7LUB
Crystal structure of recombinant human fumarase in complex with D-2-amino-3-phosphono-propionic acid
Summary for 7LUB
Entry DOI | 10.2210/pdb7lub/pdb |
Descriptor | Fumarate hydratase, mitochondrial, D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | fumarase, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 100893.22 |
Authors | Cardoso, I.A.,Nonato, M.C. (deposition date: 2021-02-21, release date: 2022-02-23, Last modification date: 2023-10-25) |
Primary citation | Hicks, K.G.,Cluntun, A.A.,Schubert, H.L.,Hackett, S.R.,Berg, J.A.,Leonard, P.G.,Ajalla Aleixo, M.A.,Zhou, Y.,Bott, A.J.,Salvatore, S.R.,Chang, F.,Blevins, A.,Barta, P.,Tilley, S.,Leifer, A.,Guzman, A.,Arok, A.,Fogarty, S.,Winter, J.M.,Ahn, H.C.,Allen, K.N.,Block, S.,Cardoso, I.A.,Ding, J.,Dreveny, I.,Gasper, W.C.,Ho, Q.,Matsuura, A.,Palladino, M.J.,Prajapati, S.,Sun, P.,Tittmann, K.,Tolan, D.R.,Unterlass, J.,VanDemark, A.P.,Vander Heiden, M.G.,Webb, B.A.,Yun, C.H.,Zhao, P.,Wang, B.,Schopfer, F.J.,Hill, C.P.,Nonato, M.C.,Muller, F.L.,Cox, J.E.,Rutter, J. Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science, 379:996-1003, 2023 Cited by PubMed: 36893255DOI: 10.1126/science.abm3452 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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