9FX0
 
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9FW9
 | | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (FimDHGFAnC - body 2) | | Descriptor: | Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ... | | Authors: | Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R. | | Deposit date: | 2024-06-28 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (FimDHGFAnC - body 2)
To Be Published
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9FWZ
 | | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn, FimAn-1 and FimAn-2) | | Descriptor: | Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ... | | Authors: | Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R. | | Deposit date: | 2024-07-01 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn, FimAn-1 and FimAn-2)
To Be Published
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9FWB
 | | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn and FimAn-1) | | Descriptor: | Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ... | | Authors: | Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R. | | Deposit date: | 2024-06-28 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn and FimAn-1)
To Be Published
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9FXB
 | | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimI-bound chaperone-usher pilus complex (FimDHGFAnIC - body 2) | | Descriptor: | Chaperone protein FimC, Fimbrin-like protein FimI, Outer membrane usher protein FimD, ... | | Authors: | Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R. | | Deposit date: | 2024-07-01 | | Release date: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM structure of the type 1 pilus assembly platform as part of the FimI-bound chaperone-usher pilus complex (FimDHGFAnIC - body 2)
To Be Published
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5MMI
 | | Structure of the large subunit of the chloroplast ribosome | | Descriptor: | 23S ribosomal RNA, 4.5S ribosomal RNA, 50S ribosomal protein 6, ... | | Authors: | Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. | | Deposit date: | 2016-12-10 | | Release date: | 2017-01-11 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
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5O61
 | | The complete structure of the Mycobacterium smegmatis 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N. | | Deposit date: | 2017-06-03 | | Release date: | 2017-07-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | The Complete Structure of the Mycobacterium smegmatis 70S Ribosome.
Cell Rep, 20, 2017
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9FTT
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9FNE
 | | Mycobacterial PafBC-bound transcription initiation complex | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Zdanowicz, R, Schilling, C.M, Rabl, J, Mueller, A.U, Boehringer, D, Glockshuber, R, Weber-Ban, E. | | Deposit date: | 2024-06-10 | | Release date: | 2025-02-12 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Single-stranded DNA binding to the transcription factor PafBC triggers the mycobacterial DNA damage response.
Sci Adv, 11, 2025
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9FND
 | | Transcriptional activator PafBC bound to mycobacterial RNA polymerase | | Descriptor: | PafC, Transcriptional regulator-like protein | | Authors: | Zdanowicz, R, Schilling, C.M, Rabl, J, Mueller, A.U, Boehringer, D, Glockshuber, R, Weber-Ban, E. | | Deposit date: | 2024-06-10 | | Release date: | 2025-02-12 | | Last modified: | 2025-02-19 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Single-stranded DNA binding to the transcription factor PafBC triggers the mycobacterial DNA damage response.
Sci Adv, 11, 2025
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5MMJ
 | | Structure of the small subunit of the chloroplast ribosome | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein 2, chloroplastic, ... | | Authors: | Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. | | Deposit date: | 2016-12-10 | | Release date: | 2017-01-11 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
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4CE4
 | | 39S large subunit of the porcine mitochondrial ribosome | | Descriptor: | 16S Ribosomal RNA, ICT1, MRPL13, ... | | Authors: | Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N. | | Deposit date: | 2013-11-08 | | Release date: | 2013-12-18 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Nature, 505, 2014
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4ADX
 | | The Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 | | Descriptor: | 23S Ribosomal RNA EXPANSION SEGMENTS, 23S ribosomal RNA, 5S Ribosomal RNA, ... | | Authors: | Greber, B.J, Boehringer, D, Godinic-Mikulcic, V, Crnkovic, A, Ibba, M, Weygand-Durasevic, I, Ban, N. | | Deposit date: | 2012-01-04 | | Release date: | 2012-02-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Cryo-Em Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution
J.Mol.Biol., 418, 2012
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1L6G
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine | | Descriptor: | N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase | | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | Deposit date: | 2002-03-10 | | Release date: | 2002-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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1L6F
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine | | Descriptor: | ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase | | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | Deposit date: | 2002-03-09 | | Release date: | 2002-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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8CCX
 | | Human SOD1 in complex with S-XL6 cross-linker | | Descriptor: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | | Authors: | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | Deposit date: | 2023-01-27 | | Release date: | 2023-12-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.665 Å) | | Cite: | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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8Q6M
 | | Human SOD1 low dose data collecton | | Descriptor: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | | Authors: | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | Deposit date: | 2023-08-14 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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1YAA
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2VGC
 | | GAMMA-CHYMOTRYPSIN D-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | | Descriptor: | D-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | | Deposit date: | 1997-05-01 | | Release date: | 1997-11-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
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5VWR
 | | E.coli Aspartate aminotransferase-(1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP)-alpha-ketoglutarate | | Descriptor: | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, Aspartate aminotransferase, GLYCEROL | | Authors: | Mascarenhas, R, Liu, D, Le, H, Silverman, R. | | Deposit date: | 2017-05-22 | | Release date: | 2017-09-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Biochemistry, 56, 2017
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5VWO
 | | Ornithine aminotransferase inactivated by (1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP) | | Descriptor: | (1S,3S,4E)-3-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-4-iminocyclopentane-1-carboxylic acid, Ornithine aminotransferase, mitochondrial | | Authors: | Mascarenhas, R, Liu, D, Le, H, Silverman, R. | | Deposit date: | 2017-05-22 | | Release date: | 2017-08-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.773 Å) | | Cite: | Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Biochemistry, 56, 2017
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4VGC
 | | GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | | Descriptor: | D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION | | Authors: | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | | Deposit date: | 1997-05-01 | | Release date: | 1997-11-12 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
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4MPP
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3YPI
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3OWS
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