6E2O
 
 | | ASK1 kinase domain complex with inhibitor | | Descriptor: | 4-(4-cyclopropyl-1H-imidazol-1-yl)-N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 5 | | Authors: | Lansdon, E.B. | | Deposit date: | 2018-07-11 | | Release date: | 2018-09-19 | | Last modified: | 2018-10-17 | | Method: | X-RAY DIFFRACTION (2.389 Å) | | Cite: | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
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5KUD
 | | Crystal structure of full length Cry6Aa | | Descriptor: | Pesticidal crystal protein Cry6Aa | | Authors: | Kelker, M.S, Xu, X, Lee, M, Chan, M, Hung, S, Dementiev, K, Chikwana, V.M, Hey, T, Narva, K. | | Deposit date: | 2016-07-13 | | Release date: | 2016-08-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins.
Bmc Biol., 14, 2016
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5KUC
 | | Crystal structure of trypsin activated Cry6Aa | | Descriptor: | Pesticidal crystal protein Cry6Aa | | Authors: | Kelker, M.S, Xu, X, Lee, M, Chan, M, Hung, S, Dementiev, K, Hey, T, Chikwana, V.M, Narva, K.E. | | Deposit date: | 2016-07-13 | | Release date: | 2016-08-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins.
Bmc Biol., 14, 2016
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8F7Z
 | | VRC34.01_mm28 bound to fusion peptide | | Descriptor: | HIV-1 Env Fusion Peptide, VRC34_m228 Light Chain, VRC34_mm28 Heavy Chain | | Authors: | Olia, A.S, Kwong, P.D. | | Deposit date: | 2022-11-21 | | Release date: | 2023-11-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.
Nat Commun, 14, 2023
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8G4M
 | | Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Wang, S, Morano, N.C, Shapiro, L, Kwong, P.D. | | Deposit date: | 2023-02-10 | | Release date: | 2023-07-12 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
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8G4T
 | | Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein BG505 DS-SOSIP gp120, ... | | Authors: | Wang, S, Kwong, P.D. | | Deposit date: | 2023-02-10 | | Release date: | 2023-07-12 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
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2JTN
 | | NMR Solution Structure of a ldb1-LID:Lhx3-LIM complex | | Descriptor: | LIM domain-binding protein 1, LIM/homeobox protein Lhx3, ZINC ION | | Authors: | Lee, C, Nancarrow, A.L, Mackay, J.P, Matthews, J.M. | | Deposit date: | 2007-08-03 | | Release date: | 2008-06-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Embo J., 27, 2008
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3ZG0
 | | Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and muramic acid at allosteric site obtained by cocrystallization | | Descriptor: | CADMIUM ION, CHLORIDE ION, Ceftaroline, ... | | Authors: | Otero, L.H, Rojas-Altuve, A, Hermoso, J.A. | | Deposit date: | 2012-12-13 | | Release date: | 2013-10-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZFZ
 | | Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and muramic acid at allosteric site obtained by soaking | | Descriptor: | CADMIUM ION, CHLORIDE ION, Ceftaroline, ... | | Authors: | Otero, L.H, Rojas-Altuve, A, Hermoso, J.A. | | Deposit date: | 2012-12-13 | | Release date: | 2013-10-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZG5
 | | Crystal structure of PBP2a from MRSA in complex with peptidoglycan analogue at allosteric | | Descriptor: | CADMIUM ION, CHLORIDE ION, PEPTIDOGLYCAN ANALOGUE, ... | | Authors: | Otero, L.H, Rojas-Altuve, A, Hermoso, J.A. | | Deposit date: | 2012-12-14 | | Release date: | 2013-10-09 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
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6JN0
 | | Structure of H247A mutant peptidoglycan peptidase complex with tetra-tri peptide | | Descriptor: | C0O-DAL-API, Peptidase M23, ZINC ION | | Authors: | Min, K.J, An, D.R, Yoon, H.J, Suh, S.W, Lee, H.H. | | Deposit date: | 2019-03-13 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.164 Å) | | Cite: | Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni.
Nat Commun, 11, 2020
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6JN7
 | | Structure of H216A mutant closed form peptidoglycan peptidase | | Descriptor: | D(-)-TARTARIC ACID, Peptidase M23, ZINC ION | | Authors: | Min, K.J, An, D.R, Yoon, H.J, Suh, S.W, Lee, H.H. | | Deposit date: | 2019-03-13 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni.
Nat Commun, 11, 2020
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6JMY
 | | Structure of wild type closed form of peptidoglycan peptidase | | Descriptor: | CITRIC ACID, Peptidase M23, ZINC ION | | Authors: | Min, K.J, An, D.R, Yoon, H.J, Suh, S.W, Lee, H.H. | | Deposit date: | 2019-03-13 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.661 Å) | | Cite: | Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni.
Nat Commun, 11, 2020
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6KBN
 | | Crystal structure of Vac8 (del 19-33) bound to Atg13 | | Descriptor: | Autophagy-related protein 13, Vacuolar protein 8 | | Authors: | Park, J, Lee, C. | | Deposit date: | 2019-06-25 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.
Autophagy, 16, 2020
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6I05
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6KV1
 | | Structure of wild type closed form of peptidoglycan peptidase ZN SAD | | Descriptor: | CITRIC ACID, Peptidase M23, ZINC ION | | Authors: | Min, K.J, An, D.R, Yoon, H.J, Suh, S.W, Lee, H.H. | | Deposit date: | 2019-09-03 | | Release date: | 2020-01-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.722 Å) | | Cite: | Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni.
Nat Commun, 11, 2020
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6I0N
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3TBL
 | | Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki Fragment Maturation | | Descriptor: | Proliferating cell nuclear antigen, Ubiquitin | | Authors: | Zhang, Z, Lee, M, Lee, E, Zhang, S. | | Deposit date: | 2011-08-07 | | Release date: | 2012-05-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.903 Å) | | Cite: | Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation.
Cell Cycle, 11, 2012
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6I09
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6I0A
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6KBM
 | | Crystal structure of Vac8 bound to Atg13 | | Descriptor: | Autophagy-related protein 13, Vacuolar protein 8 | | Authors: | Park, J, Lee, C. | | Deposit date: | 2019-06-25 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.902 Å) | | Cite: | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.
Autophagy, 16, 2020
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6GHZ
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6GI3
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8C0S
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8C0P
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