4AWG
 
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3 | | Descriptor: | (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA, ... | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-06-03 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4CEK
 | | Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2 | | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 2 | | Authors: | Clerici, M, Deniaud, A, Boehm, V, Gehring, N.H, Schaffitzel, C, Cusack, S. | | Deposit date: | 2013-11-11 | | Release date: | 2013-12-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2.
Nucleic Acids Res., 42, 2014
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4CHC
 | | Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2) | | Descriptor: | POLYMERASE ACIDIC PROTEIN | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-12-01 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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4AQ7
 | | Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation | | Descriptor: | E. COLI TRNALEU UAA ISOACCEPTOR, LEUCINE, LEUCINE--TRNA LIGASE, ... | | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | | Deposit date: | 2012-04-13 | | Release date: | 2012-06-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
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4A2V
 | | Structure of duck RIG-I C-terminal domain (CTD) | | Descriptor: | GLYCEROL, RETINOIC ACID INDUCIBLE PROTEIN I, ZINC ION | | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | Deposit date: | 2011-09-29 | | Release date: | 2011-10-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Cell(Cambridge,Mass.), 147, 2011
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4AR2
 | | Dodecahedron formed of penton base protein from adenovirus Ad3 | | Descriptor: | CALCIUM ION, FIBER PROTEIN, L2 PROTEIN III (PENTON BASE) | | Authors: | Burmeister, W.P, Szolajska, E, Zochowska, M, Nerlo, B, Andreev, I, Schoehn, G, Andrieu, J.-P, Fender, P, Naskalska, A, Zubieta, C, Cusack, S, Chroboczek, J. | | Deposit date: | 2012-04-20 | | Release date: | 2012-10-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron.
Plos One, 7, 2012
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4A2X
 | | Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA | | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*UP*GP*UP*UP*CP*UP*CP*CP*CP)-3', 5'-R(*GP*GP*GP*AP*GP*AP*AP*CP*AP*AP*CP*GP*CP*GP)-3', RETINOIC ACID INDUCIBLE PROTEIN I, ... | | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | Deposit date: | 2011-09-29 | | Release date: | 2011-10-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.
Cell, 147, 2011
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4A36
 | | Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue | | Descriptor: | 5'-R(*GP*CP*AP*UP*GP*CP*GP*AP*CP*CP*UP*CP*UP*GP *UP*UP*UP*GP*A)-3', 5'-R(*UP*CP*AP*AP*AP*CP*AP*GP*AP*GP*GP*UP*CP*GP *CP*AP*UP*GP*C)-3', ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | Deposit date: | 2011-09-30 | | Release date: | 2011-10-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Cell(Cambridge,Mass.), 147, 2011
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4CHD
 | | Crystal structure of the '627' domain of the PB2 subunit of Thogoto virus polymerase | | Descriptor: | POLYMERASE ACIDIC PROTEIN | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-12-01 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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4AS1
 | | Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation | | Descriptor: | LEUCINE--TRNA LIGASE, MAGNESIUM ION, TRNA-LEU5 (UAA ISOACEPTOR) | | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | | Deposit date: | 2012-04-27 | | Release date: | 2012-06-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
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4CQN
 | | Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue | | Descriptor: | ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | | Authors: | Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I. | | Deposit date: | 2014-02-20 | | Release date: | 2014-07-02 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Physiological Target for Leurs Translational Quality Control is Norvaline
Embo J., 33, 2014
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3ZIU
 | | Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site | | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, LEUCYL-TRNA SYNTHETASE | | Authors: | Li, L, Palencia, A, Lukk, T, Li, Z, Luthey-Schulten, Z.A, Cusack, S, Martinis, S.A, Boniecki, M.T. | | Deposit date: | 2013-01-10 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4CGX
 | | Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 1) | | Descriptor: | POLYMERASE ACIDIC PROTEIN | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-11-27 | | Release date: | 2014-02-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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4CY1
 | | Crystal structure of the KANSL1-WDR5 complex. | | Descriptor: | GLYCEROL, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, WD REPEAT-CONTAINING PROTEIN 5 | | Authors: | Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. | | Deposit date: | 2014-04-09 | | Release date: | 2014-05-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
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4A2W
 | | Structure of full-length duck RIG-I | | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | Deposit date: | 2011-09-29 | | Release date: | 2011-10-19 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Cell(Cambridge,Mass.), 147, 2011
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4AWH
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with rUMP | | Descriptor: | MANGANESE (II) ION, POLYMERASE PA, URIDINE-5'-MONOPHOSPHATE | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-06-03 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4AVL
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP | | Descriptor: | MANGANESE (II) ION, POLYMERASE PA, THYMIDINE-5'-PHOSPHATE | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H.J, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2012-05-28 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4CY2
 | | Crystal structure of the KANSL1-WDR5-KANSL2 complex. | | Descriptor: | KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, WD REPEAT-CONTAINING PROTEIN 5 | | Authors: | Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. | | Deposit date: | 2014-04-09 | | Release date: | 2014-05-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
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4CGS
 | | Crystal structure of the N-terminal domain of the PA subunit of Dhori virus polymerase | | Descriptor: | GLYCEROL, POLYMERASE SUBUNIT PA | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-11-26 | | Release date: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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4CHF
 | | Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase (form 2) | | Descriptor: | POLYMERASE BASIC PROTEIN 2 | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-12-01 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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4A2Q
 | | Structure of duck RIG-I tandem CARDs and helicase domain | | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | | Deposit date: | 2011-09-28 | | Release date: | 2011-10-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Cell(Cambridge,Mass.), 147, 2011
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4CY3
 | | Crystal structure of the NSL1-WDS complex. | | Descriptor: | CG4699, ISOFORM D, GLYCEROL, ... | | Authors: | Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. | | Deposit date: | 2014-04-10 | | Release date: | 2014-05-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
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4CY5
 | | Crystal structure of the NSL1-WDS-NSL2 complex. | | Descriptor: | CG4699, ISOFORM D, DIM GAMMA-TUBULIN 1, ... | | Authors: | Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. | | Deposit date: | 2014-04-10 | | Release date: | 2014-05-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
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4CHE
 | | Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase | | Descriptor: | POLYMERASE BASIC PROTEIN 2 | | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2013-12-01 | | Release date: | 2014-02-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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1EJD
 | | Crystal structure of unliganded mura (type1) | | Descriptor: | CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE | | Authors: | Eschenburg, S, Schonbrunn, E. | | Deposit date: | 2000-03-02 | | Release date: | 2000-10-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
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