7C7S
 
 | | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | | Descriptor: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | Authors: | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | | Deposit date: | 2020-05-26 | | Release date: | 2020-07-01 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM structures of inactive and active GABABreceptor.
Cell Res., 30, 2020
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7Y3I
 | | Structure of DNA bound SALL4 | | Descriptor: | DNA (12-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-10 | | Release date: | 2022-10-26 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7EB2
 | | Cryo-EM structure of human GABA(B) receptor-Gi protein complex | | Descriptor: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | | Authors: | Shen, C, Mao, C, Xu, C, Jin, N, Zhang, H, Shen, D, Shen, Q, Wang, X, Hou, T, Rondard, P, Chen, Z, Pin, J, Zhang, Y, Liu, J. | | Deposit date: | 2021-03-08 | | Release date: | 2021-05-05 | | Last modified: | 2021-07-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of GABA B receptor-G i protein coupling.
Nature, 594, 2021
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6J8O
 | | Structure of a hypothetical protease | | Descriptor: | 8-mer peptide, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C. | | Deposit date: | 2019-01-20 | | Release date: | 2020-01-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.855 Å) | | Cite: | Structure of a hypothetical protease
To Be Published
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6J8F
 | | Crystal structure of SVBP-VASH1 with peptide mimic the C-terminal of alpha-tubulin | | Descriptor: | 8-mer peptide, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-01-18 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.283 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6J8N
 | | Crystal structure of SVBP-VASH1 complex, mutation C169A of VASH1 | | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-01-20 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6J9H
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6J91
 | | Structure of a hypothetical protease | | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C. | | Deposit date: | 2019-01-21 | | Release date: | 2019-06-19 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6K7V
 | | Structure of NLRP1 CARD filament | | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | | Authors: | Gong, Q, Xu, C, Zhang, J, Wu, B. | | Deposit date: | 2019-06-09 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6K9F
 | | Structure of unknow protein 4 | | Descriptor: | Caspase recruitment domain-containing protein 8 | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-15 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6K99
 | | Structure of ASC CARD filament | | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-14 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6K0X
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6K8J
 | | Structure of NLRC4 CARD filament | | Descriptor: | NLR family CARD domain-containing protein 4 | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-12 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6LBG
 | | Structure of OR51B2 bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-14 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LE6
 | | Structure of LNLPTQGRAR bound FEM1C | | Descriptor: | Protein fem-1 homolog C,10-mer peptide, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-24 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LBF
 | | Crystal structure of FEM1B | | Descriptor: | Protein fem-1 homolog B, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-14 | | Release date: | 2020-10-21 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.252 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LDP
 | | Structure of CDK5R1-bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-22 | | Release date: | 2020-10-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LEN
 | | Structure of NS11 bound FEM1C | | Descriptor: | Protein fem-1 homolog C,NS11 peptide | | Authors: | Chen, x, Liao, S, Xu, C. | | Deposit date: | 2019-11-25 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.383 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LF0
 | | Structure of FEM1C | | Descriptor: | Protein fem-1 homolog C, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-27 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LBN
 | | Structure of SIL1-bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-14 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.899 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LEY
 | | Structure of Sil1G bound FEM1C | | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2019-11-27 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6MCQ
 | | L. pneumophila effector kinase LegK7 in complex with human MOB1A | | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2018-09-01 | | Release date: | 2019-09-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6MCP
 | | L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A | | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | Deposit date: | 2018-09-01 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7Y3M
 | | Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA | | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.723 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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7Y3K
 | | Structure of SALL4 ZFC4 bound with 16 bp AT-rich dsDNA | | Descriptor: | DNA (16-mer), Sal-like protein 4, ZINC ION | | Authors: | Ru, W, Xu, C. | | Deposit date: | 2022-06-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
J.Biol.Chem., 298, 2022
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