4ZTO
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4ZTP
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4YWG
| Crystal structure of 830A in complex with V1V2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of anti-HIV-1 gp120 V1V2 antibody 830A, Light chain of anti-HIV-1 gp120 V1V2 antibody 830A, ... | Authors: | Pan, R, Kong, X. | Deposit date: | 2015-03-20 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel. J.Virol., 89, 2015
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5V6M
| Crystal Structure of Rabbit Anti-HIV-1 gp120 V3 Fab 10A3 in complex with V3 peptide ConB | Descriptor: | CALCIUM ION, Envelope glycoprotein gp120 V3 peptide of Con B sequence, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A3, ... | Authors: | Pan, R, Kong, X.-P. | Deposit date: | 2017-03-17 | Release date: | 2018-01-17 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120. J. Virol., 2018
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5V6L
| Crystal Structure of Rabbit Anti-HIV-1 gp120 V3 Fab 10A37 in complex with V3 peptide JR-FL | Descriptor: | Envelope glycoprotein, v3 region, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A37, ... | Authors: | Pan, R, Kong, X.-P. | Deposit date: | 2017-03-17 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.549 Å) | Cite: | Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120. J. Virol., 2018
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4XML
| Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424 | Descriptor: | Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424 | Authors: | Pan, R, Kong, X.-P. | Deposit date: | 2015-01-14 | Release date: | 2015-07-08 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL. J.Virol., 89, 2015
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6VU2
| M1214_N1 Fab structure | Descriptor: | M1214 N1 Fab heavy chain, M1214 N1 Fab light chain | Authors: | Pan, R, Kong, X. | Deposit date: | 2020-02-14 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA. Cell Host Microbe, 27, 2020
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5UBZ
| Fab structure of HIV gp120 specific mAb 1E12 | Descriptor: | Anti-HIV1 gp120 mAb 1E12 Fab heavy chain, Anti-HIV1 gp120 mAb 1E12 Fab light chain | Authors: | Pan, R, Kong, X.-P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies To be published
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5UBY
| Fab structure of anti-HIV-1 gp120 mAb 1A8 | Descriptor: | Heavy chain of Fab fragment of anti-HIV1 gp120 mAb 1A8, Light chain of Fab fragment of anti-HIV1 gp120 mAb 1A8 | Authors: | Pan, R, Kong, X.-P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies To be Published
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4XMK
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6CEZ
| Crystal Structure of Rabbit Anti-HIV-1 gp120 V2 Fab 16C2 in complex with V2 peptide ConB | Descriptor: | HIV-1 gp120 V2 Peptide Con B, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, Light chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2 | Authors: | Kong, X, Pan, R. | Deposit date: | 2018-02-13 | Release date: | 2018-09-12 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha 4 beta 7. PLoS Pathog., 14, 2018
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6W73
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4JO4
| Crystal structure of rabbit mAb R20 Fab | Descriptor: | PENTAETHYLENE GLYCOL, SULFATE ION, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ... | Authors: | Pan, R.M, Kong, X.P. | Deposit date: | 2013-03-16 | Release date: | 2013-07-31 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans. J.Virol., 87, 2013
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4JO3
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4JO1
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4JO2
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4F58
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4F57
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6DB7
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6DB6
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6DB5
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8H7Z
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8H7L
| Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7535 fab heavt chain, ... | Authors: | Liu, Z, Yan, A, Gao, Y. | Deposit date: | 2022-10-20 | Release date: | 2023-08-30 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants. Nat Commun, 15, 2024
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4D9L
| Fab structure of anti-HIV-1 gp120 V2 mAb 697 | Descriptor: | Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697 | Authors: | Pan, R.M, Kong, X.P. | Deposit date: | 2012-01-11 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.485 Å) | Cite: | Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology, 427, 2012
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6VY2
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