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8YZ5
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BU of 8yz5 by Molmil
SARS-CoV-2 Delta Spike in complex with Fab of JE-5C
Descriptor: Fab heavy chain of JE-5C, Fab light chain of JE-5C, Spike glycoprotein
Authors:Chen, X, Wu, Y.-M.
Deposit date:2024-04-06
Release date:2024-06-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine.
Plos Pathog., 20, 2024
5DIK
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BU of 5dik by Molmil
Crystal structure of apo-lpg0406, a carboxymuconolactone decarboxylase family protein from Legionella pneumophila
Descriptor: Alkyl hydroperoxide reductase AhpD
Authors:Chen, X, Gong, X, Zhang, N, Ge, H.
Deposit date:2015-09-01
Release date:2015-10-14
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila
Protein Sci., 24, 2015
8YZ6
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BU of 8yz6 by Molmil
SARS-CoV-2 Spike (BA.1) in complex with Fab of JH-8B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain of JH-8B, ...
Authors:Chen, X, Wu, Y.-M.
Deposit date:2024-04-06
Release date:2024-06-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine.
Plos Pathog., 20, 2024
5DIP
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BU of 5dip by Molmil
Crystal structure of lpg0406 in reduced form from Legionella pneumophila
Descriptor: Alkyl hydroperoxide reductase AhpD, GLYCEROL, SODIUM ION
Authors:Chen, X, Gong, X, Zhang, N, Ge, H.
Deposit date:2015-09-01
Release date:2015-10-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structure of lpg0406, a carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response from Legionella pneumophila
Protein Sci., 24, 2015
6RWG
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BU of 6rwg by Molmil
Structure of HIV-1 CAcSP1NC mutant(W41A,M42A) interacting with maturation inhibitor EP39
Descriptor: Gag polyprotein, ZINC ION
Authors:Chen, X, Coric, P, Larue, V, Nonin-Lecomte, S, Bouaziz, S, Structural Genomics Consortium (SGC)
Deposit date:2019-06-05
Release date:2020-05-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag.
Eur.J.Med.Chem., 204, 2020
305D
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BU of 305d by Molmil
SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICATATIC) IN THE TETRAGONAL FORM
Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*AP*TP*AP*TP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1997-01-03
Release date:1997-09-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC).
J.Mol.Biol., 267, 1997
7AUD
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BU of 7aud by Molmil
Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ...
Authors:Chen, X, Oliver, A.W.
Deposit date:2020-11-02
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
306D
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BU of 306d by Molmil
SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICITACIC)
Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*TP*AP*CP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1997-01-03
Release date:1997-09-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC).
J.Mol.Biol., 267, 1997
7AUC
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BU of 7auc by Molmil
Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chen, X, Oliver, A.W.
Deposit date:2020-11-02
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021
304D
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BU of 304d by Molmil
SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICATATIC) IN THE MONOCLINIC FORM
Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*AP*TP*AP*TP*IP*C)-3')
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1997-01-03
Release date:1997-09-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC).
J.Mol.Biol., 267, 1997
6K9E
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BU of 6k9e by Molmil
The A form apo structure of NrS-1 C terminal region-CTR(305-718)
Descriptor: PHOSPHATE ION, Primase
Authors:Chen, X, Gan, J.
Deposit date:2019-06-14
Release date:2020-06-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase.
Nucleic Acids Res., 48, 2020
6LBG
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BU of 6lbg by Molmil
Structure of OR51B2 bound FEM1C
Descriptor: Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-14
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LE6
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BU of 6le6 by Molmil
Structure of LNLPTQGRAR bound FEM1C
Descriptor: Protein fem-1 homolog C,10-mer peptide, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-24
Release date:2020-10-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LBF
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BU of 6lbf by Molmil
Crystal structure of FEM1B
Descriptor: Protein fem-1 homolog B, SULFATE ION
Authors:Chen, X, Liao, S, Xu, C.
Deposit date:2019-11-14
Release date:2020-10-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.252 Å)
Cite:Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
1EGA
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BU of 1ega by Molmil
CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA
Descriptor: PROTEIN (GTP-BINDING PROTEIN ERA), SULFATE ION
Authors:Chen, X, Ji, X.
Deposit date:1998-12-01
Release date:1999-07-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif.
Proc.Natl.Acad.Sci.USA, 96, 1999
3B3Q
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BU of 3b3q by Molmil
Crystal structure of a synaptic adhesion complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Chen, X, Liu, H, Shim, A, Focia, P, He, X.
Deposit date:2007-10-22
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.
Nat.Struct.Mol.Biol., 15, 2008
7XWW
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BU of 7xww by Molmil
Crystal structure of NTR in complex with BN-XB
Descriptor: 2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-8-[1-[(4-nitrophenyl)methyl]pyridin-1-ium-4-yl]-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaene, Dihydropteridine reductase, FLAVIN MONONUCLEOTIDE
Authors:Chen, X, Chen, J, Li, J.L.
Deposit date:2022-05-27
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of NTR in complex with BN-XB
To Be Published
6Z2F
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BU of 6z2f by Molmil
Crystal structure of human AGX1 mutant complexed with UDPGLCNAC
Descriptor: UDP-N-acetylhexosamine pyrophosphorylase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Chen, X, van Aalten, D.M.F.
Deposit date:2020-05-15
Release date:2021-05-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human AGX1 mutant complexed with UDPGLCNAC
To Be Published
3VPN
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BU of 3vpn by Molmil
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
Descriptor: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2
Authors:Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J.
Deposit date:2012-03-05
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Essential role of E106 in the proton-coupled electron transfer in human
to be published
3VPM
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BU of 3vpm by Molmil
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
Descriptor: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2
Authors:Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J.
Deposit date:2012-03-05
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Essential role of E106 in the proton-coupled electron transfer in human ribonucleotide reductase M2 subunit
To be Published
3VPO
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BU of 3vpo by Molmil
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
Descriptor: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2
Authors:Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J.
Deposit date:2012-03-05
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Essential role of E106 in the proton-coupled electron transfer in human
to be published
159D
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BU of 159d by Molmil
SIDE BY SIDE BINDING OF TWO DISTAMYCIN A DRUGS IN THE MINOR GROOVE OF AN ALTERNATING B-DNA DUPLEX
Descriptor: DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*CP*IP*CP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Rao, S.T, Sundaralingam, M.
Deposit date:1994-02-10
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of two distamycin A molecules in the minor groove of an alternating B-DNA duplex.
Nat.Struct.Biol., 1, 1994
4XKB
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BU of 4xkb by Molmil
Crystal Structure of GENOMES UNCOUPLED 4 (GUN4) in Complex with Deuteroporphyrin IX
Descriptor: 3,3'-(3,7,12,17-tetramethylporphyrin-2,18-diyl)dipropanoic acid, Ycf53-like protein
Authors:Chen, X, Pu, H, Liu, L.
Deposit date:2015-01-11
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Crystal Structures of GUN4 in Complex with Porphyrins.
Mol Plant, 8, 2015
4XKC
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BU of 4xkc by Molmil
Crystal Structure of GENOMES UNCOUPLED 4 (GUN4) in Complex with Magnesium Deuteroporphyrin IX
Descriptor: Magnesium deuteroporphyrin IX, Ycf53-like protein
Authors:Chen, X, Pu, H, Liu, L.
Deposit date:2015-01-11
Release date:2015-05-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of GUN4 in Complex with Porphyrins.
Mol Plant, 8, 2015
217D
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BU of 217d by Molmil
CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Descriptor: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1995-07-18
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2, 1995

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