6M7P

Human DNA polymerase eta extension complex with cdA at the -2 position

Summary for 6M7P

• Entry DOI: 10.2210/pdb6m7p/pdb
• Related: 6M7O
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*CP*(02I)P*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*GP*TP*G)-3'), ... (7 entities in total)
• Functional Keywords: translesion synthesis, cda, dna binding protein, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55310.60

Authors

Gregory, M.T.,Yang, W. (deposition date: 2018-08-20, release date: 2018-09-12, Last modification date: 2023-10-11)

• Primary citation: Weng, P.J.,Gao, Y.,Gregory, M.T.,Wang, P.,Wang, Y.,Yang, W.; Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.; Proc. Natl. Acad. Sci. U.S.A., 115:10660-10665, 2018; PubMed: 30275308; DOI: 10.1073/pnas.1812856115

Experimental method

X-RAY DIFFRACTION (1.75 Å)