6R7E
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![BU of 6r7e by Molmil](/molmil-images/mine/6r7e) | N-terminally reversed variant of FimA E. coli with alanine insertion at position 20 | Descriptor: | FimA, SULFATE ION | Authors: | Zyla, D, Echeverria, B, Glockshuber, R. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
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6S09
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![BU of 6s09 by Molmil](/molmil-images/mine/6s09) | C-terminally extended and N-terminally truncated variant of FimA E. coli at 1.5 Angstrom resolution | Descriptor: | ACETIC ACID, FimA, SODIUM ION, ... | Authors: | Zyla, D, Echeverria, B, Glockshuber, R. | Deposit date: | 2019-06-14 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
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6R74
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![BU of 6r74 by Molmil](/molmil-images/mine/6r74) | N-terminally reversed variant of FimA E. coli | Descriptor: | SULFATE ION, Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Echeverria, B, Glockshuber, R. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
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7U9G
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![BU of 7u9g by Molmil](/molmil-images/mine/7u9g) | Rabies virus glycoprotein pre-fusion trimer in complex with neutralizing antibody RVA122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, RVA122 Fab Heavy Chain, ... | Authors: | Callaway, H.M, Zyla, D, Larrous, F, Dias de Melo, G, Hastie, K.M, Avalos, R.D, Agarwal, A, Bouhry, H, Corti, D, Saphire, E.O. | Deposit date: | 2022-03-10 | Release date: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Sci Adv, 8, 2022
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6YEV
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![BU of 6yev by Molmil](/molmil-images/mine/6yev) | |
6SYM
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![BU of 6sym by Molmil](/molmil-images/mine/6sym) | |
5LP9
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![BU of 5lp9 by Molmil](/molmil-images/mine/5lp9) | FimA wt from S. flexneri | Descriptor: | Major type 1 subunit fimbrin (Pilin) | Authors: | Zyla, D, Capitani, G, Prota, A, Glockshuber, R. | Deposit date: | 2016-08-12 | Release date: | 2017-12-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (0.88626635 Å) | Cite: | Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria. J.Biol.Chem., 2019
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8PTU
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![BU of 8ptu by Molmil](/molmil-images/mine/8ptu) | 2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-14 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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8UUP
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![BU of 8uup by Molmil](/molmil-images/mine/8uup) | Structure of the Measles virus Fusion protein in the pre-fusion conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | Authors: | Zyla, D, Saphire, E.O. | Deposit date: | 2023-11-01 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.11 Å) | Cite: | A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384, 2024
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8UT2
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![BU of 8ut2 by Molmil](/molmil-images/mine/8ut2) | Pre-fusion Measles virus fusion protein complexed with Fab 77 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zyla, D, Saphire, E.O. | Deposit date: | 2023-10-30 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384, 2024
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8UTF
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![BU of 8utf by Molmil](/molmil-images/mine/8utf) | |
8UUQ
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![BU of 8uuq by Molmil](/molmil-images/mine/8uuq) | |
9AT8
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![BU of 9at8 by Molmil](/molmil-images/mine/9at8) | Fab 77-stabilized MeV F ectodomain fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAB 77 heavy chain, ... | Authors: | Zyla, D, Saphire, E.O. | Deposit date: | 2024-02-26 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384, 2024
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5NKT
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![BU of 5nkt by Molmil](/molmil-images/mine/5nkt) | FimA wt from E. coli | Descriptor: | SULFATE ION, Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Capitani, G, Prota, A, Glockshuber, R. | Deposit date: | 2017-04-03 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria. J.Biol.Chem., 2019
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6Y7S
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![BU of 6y7s by Molmil](/molmil-images/mine/6y7s) | 2.85 A cryo-EM structure of the in vivo assembled type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Hospenthal, M, Waksman, G, Glockshuber, R. | Deposit date: | 2020-03-02 | Release date: | 2021-03-31 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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6X84
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![BU of 6x84 by Molmil](/molmil-images/mine/6x84) | |
8PSV
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![BU of 8psv by Molmil](/molmil-images/mine/8psv) | 2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-13 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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6ZS5
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![BU of 6zs5 by Molmil](/molmil-images/mine/6zs5) | 3.5 A cryo-EM structure of human uromodulin filament core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | Deposit date: | 2020-07-15 | Release date: | 2020-09-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism. Elife, 9, 2020
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6ZYA
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![BU of 6zya by Molmil](/molmil-images/mine/6zya) | Extended human uromodulin filament core at 3.5 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | Deposit date: | 2020-07-31 | Release date: | 2020-09-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism. Elife, 9, 2020
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8F0G
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![BU of 8f0g by Molmil](/molmil-images/mine/8f0g) | Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1C3 Fab Heavy Chain, ... | Authors: | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | Deposit date: | 2022-11-02 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence. Cell Rep, 42, 2023
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8F0H
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![BU of 8f0h by Molmil](/molmil-images/mine/8f0h) | Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 1H2 heavy chain, Antibody Fab 1H2 light chain, ... | Authors: | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | Deposit date: | 2022-11-02 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence. Cell Rep, 42, 2023
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7UOV
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![BU of 7uov by Molmil](/molmil-images/mine/7uov) | |
7UOT
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![BU of 7uot by Molmil](/molmil-images/mine/7uot) | Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 37.2D heavy chain (variable domain), ... | Authors: | Li, H, Saphire, E.O. | Deposit date: | 2022-04-13 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus. Sci Transl Med, 14, 2022
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5OH0
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![BU of 5oh0 by Molmil](/molmil-images/mine/5oh0) | The Cryo-Electron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Hospenthal, M.K, Costa, T.R.D, Redzej, A, Waksman, G. | Deposit date: | 2017-07-13 | Release date: | 2017-11-22 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod. Structure, 25, 2017
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