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Solution structure of BCL-xL containing the alpha1-alpha2 disordered loop determined with selective isotope labelling of I,L,V sidechains
Descriptor:	Bcl-2-like protein 1
Authors:	Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:	2013-09-25
Release date:	2014-04-30
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014

6CDE

Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
Authors:	Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D.
Deposit date:	2018-02-08
Release date:	2018-05-16
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

6CDO

Structure of vaccine-elicited HIV-1 neutralizing antibody vFP16.02 in complex with HIV-1 fusion peptide residue 512-519
Descriptor:	HIV-1 fusion peptide 512-519, SULFATE ION, vFP16.02 Fab heavy chain, ...
Authors:	Xu, K, Liu, K, Kwong, P.D.
Deposit date:	2018-02-08
Release date:	2018-05-16
Last modified:	2018-06-20
Method:	X-RAY DIFFRACTION (2.099 Å)
Cite:	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

6CDP

Vaccine-elicited HIV-1 neutralizing antibody vFP20.01 in complex with HIV-1 fusion peptide residue 512-519
Descriptor:	HIV-1 fusion peptide 512-519, SULFATE ION, vFP20.01 Fab heavy chain, ...
Authors:	Xu, K, Liu, K, Kwong, P.D.
Deposit date:	2018-02-08
Release date:	2018-05-16
Last modified:	2018-06-20
Method:	X-RAY DIFFRACTION (2.456 Å)
Cite:	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

6CDI

Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
Authors:	Acharya, P, Xu, K, Liu, K, Carragher, B, Potter, C.S, Kwong, P.D.
Deposit date:	2018-02-08
Release date:	2018-05-16
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

6CDM

Structure of vaccine-elicited HIV-1 neutralizing antibody vFP7.04 in complex with HIV-1 fusion peptide residue 512-519
Descriptor:	HIV fusion peptide (512-519), vFP7.04 heavy chain, vFP7.04 light chain
Authors:	Xu, K, Liu, K, Kwong, P.D.
Deposit date:	2018-02-08
Release date:	2018-05-16
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.408 Å)
Cite:	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nat. Med., 24, 2018

7RDA

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138
Descriptor:	Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD9

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159
Descriptor:	Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.91 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD3

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126
Descriptor:	Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.81 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RAJ

Structure of PfCSP peptide 21 with antibody iGL-CIS43.D3
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN-ALA-ASN, ZINC ION, ...
Authors:	Tripathi, P, Kwong, P.D.
Deposit date:	2021-07-01
Release date:	2021-12-15
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RCS

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160
Descriptor:	Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-08
Release date:	2021-12-15
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD4

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149
Descriptor:	Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

6MQC

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
Descriptor:	0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-09
Release date:	2019-07-31
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.99 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MPH

Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ...
Authors:	Acharya, P, Xu, K, Kwong, P.D.
Deposit date:	2018-10-06
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6N16

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV fusion peptide (512-519), antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-11-08
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.302 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MPG

Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-10-06
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQE

Vaccine-elicited NHP FP-targeting HIV neutralizing antibody DFPH-a.15 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	DFPHa.15 antibody Fab heavy chain, DFPHa.15 antibody Fab light chain, HIV fusion peptide
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-09
Release date:	2019-07-31
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.459 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQS

Vaccine-elicited NHP FP-targeting HIV neutralizing antibody A12V163-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV fusion peptide residue 512-519, antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.997 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6N1W

Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DFPH-a.15 Light chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-11-12
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6N1V

Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-a.01 Heavy chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-11-12
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (4 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQR

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519)
Descriptor:	CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ...
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQM

Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV Env fusion peptide residue 512-519, antibody Fab heavy chain, antibody Fab light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (3.484 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6W03

Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:	Lai, Y.-T, Kwong, P.D.
Deposit date:	2020-02-28
Release date:	2020-04-15
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses. J.Virol., 94, 2020

2MEJ

Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Descriptor:	Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION
Authors:	Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:	2013-09-25
Release date:	2014-04-30
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014

2ME8

Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
Descriptor:	Bcl-2-like protein 1
Authors:	Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:	2013-09-25
Release date:	2014-04-30
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014

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Displayed results:	25
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