1Z1M

NMR structure of unliganded MDM2

Summary for 1Z1M

DescriptorUbiquitin-protein ligase E3 Mdm2 (1 entity in total)
Functional Keywordspeptide-binding groove, psudosymmetry, alpha-beta domains, ligase
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleoplasm Q00987
Total number of polymer chains1
Total molecular weight13571.59
Authors
Uhrinova, S.,Uhrin, D.,Powers, H.,Watt, K.,Zheleva, D.,Fischer, P.,McInnes, C.,Barlow, P.N. (deposition date: 2005-03-04, release date: 2005-06-28, Last modification date: 2011-07-13)
Primary citation
Uhrinova, S.,Uhrin, D.,Powers, H.,Watt, K.,Zheleva, D.,Fischer, P.,McInnes, C.,Barlow, P.N.
Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding
J.Mol.Biol., 350:587-598, 2005
PubMed: 15953616 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2005.05.010
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers377.3%13.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures