7PIM
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![BU of 7pim by Molmil](/molmil-images/mine/7pim) | Partial structure of tyrosine hydroxylase lacking the first 35 residues in complex with dopamine. | Descriptor: | FE (III) ION, L-DOPAMINE, Regulatory domain alpha-helix, ... | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2021-08-20 | Release date: | 2021-12-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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2XQL
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![BU of 2xql by Molmil](/molmil-images/mine/2xql) | Fitting of the H2A-H2B histones in the electron microscopy map of the complex Nucleoplasmin:H2A-H2B histones (1:5). | Descriptor: | HISTONE H2A-IV, HISTONE H2B 5 | Authors: | Ramos, I, Martin-Benito, J, Finn, R, Bretana, L, Aloria, K, Arizmendi, J.M, Ausio, J, Muga, A, Valpuesta, J.M, Prado, A. | Deposit date: | 2010-09-02 | Release date: | 2010-11-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (19.5 Å) | Cite: | Nucleoplasmin Binds Histone H2A-H2B Dimers Through its Distal Face. J.Biol.Chem., 285, 2010
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2WFS
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![BU of 2wfs by Molmil](/molmil-images/mine/2wfs) | Fitting of influenza virus NP structure into the 9-fold symmetryzed cryoEM reconstruction of an active RNP particle. | Descriptor: | NUCLEOPROTEIN | Authors: | Coloma, R, Valpuesta, J.M, Arranz, R, Carrascosa, J.L, Ortin, J, Martin-Benito, J. | Deposit date: | 2009-04-15 | Release date: | 2009-07-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | The Structure of a Biologically Active Influenza Virus Ribonucleoprotein Complex. Plos Pathog., 5, 2009
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1H5W
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![BU of 1h5w by Molmil](/molmil-images/mine/1h5w) | 2.1A Bacteriophage Phi-29 Connector | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, UPPER COLLAR PROTEIN | Authors: | Guasch, A, Pous, J, Ibarra, B, Gomis-Ruth, F.X, Valpuesta, J.M, Sousa, N, Carrascosa, J.L, Coll, M. | Deposit date: | 2001-05-28 | Release date: | 2002-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Detailed Architecture of a DNA Translocating Machine: The High-Resolution Structure of the Bacteriophage Phi29 Connector Particle. J.Mol.Biol., 315, 2002
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6ZVP
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![BU of 6zvp by Molmil](/molmil-images/mine/6zvp) | Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms | Descriptor: | FE (III) ION, L-DOPAMINE, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-07-27 | Release date: | 2021-11-17 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZZU
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![BU of 6zzu by Molmil](/molmil-images/mine/6zzu) | Partial structure of the substrate-free tyrosine hydroxylase (apo-TH). | Descriptor: | FE (III) ION, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-08-05 | Release date: | 2021-11-17 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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7A2G
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![BU of 7a2g by Molmil](/molmil-images/mine/7a2g) | Full-length structure of the substrate-free tyrosine hydroxylase (apo-TH). | Descriptor: | FE (III) ION, Tyrosine 3-monooxygenase | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Flydal, M.I, Martinez, A, Valpuesta, J.M. | Deposit date: | 2020-08-17 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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6ZN2
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![BU of 6zn2 by Molmil](/molmil-images/mine/6zn2) | Partial structure of tyrosine hydroxylase in complex with dopamine showing the catalytic domain and an alpha-helix from the regulatory domain involved in dopamine binding. | Descriptor: | FE (III) ION, L-DOPAMINE, SER-LEU-ILE-GLU-ASP-ALA-ARG-LYS-GLU-ARG-GLU-ALA-ALA-VAL-ALA-ALA-ALA-ALA, ... | Authors: | Bueno-Carrasco, M.T, Cuellar, J, Santiago, C, Valpuesta, J.M, Martinez, A, Flydal, M.I. | Deposit date: | 2020-07-06 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation. Nat Commun, 13, 2022
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3IZG
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![BU of 3izg by Molmil](/molmil-images/mine/3izg) | Bacteriophage T7 prohead shell EM-derived atomic model | Descriptor: | Major capsid protein 10A | Authors: | Ionel, A, Velazquez-Muriel, J.A, Agirrezabala, X, Luque, D, Cuervo, A, Caston, J.R, Valpuesta, J.M, Martin-Benito, J, Carrascosa, J.L. | Deposit date: | 2010-10-27 | Release date: | 2010-11-17 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10.9 Å) | Cite: | Molecular rearrangements involved in the capsid shell maturation of bacteriophage T7. J.Biol.Chem., 286, 2011
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6QB8
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![BU of 6qb8 by Molmil](/molmil-images/mine/6qb8) | Human CCT:mLST8 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Cuellar, J, Santiago, C, Ludlam, W.G, Bueno-Carrasco, M.T, Valpuesta, J.M, Willardson, B.M. | Deposit date: | 2018-12-20 | Release date: | 2019-07-03 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly. Nat Commun, 10, 2019
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2XSM
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![BU of 2xsm by Molmil](/molmil-images/mine/2xsm) | Crystal structure of the mammalian cytosolic chaperonin CCT in complex with tubulin | Descriptor: | CCT | Authors: | Munoz, I.G, Yebenes, H, Zhou, M, Mesa, P, Serna, M, Bragado-Nilsson, E, Beloso, A, Robinson, C.V, Valpuesta, J.M, Montoya, G. | Deposit date: | 2010-10-29 | Release date: | 2010-12-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin. Nat.Struct.Mol.Biol., 18, 2011
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2XVR
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![BU of 2xvr by Molmil](/molmil-images/mine/2xvr) | Phage T7 empty mature head shell | Descriptor: | MAJOR CAPSID PROTEIN 10A | Authors: | Ionel, A, Velazquez-Muriel, J.A, Luque, D, Cuervo, A, Caston, J.R, Valpuesta, J.M, Martin-Benito, J, Carrascosa, J.L. | Deposit date: | 2010-10-28 | Release date: | 2010-12-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | Molecular Rearrangements Involved in the Capsid Shell Maturation of Bacteriophage T7. J.Biol.Chem., 286, 2011
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3J4A
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![BU of 3j4a by Molmil](/molmil-images/mine/3j4a) | Structure of gp8 connector protein | Descriptor: | Head-to-tail joining protein | Authors: | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | Deposit date: | 2013-07-09 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structural characterization of the bacteriophage t7 tail machinery. J.Biol.Chem., 288, 2013
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3J4B
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![BU of 3j4b by Molmil](/molmil-images/mine/3j4b) | Structure of T7 gatekeeper protein (gp11) | Descriptor: | Tail tubular protein A | Authors: | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | Deposit date: | 2013-07-09 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structural characterization of the bacteriophage t7 tail machinery. J.Biol.Chem., 288, 2013
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4BBL
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![BU of 4bbl by Molmil](/molmil-images/mine/4bbl) | Cryo-electron microscopy reconstruction of the helical part of influenza A virus ribonucleoprotein isolated from virions. | Descriptor: | NUCLEOPROTEIN, RNA | Authors: | Arranz, R, Coloma, R, Chichon, F.J, Conesa, J.J, Carrascosa, J.L, Valpuesta, J.M, Ortin, J, Martin-Benito, J. | Deposit date: | 2012-09-26 | Release date: | 2012-12-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (18 Å) | Cite: | The Structure of Native Influenza Virion Ribonucleoproteins Science, 338, 2012
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4BIJ
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![BU of 4bij by Molmil](/molmil-images/mine/4bij) | Threading model of T7 large terminase | Descriptor: | DNA MATURASE B | Authors: | Dauden, M.I, Martin-Benito, J, Sanchez-Ferrero, J.C, Pulido-Cid, M, Valpuesta, J.M, Carrascosa, J.L. | Deposit date: | 2013-04-10 | Release date: | 2013-05-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | Large Terminase Conformational Change Induced by Connector Binding in Bacteriophage T7 J.Biol.Chem., 288, 2013
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4BIL
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![BU of 4bil by Molmil](/molmil-images/mine/4bil) | Threading model of the T7 large terminase within the gp8gp19 complex | Descriptor: | DNA MATURASE B | Authors: | Dauden, M.I, Martin-Benito, J, Sanchez-Ferrero, J.C, Pulido-Cid, M, Valpuesta, J.M, Carrascosa, J.L. | Deposit date: | 2013-04-10 | Release date: | 2013-05-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (29 Å) | Cite: | Large Terminase Conformational Change Induced by Connector Binding in Bacteriophage T7 J.Biol.Chem., 288, 2013
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7ZHS
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![BU of 7zhs by Molmil](/molmil-images/mine/7zhs) | 3D reconstruction of the cylindrical assembly of DnaJA2 delta G/F by imposing D5 symmetry | Descriptor: | Ubiquitin-like protein SMT3,DnaJ homolog subfamily A member 2, ZINC ION | Authors: | Cuellar, J, Velasco-Carneros, L, Santiago, C, Martin-Benito, J, Valpuesta, J, Muga, A. | Deposit date: | 2022-04-07 | Release date: | 2023-07-26 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70. Nat Commun, 14, 2023
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2EU1
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![BU of 2eu1 by Molmil](/molmil-images/mine/2eu1) | Crystal structure of the chaperonin GroEL-E461K | Descriptor: | GROEL | Authors: | Cabo-Bilbao, A, Spinelli, S, Sot, B, Agirre, J, Mechaly, A.E, Muga, A, Guerin, D.M.A. | Deposit date: | 2005-10-28 | Release date: | 2006-08-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroEL(E461K). J.Struct.Biol., 155, 2006
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6QIY
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![BU of 6qiy by Molmil](/molmil-images/mine/6qiy) | CI-2, conformation 1 | Descriptor: | Subtilisin-chymotrypsin inhibitor-2A | Authors: | Romero, A, Ruiz, F.M. | Deposit date: | 2019-01-21 | Release date: | 2019-12-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Engineering protein assemblies with allosteric control via monomer fold-switching. Nat Commun, 10, 2019
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6QIZ
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![BU of 6qiz by Molmil](/molmil-images/mine/6qiz) | CI-2, conformation 2 | Descriptor: | Subtilisin-chymotrypsin inhibitor-2A | Authors: | Romero, A, Ruiz, F.M. | Deposit date: | 2019-01-21 | Release date: | 2019-12-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Engineering protein assemblies with allosteric control via monomer fold-switching. Nat Commun, 10, 2019
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3C7N
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![BU of 3c7n by Molmil](/molmil-images/mine/3c7n) | Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ... | Authors: | Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R. | Deposit date: | 2008-02-07 | Release date: | 2008-05-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.115 Å) | Cite: | Structure of the Hsp110:Hsc70 nucleotide exchange machine Mol.Cell, 31, 2008
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6YTU
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![BU of 6ytu by Molmil](/molmil-images/mine/6ytu) | Atomic-resolution structure of the coiled-coil dimerisation domain of human Arc | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Activity-regulated cytoskeleton-associated protein, CHLORIDE ION | Authors: | Hallin, E.I, Touma, C, Bramham, C.R, Kursula, P. | Deposit date: | 2020-04-24 | Release date: | 2021-03-03 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif. Febs J., 288, 2021
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6YT5
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![BU of 6yt5 by Molmil](/molmil-images/mine/6yt5) | Cryo-EM structure of T7 bacteriophage DNA translocation gp15-gp16 core complex intermediate assembly | Descriptor: | Internal virion protein gp15, Peptidoglycan transglycosylase gp16 | Authors: | Perez-Ruiz, M, Pulido-Cid, M, Luque-Ortega, J.R, Cuervo, A, Carrascosa, J.L. | Deposit date: | 2020-04-23 | Release date: | 2021-09-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Assisted assembly of bacteriophage T7 core components for genome translocation across the bacterial envelope. Proc.Natl.Acad.Sci.USA, 118, 2021
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6YSZ
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![BU of 6ysz by Molmil](/molmil-images/mine/6ysz) | Cryo-EM structure of T7 bacteriophage DNA translocation gp15 core protein intermediate assembly | Descriptor: | Internal virion protein gp15 | Authors: | Perez-Ruiz, M, Pulido-Cid, M, Luque-Ortega, J.R, Cuervo, A, Carrascosa, J.L. | Deposit date: | 2020-04-23 | Release date: | 2021-09-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Assisted assembly of bacteriophage T7 core components for genome translocation across the bacterial envelope. Proc.Natl.Acad.Sci.USA, 118, 2021
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