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3SZ9
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BU of 3sz9 by Molmil
Crystal structure of human ALDH2 modified with the beta-elimination product of Aldi-3; 1-(4-ethylbenzene)prop-2-en-1-one
Descriptor: 1,2-ETHANEDIOL, 1-(4-ethylphenyl)propan-1-one, Aldehyde dehydrogenase, ...
Authors:Perez-Miller, S, Hurley, T.D.
Deposit date:2011-07-18
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
J.Biol.Chem., 286, 2011
3UPX
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BU of 3upx by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1300
Descriptor: Calmodulin-domain protein kinase 1, [2-amino-1-(piperidin-4-ylmethyl)-1H-benzimidazol-6-yl](phenyl)methanone
Authors:Merritt, E.A, Larson, E.T.
Deposit date:2011-11-18
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
2R7E
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BU of 2r7e by Molmil
Crystal Structure Analysis of Coagulation Factor VIII
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
Authors:Stoddard, B.L, Shen, B.W.
Deposit date:2007-09-07
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The tertiary structure and domain organization of coagulation factor VIII.
Blood, 111, 2008
6A4V
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BU of 6a4v by Molmil
Open Reading frame 49
Descriptor: 49 protein
Authors:Hwang, K.Y, Song, M.J, Kim, J.S, Cheong, W.C.
Deposit date:2018-06-21
Release date:2019-06-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based mechanism of action of a viral poly(ADP-ribose) polymerase 1-interacting protein facilitating virus replication.
Iucrj, 5, 2018
8IU0
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BU of 8iu0 by Molmil
Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 H225F mutant in lipid nanodisc
Descriptor: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR1, PALMITIC ACID, ...
Authors:Tajima, S, Kim, Y, Nakamura, S, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E.
Deposit date:2023-03-23
Release date:2023-09-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural basis for ion selectivity in potassium-selective channelrhodopsins.
Cell, 186, 2023
2VXP
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BU of 2vxp by Molmil
The fourth FAS1 domain structure of human Bigh3
Descriptor: TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3
Authors:Yoo, J.-H, Cho, H.-S.
Deposit date:2008-07-08
Release date:2009-07-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structural Analysis of the Fas1 Domain 4 of Big-H3 for Relationship with Corneal Dystrophy
To be Published
5SY1
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BU of 5sy1 by Molmil
Structure of the STRA6 receptor for retinol uptake in complex with calmodulin
Descriptor: CALCIUM ION, CHOLESTEROL, Calmodulin, ...
Authors:Clarke, O.B, Chen, Y, Mancia, F.
Deposit date:2016-08-10
Release date:2016-08-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
8H86
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BU of 8h86 by Molmil
Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 in lipid nanodisc
Descriptor: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR1, PALMITIC ACID, ...
Authors:Tajima, S, Kim, Y, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E.
Deposit date:2022-10-21
Release date:2023-09-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Structural basis for ion selectivity in potassium-selective channelrhodopsins.
Cell, 186, 2023
8H87
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BU of 8h87 by Molmil
Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR2 in lipid nanodisc
Descriptor: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR2, PALMITIC ACID, ...
Authors:Tajima, S, Kim, Y, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E.
Deposit date:2022-10-21
Release date:2023-09-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural basis for ion selectivity in potassium-selective channelrhodopsins.
Cell, 186, 2023
3V51
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BU of 3v51 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor RM-1-176
Descriptor: 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A, Larson, E.T.
Deposit date:2011-12-15
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
3V5P
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BU of 3v5p by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1288
Descriptor: 3-(4-methoxy-3-methylphenyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A, Larson, E.T.
Deposit date:2011-12-16
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
4R1N
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BU of 4r1n by Molmil
Crystal structure of (S)-3-hydroxybutylryl-CoA dehydrogenase form the n-butanol sysnthesizing bacterium, Clostridium butyricum.
Descriptor: 3-hydroxybutyryl-CoA dehydrogenase
Authors:Kim, E.J, Kim, S.W, Kim, K.J.
Deposit date:2014-08-07
Release date:2015-07-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium butyricum and its mutations that enhance reaction kinetics
J MICROBIOL BIOTECHNOL., 24, 2014
4Y5Q
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BU of 4y5q by Molmil
Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CALCIUM ION, Calmodulin-domain protein kinase 1, ...
Authors:Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2015-02-11
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
To Be Published
4K86
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BU of 4k86 by Molmil
Crystal structure of human prolyl-tRNA synthetase (apo form)
Descriptor: Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
4OWI
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BU of 4owi by Molmil
peptide structure
Descriptor: p53LZ2
Authors:Lee, J.-H.
Deposit date:2014-02-02
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
Nat Commun, 5, 2014
4K87
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BU of 4k87 by Molmil
Crystal structure of human prolyl-tRNA synthetase (substrate bound form)
Descriptor: ADENOSINE, PROLINE, Proline--tRNA ligase, ...
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
3P2F
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BU of 3p2f by Molmil
Crystal structure of TofI in an apo form
Descriptor: AHL synthase
Authors:Yu, S, Rhee, S.
Deposit date:2010-10-02
Release date:2011-07-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
3P2H
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BU of 3p2h by Molmil
Crystal structure of TofI in a ternary complex with an inhibitor and MTA
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, AHL synthase, N-(3-oxocyclohex-1-en-1-yl)octanamide
Authors:Yu, S, Rhee, S.
Deposit date:2010-10-02
Release date:2011-07-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
4K88
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BU of 4k88 by Molmil
Crystal structure of human prolyl-tRNA synthetase (halofuginone bound form)
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
5F3K
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BU of 5f3k by Molmil
X-Ray Crystallographic Structure of hTrap1 N-terminal Domain-apo
Descriptor: Heat shock protein 75 kDa, mitochondrial
Authors:Sung, N, Lee, J, Kim, J, Chang, C, Joachimiak, A, Lee, S, Tsai, F.T.F.
Deposit date:2015-12-02
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
3RIG
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BU of 3rig by Molmil
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, NAD-dependent deacetylase sirtuin-5, ZINC ION, ...
Authors:Zhou, Y.
Deposit date:2011-04-13
Release date:2011-11-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
Science, 334, 2011
2GJL
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BU of 2gjl by Molmil
Crystal Structure of 2-nitropropane dioxygenase
Descriptor: FLAVIN MONONUCLEOTIDE, hypothetical protein PA1024
Authors:Suh, S.W.
Deposit date:2006-03-31
Release date:2006-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate: identification of the catalytic base
J.Biol.Chem., 281, 2006
3RIY
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BU of 3riy by Molmil
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase
Descriptor: NAD-dependent deacetylase sirtuin-5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, ...
Authors:Zhou, Y, Hao, Q.
Deposit date:2011-04-14
Release date:2011-11-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
Science, 334, 2011
2GJN
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BU of 2gjn by Molmil
crystal structure of 2-nitropropane dioxygenase complexed with FMN and substrate
Descriptor: 2-NITROPROPANE, FLAVIN MONONUCLEOTIDE, hypothetical protein PA1024
Authors:Suh, S.W.
Deposit date:2006-03-31
Release date:2006-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate: identification of the catalytic base
J.Biol.Chem., 281, 2006
8FBW
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BU of 8fbw by Molmil
Crystal structure of SIV-1 V2 antibody NCI05 in complex with a V2 peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Zhou, T, Kwong, P.D, Van Wazer, D.J.
Deposit date:2022-11-30
Release date:2023-01-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Effect of Passive Administration of Monoclonal Antibodies Recognizing Simian Immunodeficiency Virus (SIV) V2 in CH59-Like Coil/Helical or beta-Sheet Conformations on Time of SIV mac251 Acquisition.
J.Virol., 97, 2023

224004

數據於2024-08-21公開中

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