2ODA
| Crystal Structure of PSPTO_2114 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hypothetical protein PSPTO_2114, MAGNESIUM ION | Authors: | Peisach, E, Allen, K.N, Dunaway-Mariano, D, Wang, L, Burroughs, A.M, Aravind, L. | Deposit date: | 2006-12-22 | Release date: | 2007-09-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The X-ray crystallographic structure and activity analysis of a Pseudomonas-specific subfamily of the HAD enzyme superfamily evidences a novel biochemical function. Proteins, 70, 2007
|
|
4PIV
| Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and GSK2194069 | Descriptor: | 4-[4-(1-benzofuran-5-yl)phenyl]-5-{[(3S)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, CACODYLATE ION, Fatty acid synthase, ... | Authors: | Williams, S.P, Wang, L, Brown, K.K, Parrish, C.A, Hardwicke, M.A. | Deposit date: | 2014-05-09 | Release date: | 2014-07-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site. Nat.Chem.Biol., 10, 2014
|
|
7XXG
| Echo 18 at pH5.5 | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-30 | Release date: | 2022-06-29 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
|
|
7XXJ
| Echo 18 incubated with FcRn at pH5.5 | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-30 | Release date: | 2022-06-29 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
|
|
7XXA
| Complex of Echo 18 and FcRn at pH7.4 | Descriptor: | IgG receptor FcRn large subunit p51, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-29 | Release date: | 2022-06-29 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
|
|
3Q32
| Structure of Janus kinase 2 with a pyrrolotriazine inhibitor | Descriptor: | 2-(2,6-difluoro-4-methoxyphenyl)-1-(4-{4-[(3-methyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}piperazin-1-yl)ethanone, Tyrosine-protein kinase JAK2 | Authors: | Sack, J.S. | Deposit date: | 2010-12-21 | Release date: | 2011-02-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Bioorg.Med.Chem.Lett., 21, 2011
|
|
3VMV
| Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 | Descriptor: | Pectate lyase, SULFATE ION | Authors: | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | Deposit date: | 2011-12-16 | Release date: | 2012-07-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5. Biochem.Biophys.Res.Commun., 420, 2012
|
|
3VMW
| Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 in complex with trigalacturonate | Descriptor: | Pectate lyase, SULFATE ION, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | Authors: | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | Deposit date: | 2011-12-17 | Release date: | 2012-07-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5. Biochem.Biophys.Res.Commun., 420, 2012
|
|
7DSY
| Crystal Structure of RNase L in complex with KM05073 | Descriptor: | 1-chloranyl-3-methylsulfinyl-6,7-dihydro-5H-2-benzothiophen-4-one, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, PHOSPHATE ION, ... | Authors: | Tang, J, Huang, H. | Deposit date: | 2021-01-03 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery J.Med.Chem., 65, 2022
|
|
7DTS
| Crystal structure of RNase L in complex with AC40357 | Descriptor: | 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, PHOSPHATE ION, Ribonuclease L, ... | Authors: | Tang, J, Huang, H. | Deposit date: | 2021-01-06 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery J.Med.Chem., 65, 2022
|
|
7ELW
| Crystal structure of RNase L in complex with Myricetin | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PHOSPHATE ION, Ribonuclease L, ... | Authors: | Tang, J, Huang, H. | Deposit date: | 2021-04-12 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery J.Med.Chem., 65, 2022
|
|
3UGD
| Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ... | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | Deposit date: | 2011-11-02 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Biophys.J., 103, 2012
|
|
7CJM
| SARS CoV-2 PLpro in complex with GRL0617 | Descriptor: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION | Authors: | Fu, Z, Huang, H. | Deposit date: | 2020-07-11 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery. Nat Commun, 12, 2021
|
|
1QT1
| |
1TBN
| NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE | Descriptor: | PROTEIN KINASE C, GAMMA TYPE, ZINC ION | Authors: | Xu, R.X, Pawelczyk, T, Xia, T, Brown, S.C. | Deposit date: | 1997-04-15 | Release date: | 1998-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions. Biochemistry, 36, 1997
|
|
1TBO
| NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, 30 STRUCTURES | Descriptor: | PROTEIN KINASE C, GAMMA TYPE, ZINC ION | Authors: | Xu, R.X, Pawelczyk, T, Xia, T, Brown, S.C. | Deposit date: | 1997-04-15 | Release date: | 1998-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions. Biochemistry, 36, 1997
|
|