1K99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k99 by Molmil](/molmil-images/mine/1k99) | |
6M7P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7p by Molmil](/molmil-images/mine/6m7p) | Human DNA polymerase eta extension complex with cdA at the -2 position | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*TP*GP*TP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*CP*(02I)P*CP*AP*CP*AP*CP*T)-3'), ... | Authors: | Gregory, M.T, Yang, W. | Deposit date: | 2018-08-20 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
4XVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xvm by Molmil](/molmil-images/mine/4xvm) | |
4XVI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xvi by Molmil](/molmil-images/mine/4xvi) | |
6M7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7t by Molmil](/molmil-images/mine/6m7t) | Human DNA polymerase eta in a non-productive ternary complex with Ca2+ and dTTP oppositing cdA | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... | Authors: | Weng, P, Gao, Y, Yang, W. | Deposit date: | 2018-08-21 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6M7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m7u by Molmil](/molmil-images/mine/6m7u) | Human DNA polymerase eta in a non-productive ternary complex with Mg2+ and dTMPNPP oppositing cdA | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... | Authors: | Weng, P, Gao, Y, Yang, W. | Deposit date: | 2018-08-21 | Release date: | 2018-09-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
4XVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xvk by Molmil](/molmil-images/mine/4xvk) | Binary complex of human polymerase nu and DNA with the finger domain closed | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... | Authors: | Lee, Y.-S, Yang, W. | Deposit date: | 2015-01-27 | Release date: | 2015-03-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
|
|
4XVL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xvl by Molmil](/molmil-images/mine/4xvl) | Binary complex of human polymerase nu and DNA with the finger domain open | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... | Authors: | Lee, Y.-S, Yang, W. | Deposit date: | 2015-01-27 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
|
|
6N7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7w by Molmil](/molmil-images/mine/6n7w) | Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes) | Descriptor: | DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-11-28 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9v by Molmil](/molmil-images/mine/6n9v) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7i by Molmil](/molmil-images/mine/6n7i) | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA) | Descriptor: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-27 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9u by Molmil](/molmil-images/mine/6n9u) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1) | Descriptor: | DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
8EBS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebs by Molmil](/molmil-images/mine/8ebs) | |
8EBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebu by Molmil](/molmil-images/mine/8ebu) | XPC release from Core7-XPA-DNA (Cy5) | Descriptor: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | Authors: | Kim, J, Yang, W. | Deposit date: | 2022-08-31 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
|
|
8EBT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebt by Molmil](/molmil-images/mine/8ebt) | |
8EBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eby by Molmil](/molmil-images/mine/8eby) | XPC release from Core7-XPA-DNA (AP) | Descriptor: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | Authors: | Kim, J, Yang, W. | Deposit date: | 2022-08-31 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
|
|
8EBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebv by Molmil](/molmil-images/mine/8ebv) | |
8EBW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebw by Molmil](/molmil-images/mine/8ebw) | |
8EBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ebx by Molmil](/molmil-images/mine/8ebx) | |
6C2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c2v by Molmil](/molmil-images/mine/6c2v) | Solution structure of a phosphate-loop protein | Descriptor: | phosphate-loop protein | Authors: | Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G. | Deposit date: | 2018-01-09 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Simple yet functional phosphate-loop proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6N9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9x by Molmil](/molmil-images/mine/6n9x) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6C2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c2u by Molmil](/molmil-images/mine/6c2u) | Solution structure of a phosphate-loop protein | Descriptor: | phosphate-loop protein | Authors: | Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G. | Deposit date: | 2018-01-09 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Simple yet functional phosphate-loop proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
1EWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ewr by Molmil](/molmil-images/mine/1ewr) | CRYSTAL STRUCTURE OF TAQ MUTS | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS | Authors: | Obmolova, G, Ban, C, Hsieh, P, Yang, W. | Deposit date: | 2000-04-26 | Release date: | 2000-10-23 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature, 407, 2000
|
|
6N7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7n by Molmil](/molmil-images/mine/6n7n) | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-11-27 | Release date: | 2019-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|
6N9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n9w by Molmil](/molmil-images/mine/6n9w) | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | Deposit date: | 2018-12-04 | Release date: | 2019-03-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures and operating principles of the replisome. Science, 363, 2019
|
|