2PWY
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![BU of 2pwy by Molmil](/molmil-images/mine/2pwy) | Crystal Structure of a m1A58 tRNA methyltransferase | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, tRNA (adenine-N(1)-)-methyltransferase | Authors: | Barraud, P, Golinelli-Pimpaneau, B, Tisne, C. | Deposit date: | 2007-05-14 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Thermus thermophilus tRNA m(1)A(58) Methyltransferase and Biophysical Characterization of Its Interaction with tRNA. J.Mol.Biol., 377, 2008
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3CW5
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![BU of 3cw5 by Molmil](/molmil-images/mine/3cw5) | E. coli Initiator tRNA | Descriptor: | Initiator tRNA | Authors: | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | Deposit date: | 2008-04-21 | Release date: | 2008-09-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res., 36, 2008
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3CW6
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![BU of 3cw6 by Molmil](/molmil-images/mine/3cw6) | E. coli Initiator tRNA | Descriptor: | Initiator tRNA | Authors: | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | Deposit date: | 2008-04-21 | Release date: | 2008-09-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res., 36, 2008
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2LJH
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![BU of 2ljh by Molmil](/molmil-images/mine/2ljh) | |
2L6M
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![BU of 2l6m by Molmil](/molmil-images/mine/2l6m) | |
2MDR
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![BU of 2mdr by Molmil](/molmil-images/mine/2mdr) | Solution structure of the third double-stranded RNA-binding domain (dsRBD3) of human adenosine-deaminase ADAR1 | Descriptor: | Double-stranded RNA-specific adenosine deaminase | Authors: | Barraud, P, Banerjee, S, Mohamed, W.I, Jantsch, M.F, Allain, F.H. | Deposit date: | 2013-09-17 | Release date: | 2014-04-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. Proc.Natl.Acad.Sci.USA, 111, 2014
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2LYV
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![BU of 2lyv by Molmil](/molmil-images/mine/2lyv) | |
5MPG
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![BU of 5mpg by Molmil](/molmil-images/mine/5mpg) | |
5MPL
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![BU of 5mpl by Molmil](/molmil-images/mine/5mpl) | hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA | Descriptor: | Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU | Authors: | Barraud, P, Allain, F.H.-T. | Deposit date: | 2016-12-16 | Release date: | 2017-07-05 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7. Elife, 6, 2017
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6TNN
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![BU of 6tnn by Molmil](/molmil-images/mine/6tnn) | Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | Deposit date: | 2019-12-09 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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7ZLQ
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![BU of 7zlq by Molmil](/molmil-images/mine/7zlq) | |
7ZJ1
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![BU of 7zj1 by Molmil](/molmil-images/mine/7zj1) | Crystal structure of ADAR1-dsRBD3 dimer | Descriptor: | Double-stranded RNA-specific adenosine deaminase | Authors: | Mboukou, A, Barraud, P. | Deposit date: | 2022-04-08 | Release date: | 2023-10-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Dimerization of ADAR1 modulates site-specificity of RNA editing Biorxiv, 2023
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6QE6
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![BU of 6qe6 by Molmil](/molmil-images/mine/6qe6) | Structure of M. capricolum TrmK in complex with the natural cofactor product S-adenosyl-homocysteine (SAH) | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Adenine(22)-N(1))-methyltransferase | Authors: | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | Deposit date: | 2019-01-04 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6QE5
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![BU of 6qe5 by Molmil](/molmil-images/mine/6qe5) | Structure of E.coli RlmJ in complex with the natural cofactor product S-adenosyl-homocysteine (SAH) | Descriptor: | Ribosomal RNA large subunit methyltransferase J, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | Deposit date: | 2019-01-04 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6Q56
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![BU of 6q56 by Molmil](/molmil-images/mine/6q56) | Crystal structure of the B. subtilis M1A22 tRNA methyltransferase TrmK | Descriptor: | NICKEL (II) ION, tRNA (adenine(22)-N(1))-methyltransferase | Authors: | Degut, C, Roovers, M, Barraud, P, Brachet, F, Feller, A, Larue, V, Al Refaii, A, Caillet, J, Droogmans, L, Tisne, C. | Deposit date: | 2018-12-07 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition. Nucleic Acids Res., 47, 2019
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6TPQ
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![BU of 6tpq by Molmil](/molmil-images/mine/6tpq) | RNase M5 bound to 50S ribosome with precursor 5S rRNA | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | Deposit date: | 2019-12-13 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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5C0O
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![BU of 5c0o by Molmil](/molmil-images/mine/5c0o) | m1A58 tRNA methyltransferase mutant - Y78A | Descriptor: | S-ADENOSYLMETHIONINE, SULFATE ION, tRNA (adenine(58)-N(1))-methyltransferase TrmI | Authors: | Degut, C, Ponchon, L, Folly-Klan, M, Barraud, P, Tisne, C. | Deposit date: | 2015-06-12 | Release date: | 2015-07-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI. Biophys.Chem., 210, 2016
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5C1I
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![BU of 5c1i by Molmil](/molmil-images/mine/5c1i) | m1A58 tRNA methyltransferase mutant - D170A | Descriptor: | SULFATE ION, tRNA (adenine(58)-N(1))-methyltransferase TrmI | Authors: | Ponchon, L, Degut, C, Folly-Klan, M, Barraud, P, Tisne, C. | Deposit date: | 2015-06-14 | Release date: | 2015-06-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI. Biophys.Chem., 210, 2016
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7P9O
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![BU of 7p9o by Molmil](/molmil-images/mine/7p9o) | Structure of E.coli RlmJ in complex with a SAM analogue (CA) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl]amino}-5'-deoxyadenosine, Ribosomal RNA large subunit methyltransferase J | Authors: | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | Deposit date: | 2021-07-27 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7P8Q
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![BU of 7p8q by Molmil](/molmil-images/mine/7p8q) | Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GA-SAM), Ribosomal RNA large subunit methyltransferase J | Authors: | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | Deposit date: | 2021-07-23 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.289 Å) | Cite: | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7P9I
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![BU of 7p9i by Molmil](/molmil-images/mine/7p9i) | Structure of E.coli RlmJ in complex with an RNA conjugate (GAA-SAM) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GAA-SAM), Ribosomal RNA large subunit methyltransferase J | Authors: | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | Deposit date: | 2021-07-27 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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8CBK
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![BU of 8cbk by Molmil](/molmil-images/mine/8cbk) | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-His(5,Ser) | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, MAGNESIUM ION, Mitochondrial Precursor tRNA-His(5,Ser), ... | Authors: | MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. | Deposit date: | 2023-01-25 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
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8CBL
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![BU of 8cbl by Molmil](/molmil-images/mine/8cbl) | Structure of human mitochondrial RNase Z in complex with mitochondrial pre-tRNA-His(0,Ser) | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, Mitochondrial Precursor tRNA-His(0,Ser), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, YU, W, LUISI, B, TISNE, C. | Deposit date: | 2023-01-25 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
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8CBO
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![BU of 8cbo by Molmil](/molmil-images/mine/8cbo) | Structure of human mitochondrial MRPP1-MRPP2 in complex with mitochondrial pre-tRNA-Ile | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, Mitochondrial Precursor tRNA-Ile(5,4), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. | Deposit date: | 2023-01-25 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
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8CBM
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![BU of 8cbm by Molmil](/molmil-images/mine/8cbm) | Structure of human mitochondrial CCA-adding enzyme in complex with mitochondrial pre-tRNA-Ile | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, CCA tRNA nucleotidyltransferase 1, mitochondrial, ... | Authors: | MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. | Deposit date: | 2023-01-25 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
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