7UJI
| |
7VYO
| The structure of GdmN | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wei, J, Zheng, J, Zhou, J, Kang, Q, Bai, L. | Deposit date: | 2021-11-14 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies. Nat Commun, 13, 2022
|
|
7YOO
| Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kang, H, Park, C, Kim, J, Choi, H.-J. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
|
|
8FOI
| Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with GABA and allopregnanolone | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, DODECANE, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2022-12-30 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G4X
| Native GABA-A receptor from the mouse brain, meta-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA and allopregnanolone | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-10 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G5H
| Native GABA-A receptor from the mouse brain, ortho-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA, Zolpidem, and endogenous neurosteroid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-13 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G5F
| Native GABA-A receptor from the mouse brain, ortho-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA and allopregnanolone | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-13 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G5G
| Native GABA-A receptor from the mouse brain, meta-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA, Zolpidem, and endogenous neurosteroid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-13 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G4O
| Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with didesethylflurazepam and endogenous GABA | Descriptor: | (5M)-1-(2-aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Sun, C, Gouaux, E. | Deposit date: | 2023-02-10 | Release date: | 2023-09-20 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature, 622, 2023
|
|
8G6C
| |
8GAR
| |
8GBO
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, LEU-AIB-ALA-AIB-LEU-CYS-GLN-AIB-LEU, NICOTINIC ACID | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-26 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GBA
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, LEU-(AIB)-ALA-SER-LEU-ALA-CYS-(AIB)-LEU, NICOTINIC ACID | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-24 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GBM
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, ACETATE ION, LEAD (II) ION, ... | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-26 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GD6
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, NICOTINIC ACID, NIO-LEU-AIB-ALA-AIB-LEU-AIB-CYS-AIB-LEU-BPH | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-03-03 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.91 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GBI
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, ACETONITRILE, LEU-(AIB)-ALA-CYS-LEU-CYS-CYS-(AIB)-LEU, ... | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-26 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GBH
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, LEU-(AIB)-ALA-SER-LEU-ALA-(OCS)-(AIB)-LEU, NICOTINIC ACID | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-26 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.02 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GB9
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, LEAD (II) ION, LEU-AIB-ALA-SER-LEU-ALA-CYS-AIB-LEU, ... | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-02-24 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
8GIV
| |
8GD8
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | Descriptor: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, NICOTINIC ACID, NIO-LEU-AIB-ALA-CYS-LEU-AIB-GLN-AIB-LEU-BPH | Authors: | Hess, S.S, Nguyen, A.I. | Deposit date: | 2023-03-03 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
|
|
7ZPQ
| Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | Deposit date: | 2022-04-28 | Release date: | 2023-02-22 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
|
|
7OIT
| Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) | Descriptor: | AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-12 | Release date: | 2022-06-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
|
|
7OG1
| AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-05 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
|
|
7OHI
| FCHO1-peptide-AP2 alpha ear complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ... | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
|
|
7OHZ
| Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged) | Descriptor: | AP-2 complex subunit mu,F-BAR domain only protein 2 | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | Deposit date: | 2021-05-11 | Release date: | 2022-06-01 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
|
|