6YTU

Atomic-resolution structure of the coiled-coil dimerisation domain of human Arc

Summary for 6YTU

• Entry DOI: 10.2210/pdb6ytu/pdb
• Descriptor: Activity-regulated cytoskeleton-associated protein, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: arc, oligomerisation, coiled coil, dimer, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 9205.96

Authors

Hallin, E.I.,Touma, C.,Bramham, C.R.,Kursula, P. (deposition date: 2020-04-24, release date: 2021-03-03, Last modification date: 2021-05-12)

• Primary citation: Eriksen, M.S.,Nikolaienko, O.,Hallin, E.I.,Grodem, S.,Bustad, H.J.,Flydal, M.I.,Merski, I.,Hosokawa, T.,Lascu, D.,Akerkar, S.,Cuellar, J.,Chambers, J.J.,O'Connell, R.,Muruganandam, G.,Loris, R.,Touma, C.,Kanhema, T.,Hayashi, Y.,Stratton, M.M.,Valpuesta, J.M.,Kursula, P.,Martinez, A.,Bramham, C.R.; Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif.; Febs J., 288:2930-2955, 2021; PubMed: 33175445; DOI: 10.1111/febs.15618

Experimental method

X-RAY DIFFRACTION (0.95 Å)