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5VNW
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BU of 5vnw by Molmil
Crystal structure of Nb.b201 bound to human serum albumin
Descriptor: GLYCEROL, LAURIC ACID, Nb.b201, ...
Authors:McMahon, C, Kruse, A.C.
Deposit date:2017-05-01
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Yeast surface display platform for rapid discovery of conformationally selective nanobodies.
Nat. Struct. Mol. Biol., 25, 2018
4H5J
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BU of 4h5j by Molmil
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P64 form)
Descriptor: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2012-09-18
Release date:2012-11-07
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012
4H5I
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BU of 4h5i by Molmil
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P1 form)
Descriptor: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2012-09-18
Release date:2012-11-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012
4L9O
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BU of 4l9o by Molmil
Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:McMahon, C, Jeffrey, P.D, Hughson, F.M.
Deposit date:2013-06-18
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Sec16 influences transitional ER sites by regulating rather than organizing COPII.
Mol Biol Cell, 24, 2013
5VNV
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BU of 5vnv by Molmil
Crystal structure of Nb.b201
Descriptor: FORMIC ACID, Nb.b201, PENTAETHYLENE GLYCOL, ...
Authors:Kruse, A.C, McMahon, C.
Deposit date:2017-05-01
Release date:2018-02-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Yeast surface display platform for rapid discovery of conformationally selective nanobodies.
Nat. Struct. Mol. Biol., 25, 2018
6DO1
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BU of 6do1 by Molmil
Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-like peptide S1I8, ...
Authors:Wingler, L.M, McMahon, C, Staus, D.P, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2018-06-08
Release date:2019-01-30
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.
Cell, 176, 2019
6OS1
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BU of 6os1 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Nanobody Nb.AT110i1_le, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
6OS2
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BU of 6os2 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
6OS0
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BU of 6os0 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, CHLORIDE ION, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
6WC3
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BU of 6wc3 by Molmil
Crystal structure of the SNARE Sec20 bound to Dsl1 complex subunit Tip20
Descriptor: Protein transport protein SEC20, Protein transport protein TIP20
Authors:Travis, S.M, Jeffrey, P.D, Hughson, F.M.
Deposit date:2020-03-29
Release date:2020-05-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.
J.Biol.Chem., 295, 2020
8TH4
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BU of 8th4 by Molmil
Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
Descriptor: AT118-L Nanobody, BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, ...
Authors:Skiba, M.A, Kruse, A.C.
Deposit date:2023-07-13
Release date:2024-05-22
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Antibodies expand the scope of angiotensin receptor pharmacology.
Nat.Chem.Biol., 2024
8TH3
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BU of 8th3 by Molmil
Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor
Descriptor: AT118-H nanobody, Type-1 angiotensin II receptor, Soluble cytochrome b562 complex, ...
Authors:Skiba, M.A, Kruse, A.C.
Deposit date:2023-07-13
Release date:2024-05-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Antibodies expand the scope of angiotensin receptor pharmacology.
Nat.Chem.Biol., 2024
8FTU
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BU of 8ftu by Molmil
Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure
Descriptor: Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1
Authors:Travis, S.M, Jeffrey, P.D, Hughson, F.M.
Deposit date:2023-01-13
Release date:2023-03-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (5.73 Å)
Cite:Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024

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数据于2024-11-06公开中

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