1H7K
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![BU of 1h7k by Molmil](/molmil-images/mine/1h7k) | Formation of a tyrosyl radical intermediate in Proteus mirabilis catalase by directed mutagenesis and consequences for nucleotide reactivity | Descriptor: | ACETATE ION, CATALASE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Andreoletti, P, Gambarelli, S, Gaillard, J, Sainz, G, Stojanoff, V, Jouve, H.M. | Deposit date: | 2001-07-08 | Release date: | 2004-02-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Formation of a Tyrosyl Radical Intermediate in Proteus Mirabilis Catalase by Directed Mutagenesis and Consequences for Nucleotide Reactivity. Biochemistry, 40, 2001
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1N8M
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![BU of 1n8m by Molmil](/molmil-images/mine/1n8m) | Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels | Descriptor: | Potassium channel blocking toxin 4 | Authors: | Guijarro, J.I, M'Barek, S, Olamendi-Portugal, T, Gomez-Lagunas, F, Garnier, D, Rochat, H, Possani, L.D, Sabatier, J.M, Delepierre, M. | Deposit date: | 2002-11-21 | Release date: | 2003-09-02 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels. Protein Sci., 12, 2003
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6HTK
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![BU of 6htk by Molmil](/molmil-images/mine/6htk) | X-ray structure of the tryptophan lyase NosL in complex with (R)-(+)-indoline-2-carboxylate | Descriptor: | 1H-indole-2-carboxylic acid, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | Authors: | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | Deposit date: | 2018-10-04 | Release date: | 2018-11-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration. J.Am.Chem.Soc., 140, 2018
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6HTO
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![BU of 6hto by Molmil](/molmil-images/mine/6hto) | Tryptophan lyase 'empty state' | Descriptor: | 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | Authors: | Amara, P, Mouesca, J.M, Bella, M, Martin, L, Saragaglia, C, Gambarelli, S, Nicolet, Y. | Deposit date: | 2018-10-04 | Release date: | 2018-11-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration. J.Am.Chem.Soc., 140, 2018
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6HTM
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![BU of 6htm by Molmil](/molmil-images/mine/6htm) | X-ray structure of the tryptophan lyase NosL in complex with bound tryptamin | Descriptor: | 2-(1H-INDOL-3-YL)ETHANAMINE, 3-methyl-2-indolic acid synthase, 5'-DEOXYADENOSINE, ... | Authors: | Amara, P, Mouesca, J.M, Bella, M, Saragaglia, C, Gambarelli, S, Nicolet, Y. | Deposit date: | 2018-10-04 | Release date: | 2018-11-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical •CO2-Migration. J.Am.Chem.Soc., 140, 2018
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3EPV
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![BU of 3epv by Molmil](/molmil-images/mine/3epv) | X-ray Structure of the Metal-sensor CnrX in both the Apo- and Copper-bound Forms | Descriptor: | COPPER (II) ION, Nickel and cobalt resistance protein cnrR | Authors: | Pompidor, G, Maillard, A.P, Girard, E, Gambarelli, S, Kahn, R, Coves, J. | Deposit date: | 2008-09-30 | Release date: | 2008-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.742 Å) | Cite: | X-ray structure of the metal-sensor CnrX in both the apo- and copper-bound forms. Febs Lett., 2008
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4OKP
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1CX5
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![BU of 1cx5 by Molmil](/molmil-images/mine/1cx5) | ANTISENSE DNA/RNA HYBRID CONTAINING MODIFIED BACKBONE | Descriptor: | 5'-D(*CP*GP*CP*GP*TP*T*(MMT)P*TP*GP*CP*GP*C), 5'-R(*GP*CP*GP*CP*AP*AP*AP*AP*CP*GP*CP*G) | Authors: | Yang, X, Han, X, Cross, C, Sanghvi, Y, Gao, X. | Deposit date: | 1999-08-28 | Release date: | 1999-09-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of an antisense DNA.RNA hybrid duplex containing a 3'-CH(2)N(CH(3))-O-5' or an MMI backbone linker. Biochemistry, 38, 1999
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2OEY
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![BU of 2oey by Molmil](/molmil-images/mine/2oey) | Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA | Descriptor: | (1R,3A'S,10'S,10A'R)-7-METHOXY-2-OXO-10',10A'-DIHYDRO-2H,3A'H-SPIRO[NAPHTHALENE-1,3'-PENTALENO[1,2-B]NAPHTHALEN]-10'-YL 2,6-DIDEOXY-2-(METHYLAMINO)-ALPHA-D-GALACTOPYRANOSIDE, DNA (25-MER) | Authors: | Zhang, N, Lin, Y, Xiao, Z, Jones, G.B, Goldberg, I.H. | Deposit date: | 2007-01-01 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA. Biochemistry, 46, 2007
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7K9Z
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![BU of 7k9z by Molmil](/molmil-images/mine/7k9z) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 298 Fab Heavy Chain, 298 Fab Light Chain, ... | Authors: | Newton, J.C, Kucharska, I, Rujas, E, Cui, H, Julien, J.P. | Deposit date: | 2020-09-29 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers. Nat Commun, 12, 2021
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1PJV
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![BU of 1pjv by Molmil](/molmil-images/mine/1pjv) | Cobatoxin 1 from Centruroides noxius Scorpion venom: Chemical Synthesis, 3-D Structure in Solution, Pharmacology and Docking on K+ channels | Descriptor: | Cobatoxin 1 | Authors: | Mosbah, A, Jouirou, B, Visan, V, Grissmer, S, El Ayeb, M, Rochat, H, De Waard, M, Mabrouk, K, Sabatier, J.M. | Deposit date: | 2003-06-03 | Release date: | 2004-03-09 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels. Biochem.J., 377, 2004
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2Z3S
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![BU of 2z3s by Molmil](/molmil-images/mine/2z3s) | NMR structure of AgTx2-MTX | Descriptor: | AgTx2-MTX | Authors: | Pimentel, C, M'Barrek, S, Visan, V, Grissmer, S, Sabatier, J.M, Darbon, H, Fajloun, Z. | Deposit date: | 2007-06-06 | Release date: | 2008-04-22 | Last modified: | 2020-02-26 | Method: | SOLUTION NMR | Cite: | Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins. Protein Sci., 17, 2008
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8DNN
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![BU of 8dnn by Molmil](/molmil-images/mine/8dnn) | Crystal structure of neutralizing antibody 80 in complex with SARS-CoV-2 receptor binding domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 80 FAB HEAVY CHAIN, 80 FAB LIGHT CHAIN, ... | Authors: | Muthuraman, K, Kucharska, I, Ivanochko, D, Julien, J.P. | Deposit date: | 2022-07-11 | Release date: | 2023-05-24 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Sci Transl Med, 15, 2023
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4JC0
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![BU of 4jc0 by Molmil](/molmil-images/mine/4jc0) | Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77 | Descriptor: | IRON/SULFUR PENTA-SULFIDE CONNECTED CLUSTERS, Ribosomal protein S12 methylthiotransferase RimO | Authors: | Forouhar, F, Hussain, M, Seetharaman, J, Fang, Y, Chen, C.X, Cunningham, K, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-02-20 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases. Nat.Chem.Biol., 9, 2013
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6FBJ
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![BU of 6fbj by Molmil](/molmil-images/mine/6fbj) | monoclonal antibody targeting Matrix metalloproteinase 7 | Descriptor: | Heavy Chain, Light chain | Authors: | Dym, O. | Deposit date: | 2017-12-19 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel monoclonal antibody targeting Matrix metalloproteinase 7 shows therapeutic potential against pancreatic cancer To Be Published
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4E3M
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4E3J
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4E3O
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![BU of 4e3o by Molmil](/molmil-images/mine/4e3o) | |
4E3L
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![BU of 4e3l by Molmil](/molmil-images/mine/4e3l) | |
4E3I
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4E3K
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4E3N
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2WTP
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![BU of 2wtp by Molmil](/molmil-images/mine/2wtp) | Crystal Structure of Cu-form Czce from C. metallidurans CH34 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Haertlein, I, Girard, E, Sarret, G, Hazemann, J, Gourhant, P, Kahn, R, Coves, J. | Deposit date: | 2009-09-18 | Release date: | 2010-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Evidence for Conformational Changes Upon Copper Binding to Cupriavidus Metallidurans Czce. Biochemistry, 49, 2010
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2Y3G
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![BU of 2y3g by Molmil](/molmil-images/mine/2y3g) | Se-Met form of Cupriavidus metallidurans CH34 CnrXs | Descriptor: | CHLORIDE ION, GLYCEROL, NICKEL AND COBALT RESISTANCE PROTEIN CNRR, ... | Authors: | Trepreau, J, Girard, E, Maillard, A.P, de Rosny, E, Petit-Haertlein, I, Kahn, R, Coves, J. | Deposit date: | 2010-12-20 | Release date: | 2011-03-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural Basis for Metal Sensing by Cnrx. J.Mol.Biol., 408, 2011
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2Y3D
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![BU of 2y3d by Molmil](/molmil-images/mine/2y3d) | Zn-bound form of Cupriavidus metallidurans CH34 CnrXs | Descriptor: | CHLORIDE ION, NICKEL AND COBALT RESISTANCE PROTEIN CNRR, ZINC ION | Authors: | Trepreau, J, Girard, E, Maillard, A.P, de Rosny, E, Petit-Haertlein, I, Kahn, R, Coves, J. | Deposit date: | 2010-12-20 | Release date: | 2011-03-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Metal Sensing by Cnrx. J.Mol.Biol., 408, 2011
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