Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77

Summary for 4JC0

DescriptorRibosomal protein S12 methylthiotransferase RimO, IRON/SULFUR PENTA-SULFIDE CONNECTED CLUSTERS (2 entities in total)
Functional Keywordsstructural genomics, psi-biology, northeast structural genomics consortium, nesg, three-domained enzyme, alpha-beta n-terminal domain, semi-tim barrel radical-sam domain, beta barrel c-terminal tram domain, ribosomal protein s12, transferase
Biological sourceThermotoga maritima
Cellular locationCytoplasm (Potential) Q9X2H6
Total number of polymer chains2
Total molecular weight102447.92
Primary citation
Forouhar, F.,Arragain, S.,Atta, M.,Gambarelli, S.,Mouesca, J.M.,Hussain, M.,Xiao, R.,Kieffer-Jaquinod, S.,Seetharaman, J.,Acton, T.B.,Montelione, G.T.,Mulliez, E.,Hunt, J.F.,Fontecave, M.
Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.
Nat.Chem.Biol., 9:333-338, 2013
PubMed: 23542644 (PDB entries with the same primary citation)
DOI: 10.1038/nchembio.1229
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.292323.1%12.3%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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