4JC0
Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006400 | biological_process | tRNA modification |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018339 | biological_process | peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid |
| A | 0035596 | molecular_function | methylthiotransferase activity |
| A | 0035599 | molecular_function | aspartic acid methylthiotransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0103039 | molecular_function | protein methylthiotransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006400 | biological_process | tRNA modification |
| B | 0016740 | molecular_function | transferase activity |
| B | 0018339 | biological_process | peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid |
| B | 0035596 | molecular_function | methylthiotransferase activity |
| B | 0035599 | molecular_function | aspartic acid methylthiotransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0103039 | molecular_function | protein methylthiotransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FS5 A 501 |
| Chain | Residue |
| A | GLY9 |
| A | ARG150 |
| A | CYS152 |
| A | CYS155 |
| A | ILE157 |
| A | GLN192 |
| A | CYS10 |
| A | LYS12 |
| A | ASN13 |
| A | CYS46 |
| A | ALA47 |
| A | PHE48 |
| A | CYS79 |
| A | CYS148 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE FS5 B 501 |
| Chain | Residue |
| B | GLY9 |
| B | CYS10 |
| B | LYS12 |
| B | ASN13 |
| B | CYS46 |
| B | ALA47 |
| B | PHE48 |
| B | CYS79 |
| B | CYS148 |
| B | ARG150 |
| B | CYS152 |
| B | PHE154 |
| B | CYS155 |
| B | ILE157 |
| B | LYS161 |
| B | GLN192 |
| B | HIS229 |
Functional Information from PROSITE/UniProt
| site_id | PS01278 |
| Number of Residues | 21 |
| Details | MTTASE_RADICAL Methylthiotransferase radical SAM domain signature. VkIsdGCdrgCTFCsIpsfkG |
| Chain | Residue | Details |
| A | VAL142-GLY162 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 462 |
| Details | Domain: {"description":"Radical SAM core","evidences":[{"source":"PROSITE-ProRule","id":"PRU01266","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 126 |
| Details | Domain: {"description":"TRAM","evidences":[{"source":"HAMAP-Rule","id":"MF_01865","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01865","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23542644","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
