7MJS
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![BU of 7mjs by Molmil](/molmil-images/mine/7mjs) | Single-Particle Cryo-EM Structure of Major Facilitator Superfamily Domain containing 2A in complex with LPC-18:3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2AG3 Fab heavy chain, 2AG3 Fab light chain, ... | Authors: | Cater, R.J, Chua, G.L, Erramilli, S.K, Keener, J.E, Choy, B.C, Tokarz, P, Chin, C.F, Quek, D.Q.Y, Kloss, B, Pepe, J.G, Parisi, G, Wong, B.H, Clarke, O.B, Marty, M.T, Kossiakoff, A.A, Khelashvili, G, Silver, D.L, Mancia, F. | Deposit date: | 2021-04-20 | Release date: | 2021-06-16 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature, 595, 2021
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3TX3
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![BU of 3tx3 by Molmil](/molmil-images/mine/3tx3) | CysZ, a putative sulfate permease | Descriptor: | CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, SULFATE ION, ... | Authors: | Assur, Z, Liu, Q, Hendrickson, W.A, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2011-09-22 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CysZ, a putative sulfate permease To be Published
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4Q7C
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![BU of 4q7c by Molmil](/molmil-images/mine/4q7c) | Structure of AF2299, a CDP-alcohol phosphotransferase | Descriptor: | AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ... | Authors: | Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-04-24 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun, 5, 2014
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6UKJ
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![BU of 6ukj by Molmil](/molmil-images/mine/6ukj) | Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform | Descriptor: | CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ... | Authors: | Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F. | Deposit date: | 2019-10-05 | Release date: | 2019-12-04 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Nature, 576, 2019
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6WBX
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![BU of 6wbx by Molmil](/molmil-images/mine/6wbx) | Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 1 | Descriptor: | CALCIUM ION, DUF3367 domain-containing protein | Authors: | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | Deposit date: | 2020-03-27 | Release date: | 2020-05-13 | Last modified: | 2020-06-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
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6WBY
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![BU of 6wby by Molmil](/molmil-images/mine/6wby) | Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria, Mutant R1389S Class 2 | Descriptor: | CALCIUM ION, DUF3367 domain-containing protein | Authors: | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | Deposit date: | 2020-03-27 | Release date: | 2020-05-13 | Last modified: | 2020-06-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
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6X0O
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![BU of 6x0o by Molmil](/molmil-images/mine/6x0o) | Single-Particle Cryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbB | Authors: | Tan, Y.Z, Rodrigues, J, Keener, J.E, Zheng, R.B, Brunton, R, Kloss, B, Giacometti, S.I, Rosario, A.L, Zhang, L, Niederweis, M, Clarke, O.B, Lowary, T.L, Marty, M.T, Archer, M, Potter, C.S, Carragher, B, Mancia, F. | Deposit date: | 2020-05-17 | Release date: | 2020-06-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis. Nat Commun, 11, 2020
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6W98
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![BU of 6w98 by Molmil](/molmil-images/mine/6w98) | Single-Particle Cryo-EM Structure of Arabinofuranosyltransferase AftD from Mycobacteria | Descriptor: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, CALCIUM ION, ... | Authors: | Tan, Y.Z, Zhang, L, Rodrigues, J, Zheng, R.B, Giacometti, S.I, Rosario, A.L, Kloss, B, Dandey, V.P, Wei, H, Brunton, R, Raczkowski, A.M, Athayde, D, Catalao, M.J, Pimentel, M, Clarke, O.B, Lowary, T.L, Archer, M, Niederweis, M, Potter, C.S, Carragher, B, Mancia, F. | Deposit date: | 2020-03-22 | Release date: | 2020-05-13 | Last modified: | 2020-06-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria. Mol.Cell, 78, 2020
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6WMV
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![BU of 6wmv by Molmil](/molmil-images/mine/6wmv) | Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii with evidence of substrate binding | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,3',3''-phosphanetriyltripropanoic acid, AfCTD-Phosphatidylinositol-phosphate synthase (PIPS) fusion, ... | Authors: | Belcher Dufrisne, M, Jorge, C.D, Timoteo, C.G, Petrou, V.I, Ashraf, K.U, Banerjee, S, Clarke, O.B, Santos, H, Mancia, F. | Deposit date: | 2020-04-21 | Release date: | 2020-05-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.142 Å) | Cite: | Structural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria. J.Mol.Biol., 432, 2020
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5D91
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![BU of 5d91 by Molmil](/molmil-images/mine/5d91) | Structure of a phosphatidylinositolphosphate (PIP) synthase from Renibacterium Salmoninarum | Descriptor: | AF2299 protein,Phosphatidylinositol synthase, MAGNESIUM ION, Octadecane, ... | Authors: | Clarke, O.B, Tomasek, D.T, Jorge, C.D, Belcher Dufrisne, M, Kim, M, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Santos, H, Mancia, F. | Deposit date: | 2015-08-18 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural basis for phosphatidylinositol-phosphate biosynthesis. Nat Commun, 6, 2015
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5F15
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![BU of 5f15 by Molmil](/molmil-images/mine/5f15) | Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase, CHLORIDE ION, ... | Authors: | Petrou, V.I, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2015-11-30 | Release date: | 2016-02-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation. Science, 351, 2016
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5EZM
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![BU of 5ezm by Molmil](/molmil-images/mine/5ezm) | Crystal Structure of ArnT from Cupriavidus metallidurans in the apo state | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferases of PMT family, CHLORIDE ION, ... | Authors: | Petrou, V.I, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2015-11-26 | Release date: | 2016-02-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation. Science, 351, 2016
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5EKE
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![BU of 5eke by Molmil](/molmil-images/mine/5eke) | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (F215A mutant) | Descriptor: | MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 | Authors: | Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2015-11-03 | Release date: | 2016-01-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
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5EKP
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![BU of 5ekp by Molmil](/molmil-images/mine/5ekp) | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (WT) | Descriptor: | MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 | Authors: | Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2015-11-03 | Release date: | 2016-01-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.194 Å) | Cite: | Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
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5D92
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![BU of 5d92 by Molmil](/molmil-images/mine/5d92) | Structure of a phosphatidylinositolphosphate (PIP) synthase from Renibacterium Salmoninarum | Descriptor: | 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, AF2299 protein,Phosphatidylinositol synthase, MAGNESIUM ION, ... | Authors: | Clarke, O.B, Tomasek, D.T, Jorge, C.D, Belcher Dufrisne, M, Kim, M, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Santos, H, Mancia, F. | Deposit date: | 2015-08-18 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Structural basis for phosphatidylinositol-phosphate biosynthesis. Nat Commun, 6, 2015
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8PM2
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![BU of 8pm2 by Molmil](/molmil-images/mine/8pm2) | Structure of the murine trace amine-associated receptor TAAR7f bound to N,N-dimethylcyclohexylamine (DMCH) in complex with mini-Gs trimeric G protein | Descriptor: | CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Gusach, A, Lee, Y, Edwards, P.C, Huang, F, Weyand, S.N, Tate, C.G. | Deposit date: | 2023-06-28 | Release date: | 2023-08-09 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f. Biorxiv, 2023
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1NMT
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![BU of 1nmt by Molmil](/molmil-images/mine/1nmt) | |
7NMN
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![BU of 7nmn by Molmil](/molmil-images/mine/7nmn) | Rabbit HCN4 stabilised in amphipol A8-35 | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Rabbit HCN4 | Authors: | Chaves-Sanjuan, A. | Deposit date: | 2021-02-23 | Release date: | 2021-06-30 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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4TKR
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![BU of 4tkr by Molmil](/molmil-images/mine/4tkr) | Native-SAD phasing for ThiT from Listeria monocytogenes serovar. | Descriptor: | 2-O-octyl-beta-D-glucopyranose, THIAMINE DIPHOSPHATE, Thiamine transporter thia | Authors: | Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-05-27 | Release date: | 2014-06-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.0023 Å) | Cite: | Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70, 2014
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4TKQ
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![BU of 4tkq by Molmil](/molmil-images/mine/4tkq) | Native-SAD phasing for YetJ from Bacillus Subtilis | Descriptor: | CALCIUM ION, CHLORIDE ION, Uncharacterized protein YetJ | Authors: | Liu, Q, Chang, Y, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2014-05-27 | Release date: | 2014-06-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8025 Å) | Cite: | Multi-crystal native SAD analysis at 6 keV. Acta Crystallogr.,Sect.D, 70, 2014
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4TKS
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![BU of 4tks by Molmil](/molmil-images/mine/4tks) | |
1RLB
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![BU of 1rlb by Molmil](/molmil-images/mine/1rlb) | |