MAGNESIUM ION, ... | | Authors: | Cusack, S, Kouba, T. | | Deposit date: | 2018-12-30 | | Release date: | 2019-06-05 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019
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6FSB
 | | Influenza B/Memphis/13/03 endonuclease with I38T mutation | | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, Polymerase acidic protein | | Authors: | Cusack, S, Speranzini, V. | | Deposit date: | 2018-02-19 | | Release date: | 2018-07-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
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6FS8
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6FS6
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6FS9
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6FS7
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2BTE
 | | Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue | | Descriptor: | 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ... | | Authors: | Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. | | Deposit date: | 2005-05-31 | | Release date: | 2005-09-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
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2BYT
 | | Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation | | Descriptor: | LEUCINE, LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, ... | | Authors: | Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. | | Deposit date: | 2005-08-04 | | Release date: | 2005-09-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer-Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
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7QTL
 | | Influenza A/H7N9 polymerase elongation complex | | Descriptor: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ... | | Authors: | Cusack, S, Kouba, T. | | Deposit date: | 2022-01-14 | | Release date: | 2022-12-28 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.48 Å) | | Cite: | Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
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7R0E
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7R1F
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5MSG
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6TU5
 | | Influenza A/H7N9 polymerase core (apo) | | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Cusack, S, Pflug, A. | | Deposit date: | 2020-01-02 | | Release date: | 2020-04-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.325 Å) | | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
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6F7S
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6F7P
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6FLN
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6F8D
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6FLM
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7ZPM
 | | Influenza A/H7N9 polymerase apo-protein dimer complex | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | | Authors: | Cusack, S, Kouba, T. | | Deposit date: | 2022-04-27 | | Release date: | 2022-12-28 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
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7ZPL
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9F3V
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