7ZLQ

Crystal structure of ADAR1-dsRBD3 dimer in complex with dsRNA

Summary for 7ZLQ

• Entry DOI: 10.2210/pdb7zlq/pdb
• Related: 7ZJ1
• Descriptor: Double-stranded RNA-specific adenosine deaminase, RNA (5'-R(*CP*GP*AP*AP*GP*CP*CP*UP*UP*CP*GP*CP*G)-3') (2 entities in total)
• Functional Keywords: editing, adar, rna-binding domain, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 30896.40

Authors

Mboukou, A.,Barraud, P. (deposition date: 2022-04-15, release date: 2023-10-25, Last modification date: 2024-11-27)

• Primary citation: Mboukou, A.,Rajendra, V.,Messmer, S.,Mandl, T.C.,Catala, M.,Tisne, C.,Jantsch, M.F.,Barraud, P.; Dimerization of ADAR1 modulates site-specificity of RNA editing; Nat Commun, 15:10051-, 2024; DOI: 10.1038/s41467-024-53777-2

Experimental method

X-RAY DIFFRACTION (2.8 Å)