4XYJ
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![BU of 4xyj by Molmil](/molmil-images/mine/4xyj) | Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... | Authors: | Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-02-02 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
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4XYK
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![BU of 4xyk by Molmil](/molmil-images/mine/4xyk) | Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... | Authors: | Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-02-02 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
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7TFF
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![BU of 7tff by Molmil](/molmil-images/mine/7tff) | Crystal structure of human platelet phosphofructokinase-1 mutant- D564N | Descriptor: | ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ... | Authors: | Hansen, H, Webb, B.A, Robart, A.R, Narayanasami, S. | Deposit date: | 2022-01-06 | Release date: | 2023-07-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity. Biochem.J., 480, 2023
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7LUB
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![BU of 7lub by Molmil](/molmil-images/mine/7lub) | |
7LW1
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![BU of 7lw1 by Molmil](/molmil-images/mine/7lw1) | Human phosphofructokinase-1 liver type bound to activator NA-11 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Lynch, E.M, Kollman, J.M, Webb, B. | Deposit date: | 2021-02-27 | Release date: | 2022-01-26 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Selective activation of PFKL suppresses the phagocytic oxidative burst. Cell, 184, 2021
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7MBH
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![BU of 7mbh by Molmil](/molmil-images/mine/7mbh) | Structure of Human Enolase 2 in complex with phosphoserine | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Gamma-enolase, ... | Authors: | Leonard, P.G, Hicks, K.G, Rutter, J. | Deposit date: | 2021-03-31 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science, 379, 2023
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6D8V
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![BU of 6d8v by Molmil](/molmil-images/mine/6d8v) | Methyl-accepting Chemotaxis protein X | Descriptor: | 1,1-DIMETHYL-PROLINIUM, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Probable chemoreceptor (Methyl-accepting chemotaxis) transmembrane protein | Authors: | Shrestha, M, Schubot, F.D. | Deposit date: | 2018-04-27 | Release date: | 2019-04-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the sensory domain of McpX fromSinorhizobium meliloti, the first known bacterial chemotactic sensor for quaternary ammonium compounds. Biochem. J., 475, 2018
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