A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA duplex

Summary for 2L8I

DescriptorDNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*CP*G*(2L8)P*TP*GP*CP*AP*GP*C)-3') (2 entities in total)
Functional Keywordsdna
Total number of polymer chains2
Total molecular weight7945.28
El-Sagheer, A.,Brown, T.,Ernsting, N.,Dehmel, L.,Griesinger, C.,Mugge, C. (deposition date: 2011-01-13, release date: 2011-12-28)
Primary citation
Dallmann, A.,El-Sagheer, A.H.,Dehmel, L.,Mugge, C.,Griesinger, C.,Ernsting, N.P.,Brown, T.
Structure and Dynamics of Triazole-Linked DNA: Biocompatibility Explained.
Chemistry, 17:14714-14717, 2011
PubMed: 22131102 (PDB entries with the same primary citation)
DOI: 10.1002/chem.201102979
MImport into Mendeley
Experimental method
NMR Information

Structure validation

Clashscore6MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2l8i
no rotation
Molmil generated image of 2l8i
rotated about x axis by 90°
Molmil generated image of 2l8i
rotated about y axis by 90°