1Z1M

NMR structure of unliganded MDM2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	83
Details	Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	109
Details	Region: {"description":"Necessary for interaction with USP2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	100
Details	Region: {"description":"Sufficient to promote the mitochondrial pathway of apoptosis","evidences":[{"source":"PubMed","id":"30879903","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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