8IU0

Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 H225F mutant in lipid nanodisc

Summary for 8IU0

Entry DOI	10.2210/pdb8iu0/pdb
EMDB information	35713
Descriptor	HcKCR1, RETINAL, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... (5 entities in total)
Functional Keywords	membrane protein, cryo-em
Biological source	Hyphochytrium catenoides
Total number of polymer chains	1
Total formula weight	40309.61
Authors	Tajima, S.,Kim, Y.,Nakamura, S.,Yamashita, K.,Fukuda, M.,Deisseroth, K.,Kato, H.E. (deposition date: 2023-03-23, release date: 2023-09-06, Last modification date: 2024-05-01)
Primary citation	Tajima, S.,Kim, Y.S.,Fukuda, M.,Jo, Y.,Wang, P.Y.,Paggi, J.M.,Inoue, M.,Byrne, E.F.X.,Kishi, K.E.,Nakamura, S.,Ramakrishnan, C.,Takaramoto, S.,Nagata, T.,Konno, M.,Sugiura, M.,Katayama, K.,Matsui, T.E.,Yamashita, K.,Kim, S.,Ikeda, H.,Kim, J.,Kandori, H.,Dror, R.O.,Inoue, K.,Deisseroth, K.,Kato, H.E. Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell, 186:4325-4344.e26, 2023 Cited by PubMed: 37652010 DOI: 10.1016/j.cell.2023.08.009 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.66 Å)

Structure validation