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8AKN
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BU of 8akn by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome
Descriptor: 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ...
Authors:Koller, T.O, Morici, M, Wilson, D.N.
Deposit date:2022-07-30
Release date:2023-03-08
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
8ANA
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BU of 8ana by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the 50S ribosomal subunit
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, 50S ribosomal protein L13, ...
Authors:Koller, T.O, Morici, M, Wilson, D.N.
Deposit date:2022-08-05
Release date:2023-03-08
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
8AM9
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BU of 8am9 by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome
Descriptor: 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ...
Authors:Koller, T.O, Morici, M, Wilson, D.N.
Deposit date:2022-08-03
Release date:2023-03-08
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
5A06
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BU of 5a06 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with sorbitol
Descriptor: ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
5A03
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BU of 5a03 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with xylose
Descriptor: 1,4-DIETHYLENE DIOXIDE, ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
5A05
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BU of 5a05 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with maltotriose
Descriptor: ALDOSE-ALDOSE OXIDOREDUCTASE, MALONATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
5A04
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BU of 5a04 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with glucose
Descriptor: 1,4-DIETHYLENE DIOXIDE, ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
6G5J
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BU of 6g5j by Molmil
Secreted phospholipase A2 type X in complex with ligand
Descriptor: (3~{R})-3-[3-[2-aminocarbonyl-6-(trifluoromethyloxy)indol-1-yl]phenyl]butanoic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Sandmark, J, Oster, L.
Deposit date:2018-03-29
Release date:2018-09-05
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.
ACS Med Chem Lett, 9, 2018
8ACK
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BU of 8ack by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Descriptor: CACODYLATE ION, Keratinase KP1, PCP, ...
Authors:Harding, C.J, Czekster, C.M.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.784 Å)
Cite:An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACR
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BU of 8acr by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Descriptor: Keratinase KP1, SODIUM ION, ZINC ION
Authors:Harding, C.J, Czekster, C.M.
Deposit date:2022-07-06
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACG
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BU of 8acg by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T E340A mutant
Descriptor: Keratinase KP1, MAGNESIUM ION, ZINC ION
Authors:Harding, C.J, Czekster, C.M.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC7
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BU of 8ac7 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Descriptor: ACETATE ION, ISOPROPYL ALCOHOL, Keratinase KP1, ...
Authors:Harding, C.J, Czekster, C.M.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC9
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BU of 8ac9 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T
Descriptor: Keratinase KP1, ZINC ION
Authors:Harding, C.J, Czekster, C.M.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
5A02
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BU of 5a02 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with glycerol
Descriptor: ALDOSE-ALDOSE OXIDOREDUCTASE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
8SU8
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BU of 8su8 by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde).
Descriptor: (6P)-6-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-05-11
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T7V
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BU of 8t7v by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde)
Descriptor: (7M)-7-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-06-21
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T09
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BU of 8t09 by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-ethynyl-2-hydroxy-1-naphthaldehyde)
Descriptor: 6-ethynyl-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-05-31
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
3JB4
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BU of 3jb4 by Molmil
Structure of Ljungan virus: insight into picornavirus packaging
Descriptor: VP0, VP1, VP3
Authors:Zhu, L, Wang, X.X, Ren, J.S, Porta, C, Wenham, H, Ekstrom, J.-O, Panjwani, A, Knowles, N.J, Kotecha, A, Siebert, A, Lindberg, M, Fry, E.E, Rao, Z.H, Tuthill, T.J, Stuart, D.I.
Deposit date:2015-07-21
Release date:2015-10-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Ljungan virus provides insight into genome packaging of this picornavirus.
Nat Commun, 6, 2015
1U6Q
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BU of 1u6q by Molmil
Substituted 2-Naphthamadine inhibitors of Urokinase
Descriptor: TRANS-6-(2-PHENYLCYCLOPROPYL)-NAPHTHALENE-2-CARBOXAMIDINE, Urokinase-type plasminogen activator
Authors:Bruncko, M, McClellan, W, Wendt, M.D, Sauer, D.R, Geyer, A, Dalton, C.R, Kaminski, M.K, Nienaber, V.L, Rockway, T.R, Giranda, V.L.
Deposit date:2004-07-30
Release date:2004-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties.
Bioorg.Med.Chem.Lett., 15, 2005
3G7K
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BU of 3g7k by Molmil
Crystal Structure of Methylitaconate-delta-isomerase
Descriptor: 3-methylitaconate isomerase
Authors:Messerschmidt, A, Macieira, S, Velarde, M.
Deposit date:2009-02-10
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and putative mechanism of 3-methylitaconate-delta-isomerase from Eubacterium barkeri
J.Mol.Biol., 391, 2009
2J4R
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BU of 2j4r by Molmil
Structural Study of the Aquifex aeolicus PPX-GPPA enzyme
Descriptor: EXOPOLYPHOSPHATASE, GUANOSINE-5',3'-TETRAPHOSPHATE
Authors:Kristensen, O.
Deposit date:2006-09-05
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structure of the Ppx/Gppa Phosphatase from Aquifex Aeolicus in Complex with the Alarmone Ppgpp
J.Mol.Biol., 375, 2008
2CFI
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BU of 2cfi by Molmil
The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin
Descriptor: 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, 6-FORMYLTETRAHYDROPTERIN, SULFATE ION
Authors:Kursula, P, Stenmark, P, Arrowsmith, C, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D.J, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J.
Deposit date:2006-02-21
Release date:2006-03-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D, 62, 2006
2BW0
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BU of 2bw0 by Molmil
Crystal Structure of the hydrolase domain of Human 10-Formyltetrahydrofolate 2 dehydrogenase
Descriptor: 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, SULFATE ION
Authors:Ogg, D.J, Stenmark, P, Arrowsmith, C, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Dobritzsch, D, Weigelt, J.
Deposit date:2005-07-07
Release date:2005-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D, 62, 2006
7AMF
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BU of 7amf by Molmil
Crystal structure of rsFolder2 in its non-fluorescent off-state
Descriptor: GLYCEROL, Green fluorescent protein
Authors:Moreno-Chicano, T, El Khatib, M, Colletier, J.-P.
Deposit date:2020-10-08
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Rational Control of Off-State Heterogeneity in a Photoswitchable Fluorescent Protein Provides Switching Contrast Enhancement.
Chemphyschem, 23, 2022
7AMB
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BU of 7amb by Molmil
Crystal structure of rsFolder2 in its fluorescent on-state
Descriptor: GLYCEROL, Green fluorescent protein
Authors:Moreno-Chicano, T, El Khatib, M, Colletier, J.-P.
Deposit date:2020-10-08
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Rational Control of Off-State Heterogeneity in a Photoswitchable Fluorescent Protein Provides Switching Contrast Enhancement.
Chemphyschem, 23, 2022

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數據於2024-07-10公開中

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