8CBO

Structure of human mitochondrial MRPP1-MRPP2 in complex with mitochondrial pre-tRNA-Ile

Summary for 8CBO

Entry DOI	10.2210/pdb8cbo/pdb
Related	8CBK 8CBL 8CBM
EMDB information	16547 16692
Descriptor	3-hydroxyacyl-CoA dehydrogenase type-2, tRNA methyltransferase 10 homolog C, Mitochondrial Precursor tRNA-Ile(5,4), ... (5 entities in total)
Functional Keywords	rna maturation, rna modification, mitochondrial trna, rna methyltransferase, mrpp1, mrpp2, mrpp3, rna binding protein, m6a, rna binding, rna recognition
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	158383.89
Authors	MEYNIER, V.,HARDWICK, S.,CATALA, M.,ROSKE, J.,OERUM, S.,CHIRGADZE, D.,BARRAUD, P.,LUISI, B.,TISNE, C. (deposition date: 2023-01-25, release date: 2024-06-12)
Primary citation	Meynier, V.,Hardwick, S.W.,Catala, M.,Roske, J.J.,Oerum, S.,Chirgadze, D.Y.,Barraud, P.,Yue, W.W.,Luisi, B.F.,Tisne, C. Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15:4683-4683, 2024 Cited by PubMed: 38824131 DOI: 10.1038/s41467-024-49132-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation