2F13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f13 by Molmil](/molmil-images/mine/2f13) | Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor | Descriptor: | (2R)-2,3-dihydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-14 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor To be Published
|
|
2F11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f11 by Molmil](/molmil-images/mine/2f11) | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor | Descriptor: | 2-methylpropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-14 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor To be Published
|
|
1N68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n68 by Molmil](/molmil-images/mine/1n68) | Copper bound to the Multicopper Oxidase CueO | Descriptor: | Blue copper oxidase cueO, COPPER (II) ION, CU-CL-CU LINKAGE | Authors: | Roberts, S.A, Wildner, G.F, Grass, G, Weichsel, A, Ambrus, A, Rensing, C, Montfort, W.R. | Deposit date: | 2002-11-08 | Release date: | 2003-06-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Labile Regulatory Copper Ion Lies Near the T1 Copper Site in the Multicopper Oxidase CueO. J.Biol.Chem., 278, 2003
|
|
1DSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dsl by Molmil](/molmil-images/mine/1dsl) | GAMMA B CRYSTALLIN C-TERMINAL DOMAIN | Descriptor: | GAMMA B CRYSTALLIN | Authors: | Norledge, B.V, Mayr, E.-M, Glockshuber, R, Bateman, O.A, Slingsby, C, Jaenicke, R, Driessen, H.P.C. | Deposit date: | 1996-02-01 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins. Nat.Struct.Biol., 3, 1996
|
|
2F26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f26 by Molmil](/molmil-images/mine/2f26) | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant | Descriptor: | CHLORIDE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant To be Published
|
|
2F0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f0z by Molmil](/molmil-images/mine/2f0z) | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor | Descriptor: | Sialidase 2, ZANAMIVIR | Authors: | Chavas, L.M.G, Kato, R, McKimm-Breschkin, J, Colman, P.M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-14 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor To be Published
|
|
2F25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f25 by Molmil](/molmil-images/mine/2f25) | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor To be Published
|
|
2F24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f24 by Molmil](/molmil-images/mine/2f24) | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant | Descriptor: | CHLORIDE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant To be Published
|
|
2L8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l8i by Molmil](/molmil-images/mine/2l8i) | A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA duplex | Descriptor: | DNA (5'-D(*CP*GP*AP*CP*G*(2L8)P*TP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3') | Authors: | El-Sagheer, A, Brown, T, Ernsting, N, Dehmel, L, Griesinger, C, Mugge, C. | Deposit date: | 2011-01-13 | Release date: | 2011-12-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of Triazole-Linked DNA: Biocompatibility Explained. Chemistry, 17, 2011
|
|
2F29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f29 by Molmil](/molmil-images/mine/2f29) | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.921 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor To be Published
|
|
2F12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f12 by Molmil](/molmil-images/mine/2f12) | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor | Descriptor: | 3-hydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-14 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor To be Published
|
|
2F28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f28 by Molmil](/molmil-images/mine/2f28) | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant | Descriptor: | CHLORIDE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant To be Published
|
|
2F27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f27 by Molmil](/molmil-images/mine/2f27) | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-15 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor To be Published
|
|
2QIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qif by Molmil](/molmil-images/mine/2qif) | Crystal structure of a metallochaperone with a tetranuclear Cu(I) cluster | Descriptor: | ACETATE ION, CALCIUM ION, COPPER (I) ION, ... | Authors: | West, C, Singleton, C, Kihlken, M.A, Le Brun, N.E, Hemmings, A.M. | Deposit date: | 2007-07-04 | Release date: | 2008-07-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A tetranuclear Cu(I) cluster in the metallochaperone protein CopZ. Biochemistry, 48, 2009
|
|
1PKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pkq by Molmil](/molmil-images/mine/1pkq) | Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex | Descriptor: | (8-18C5) chimeric Fab, heavy chain, light chain, ... | Authors: | Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2003-06-06 | Release date: | 2003-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
2K39
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k39 by Molmil](/molmil-images/mine/2k39) | Recognition dynamics up to microseconds revealed from RDC derived ubiquitin ensemble in solution | Descriptor: | Ubiquitin | Authors: | Lange, O.F, Lakomek, N.A, Fares, C, Schroder, G, Walter, K, Becker, S, Meiler, J, Grubmuller, H, Griesinger, C, de Groot, B.L. | Deposit date: | 2008-04-25 | Release date: | 2008-06-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science, 320, 2008
|
|
2Y8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y8q by Molmil](/molmil-images/mine/2y8q) | Structure of the regulatory fragment of mammalian AMPK in complex with one ADP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ... | Authors: | Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J. | Deposit date: | 2011-02-09 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Mammalian Ampk and its Regulation by Adp Nature, 472, 2011
|
|
6ET8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6et8 by Molmil](/molmil-images/mine/6et8) | Crystal structure of AlbA in complex with albicidin | Descriptor: | Albicidin resistance protein, SULFATE ION, albicidin | Authors: | Driller, R, Rostock, L, Alings, C, Graetz, S, Suessmuth, R, Mainz, A, Wahl, M.C, Loll, B. | Deposit date: | 2017-10-25 | Release date: | 2018-08-15 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular insights into antibiotic resistance - how a binding protein traps albicidin. Nat Commun, 9, 2018
|
|
2Y8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y8l by Molmil](/molmil-images/mine/2y8l) | Structure of the regulatory fragment of mammalian aMPK in complex with two ADP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ... | Authors: | Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J. | Deposit date: | 2011-02-07 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Mammalian Ampk and its Regulation by Adp Nature, 472, 2011
|
|
2YA3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ya3 by Molmil](/molmil-images/mine/2ya3) | STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP | Descriptor: | 3'-(7-diethylaminocoumarin-3-carbonylamino)-3'-deoxy-ADP, 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, ... | Authors: | Xiao, B, Sanders, M.J, Underwood, E, Heath, R, Mayer, F, Carmena, D, Jing, C, Walker, P.A, Eccleston, J.F, Haire, L.F, Saiu, P, Howell, S.A, Aasland, R, Martin, S.R, Carling, D, Gamblin, S.J. | Deposit date: | 2011-02-17 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of Mammalian Ampk and its Regulation by Adp Nature, 472, 2011
|
|
6F2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f2r by Molmil](/molmil-images/mine/6f2r) | A heterotetramer of human HspB2 and HspB3 | Descriptor: | Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, ... | Authors: | Clark, A.R, Cole, A.R, Boelens, W.C, Keep, N.H, Slingsby, C. | Deposit date: | 2017-11-27 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3. J.Mol.Biol., 430, 2018
|
|
2N64
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n64 by Molmil](/molmil-images/mine/2n64) | |
1O9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o9j by Molmil](/molmil-images/mine/1o9j) | The X-ray crystal structure of eta-crystallin | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ALDEHYDE DEHYDROGENASE, ... | Authors: | Purkiss, A.G, Van Montfort, R, Wistow, G, Slingsby, C. | Deposit date: | 2002-12-15 | Release date: | 2003-04-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Eta-Crystallin: Adaptation of a Class 1 Aldehyde Dehydrogenase for a New Role in the Eye Lens Biochemistry, 42, 2003
|
|
1GME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gme by Molmil](/molmil-images/mine/1gme) | Crystal structure and assembly of an eukaryotic small heat shock protein | Descriptor: | HEAT SHOCK PROTEIN 16.9B | Authors: | Van Montfort, R.L.M, Basha, E, Friedrich, K.L, Slingsby, C, Vierling, E. | Deposit date: | 2001-09-13 | Release date: | 2001-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure and Assembly of an Eukaryotic Small Heat Shock Protein Nat.Struct.Biol., 8, 2001
|
|
7UUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uur by Molmil](/molmil-images/mine/7uur) | The 1.67 Angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - catalytic dimer (Huc2S2L) | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, HYDROXIDE ION, ... | Authors: | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | Deposit date: | 2022-04-28 | Release date: | 2023-01-04 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
|
|