1CHC
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1HFH
| SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE | Descriptor: | FACTOR H, 15TH AND 16TH C-MODULE PAIR | Authors: | Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D. | Deposit date: | 1993-02-23 | Release date: | 1993-07-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of a pair of complement modules by nuclear magnetic resonance. J.Mol.Biol., 232, 1993
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1HFI
| SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE | Descriptor: | FACTOR H, 15TH C-MODULE PAIR | Authors: | Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D. | Deposit date: | 1993-02-23 | Release date: | 1993-07-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of a pair of complement modules by nuclear magnetic resonance. J.Mol.Biol., 232, 1993
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1VVC
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1VVD
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3OXU
| Complement components factor H CCP19-20 and C3d in complex | Descriptor: | Complement C3, GLYCEROL, HF protein | Authors: | Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. | Deposit date: | 2010-09-22 | Release date: | 2011-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for engagement by complement factor H of C3b on a self surface. Nat.Struct.Mol.Biol., 18, 2011
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4B2S
| Solution structure of CCP modules 11-12 of complement factor H | Descriptor: | COMPLEMENT FACTOR H | Authors: | Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | Deposit date: | 2012-07-17 | Release date: | 2012-10-17 | Last modified: | 2013-05-08 | Method: | SOLUTION NMR | Cite: | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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2BZM
| Solution structure of the primary host recognition region of complement factor H | Descriptor: | COMPLEMENT FACTOR H | Authors: | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | Deposit date: | 2005-08-18 | Release date: | 2006-03-22 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure. J.Biol.Chem., 281, 2006
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2WCY
| NMR solution structure of factor I-like modules of complement C7. | Descriptor: | COMPLEMENT COMPONENT C7 | Authors: | Phelan, M.M, Thai, C.T, Soares, D.C, Ogata, R.T, Barlow, P.N, Bramham, J. | Deposit date: | 2009-03-17 | Release date: | 2009-05-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement. J.Biol.Chem., 284, 2009
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1DV9
| STRUCTURAL CHANGES ACCOMPANYING PH-INDUCED DISSOCIATION OF THE B-LACTOGLOBULIN DIMER | Descriptor: | BETA-LACTOGLOBULIN | Authors: | Uhrinova, S, Smith, M.H, Jameson, G.B, Uhrin, D, Sawyer, L, Barlow, P.N. | Deposit date: | 2000-01-20 | Release date: | 2000-02-09 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structural changes accompanying pH-induced dissociation of the beta-lactoglobulin dimer. Biochemistry, 39, 2000
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2MCZ
| CR1 Sushi domains 1 and 2 | Descriptor: | Complement receptor type 1 | Authors: | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | Deposit date: | 2013-08-27 | Release date: | 2013-11-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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3SW0
| Structure of the C-terminal region (modules 18-20) of complement regulator Factor H | Descriptor: | Complement factor H, GLYCEROL, PHOSPHATE ION | Authors: | Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P. | Deposit date: | 2011-07-13 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH). Plos One, 7, 2012
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3R62
| Structure of complement regulator Factor H mutant, T1184R. | Descriptor: | Complement factor H, GLYCEROL | Authors: | Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P. | Deposit date: | 2011-03-21 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystallographic determination of the disease-associated T1184R variant of the complement Factor H. Acta Crystallogr.,Sect.D, 67, 2011
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2MCY
| CR1 Sushi domains 2 and 3 | Descriptor: | Complement receptor type 1 | Authors: | Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P. | Deposit date: | 2013-08-27 | Release date: | 2013-11-13 | Last modified: | 2014-01-22 | Method: | SOLUTION NMR | Cite: | Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor. J.Biol.Chem., 289, 2014
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2RLQ
| NMR structure of CCP modules 2-3 of complement factor H | Descriptor: | Complement factor H | Authors: | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | Deposit date: | 2007-07-29 | Release date: | 2008-02-19 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2RLP
| NMR structure of CCP modules 1-2 of complement factor H | Descriptor: | Complement factor H | Authors: | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | Deposit date: | 2007-07-28 | Release date: | 2008-02-19 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2JGX
| Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y) | Descriptor: | COMPLEMENT FACTOR H | Authors: | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | Deposit date: | 2007-02-16 | Release date: | 2007-03-20 | Last modified: | 2018-05-02 | Method: | SOLUTION NMR | Cite: | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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2V8E
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ... | Authors: | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | Deposit date: | 2007-08-07 | Release date: | 2007-10-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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2JGW
| Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H) | Descriptor: | COMPLEMENT FACTOR H | Authors: | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | Deposit date: | 2007-02-16 | Release date: | 2007-03-20 | Last modified: | 2018-05-02 | Method: | SOLUTION NMR | Cite: | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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2UWN
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | Authors: | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | Deposit date: | 2007-03-22 | Release date: | 2007-10-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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2KMS
| Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | Descriptor: | Complement factor H | Authors: | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | Deposit date: | 2009-08-04 | Release date: | 2009-11-03 | Last modified: | 2020-02-26 | Method: | SOLUTION NMR | Cite: | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module J.Mol.Biol., 395, 2010
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1GKN
| Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35) | Descriptor: | COMPLEMENT RECEPTOR TYPE 1 | Authors: | Smith, B.O, Mallin, R.L, Krych-Goldberg, M, Wang, X, Hauhart, R.E, Bromek, K, Uhrin, D, Atkinson, J.P, Barlow, P.N. | Deposit date: | 2001-08-16 | Release date: | 2002-04-18 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor Cell(Cambridge,Mass.), 108, 2002
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1H67
| NMR Structure of the CH Domain of Calponin | Descriptor: | CALPONIN ALPHA | Authors: | Bramham, J, Smith, B.O, Uhrin, D, Barlow, P.N, Winder, S.J. | Deposit date: | 2001-06-07 | Release date: | 2002-02-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Calponin Ch Domain and Fitting to the 3D-Helical Reconstruction of F-Actin:Calponin. Structure, 10, 2002
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1XWE
| NMR Structure of C345C (NTR) domain of C5 of complement | Descriptor: | Complement C5 | Authors: | Bramham, J, Thai, C.-T, Soares, D.C, Uhrin, D, Ogata, R.T, Barlow, P.N. | Deposit date: | 2004-10-30 | Release date: | 2004-12-21 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Functional Insights from the Structure of the Multifunctional C345C Domain of C5 of Complement J.Biol.Chem., 280, 2005
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1Z1M
| NMR structure of unliganded MDM2 | Descriptor: | Ubiquitin-protein ligase E3 Mdm2 | Authors: | Uhrinova, S, Uhrin, D, Powers, H, Watt, K, Zheleva, D, Fischer, P, McInnes, C, Barlow, P.N. | Deposit date: | 2005-03-04 | Release date: | 2005-06-28 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding J.Mol.Biol., 350, 2005
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