1IC4
| CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | Deposit date: | 2001-03-30 | Release date: | 2001-07-18 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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1IC7
| CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | Deposit date: | 2001-03-30 | Release date: | 2001-07-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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1IC5
| CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX | Descriptor: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | Authors: | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | Deposit date: | 2001-03-30 | Release date: | 2001-07-18 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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1UFU
| Crystal structure of ligand binding domain of immunoglobulin-like transcript 2 (ILT2; LIR-1) | Descriptor: | Immunoglobulin-like transcript 2 | Authors: | Shiroishi, M, Amano, K, Rasubala, L, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K. | Deposit date: | 2003-06-10 | Release date: | 2004-08-10 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Kinetic and thermodynamic properties of the interaction between Immunoglobulin like transcript (ILT) and MHC class I To be Published
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1VDG
| Crystal structure of LIR1.01, one of the alleles of LIR1 | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 1 | Authors: | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | Deposit date: | 2004-03-22 | Release date: | 2005-08-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of LIR1.03, one of the alleles of LIR1 To be Published
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5XMH
| Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, ... | Authors: | Shiroishi, M, Shimokawa, K, Lee, J.M, Kusakabe, M, Ueda, T. | Deposit date: | 2017-05-15 | Release date: | 2018-03-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity. J. Biol. Chem., 293, 2018
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2D3V
| Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11) | Descriptor: | leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1 | Authors: | Shiroishi, M, Kajikawa, M, Kuroki, K, Ose, T, Kohda, D, Maenaka, K. | Deposit date: | 2005-10-03 | Release date: | 2006-06-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the human monocyte-activating receptor, J.Biol.Chem., 281, 2006
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2DYP
| Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G | Descriptor: | 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K. | Deposit date: | 2006-09-15 | Release date: | 2006-11-07 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d) Proc.Natl.Acad.Sci.Usa, 103, 2006
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2D31
| Crystal structure of disulfide-linked HLA-G dimer | Descriptor: | 9-mer peptide from Histone H2A, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shiroishi, M, Kuroki, K, Ose, T, Rasubala, L, Shiratori, I, Arase, H, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K. | Deposit date: | 2005-09-23 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer J.Biol.Chem., 281, 2006
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2DQI
| Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-26 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQG
| Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQF
| Crystal structure of hyhel-10 FV mutant (y33ay53a) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQC
| Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQD
| Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQH
| Crystal structure of hyhel-10 FV mutant (Hy58a) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-26 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQE
| Crystal structure of hyhel-10 FV mutant (Hy53a) complexed with hen egg lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-25 | Release date: | 2007-01-23 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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2DQJ
| Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Shiroishi, M, Kondo, H, Tsumoto, K, Kumagai, I. | Deposit date: | 2006-05-26 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HEL J.Biol.Chem., 282, 2007
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1C08
| CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME ANTIBODY (HYHEL-10), LYSOZYME | Authors: | Shiroishi, M, Kondo, H, Matsushima, M, Tsumoto, K, Kumagai, I. | Deposit date: | 1999-07-15 | Release date: | 2000-07-19 | Last modified: | 2023-05-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces. J.Biol.Chem., 274, 1999
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1UGN
| Crystal structure of LIR1.02, one of the alleles of LIR1 | Descriptor: | Leukocyte immunoglobulin-like receptor 1 | Authors: | Shiroishi, M, Rasubala, L, Kuroki, K, Amano, K, Tsuchiya, N, Tokunaga, K, Kohda, D, Maenaka, K. | Deposit date: | 2003-06-17 | Release date: | 2004-08-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis. Hum.Mol.Genet., 14, 2005
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5Y25
| EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062 | Descriptor: | (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor | Authors: | Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A. | Deposit date: | 2017-07-24 | Release date: | 2018-07-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nat.Chem.Biol., 15, 2019
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6K60
| Structural and functional basis for HLA-G isoform recognition of immune checkpoint receptor LILRBs | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain G, ... | Authors: | Kuroki, K, Matsubara, H, Kanda, R, Miyashita, N, Shiroishi, M, Fukunaga, Y, Kamishikiryo, J, Fukunaga, A, Hirose, K, Sugita, Y, Kita, S, Ose, T, Maenaka, K. | Deposit date: | 2019-05-31 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.149 Å) | Cite: | Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms. J Immunol., 203, 2019
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1J05
| The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment | Descriptor: | GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ... | Authors: | Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I. | Deposit date: | 2002-11-01 | Release date: | 2003-12-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment To be Published
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1J1O
| Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | Deposit date: | 2002-12-13 | Release date: | 2003-01-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
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1J1X
| Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme | Descriptor: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | Authors: | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | Deposit date: | 2002-12-20 | Release date: | 2003-01-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
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3RZE
| Structure of the human histamine H1 receptor in complex with doxepin | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, (3Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ... | Authors: | Shimamura, T, Han, G.W, Shiroishi, M, Weyand, S, Tsujimoto, H, Winter, G, Katritch, V, Abagyan, R, Cherezov, V, Liu, W, Kobayashi, T, Stevens, R, Iwata, S, GPCR Network (GPCR) | Deposit date: | 2011-05-11 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the human histamine H1 receptor complex with doxepin. Nature, 475, 2011
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